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Protein
Submitted name:

Mastermind-like transcriptional coactivator 2

Gene

Maml2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-MMU-2122947 NOTCH1 Intracellular Domain Regulates Transcription
R-MMU-2197563 NOTCH2 intracellular domain regulates transcription
R-MMU-350054 Notch-HLH transcription pathway
R-MMU-8941856 RUNX3 regulates NOTCH signaling

Names & Taxonomyi

Protein namesi
Submitted name:
Mastermind-like transcriptional coactivator 2Imported
Gene namesi
Name:Maml2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 9

Organism-specific databases

MGIiMGI:2389460 Maml2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000031925 Expressed in 22 organ(s), highest expression level in fibroblast

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410JA0Q Eukaryota
ENOG4111GMG LUCA
GeneTreeiENSGT00530000063317
OMAiFSNRYGD

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

E9Q7L5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNSQQSLLNQ QMMGKKQTLQ RPTMEQKQQL LLQQQMLADA EKLSPQDQMN
60 70 80 90 100
RHLTRPPPDY KDQRRNTGTL QPAAQYSGGS STVSLNSNQA LTNPVSTHTI
110 120 130 140 150
LTPNSSLMST SHGMRMPLLS TVQNIGMYGN LPCNQPGTYN VTSTMNQLTQ
160 170 180 190 200
QRNTTQLITN QNNPLMSRPS PLGANNGNNV ATFGAGSAGS SQQLRPNLAH
210 220 230 240 250
SLSGMSAQRS STVMITANTT ATNWASQEVT GKQQEALKST GVRFPTSTPA
260 270 280 290 300
AYTPNQSLQP GVGSQPFSQR AVAPPSQLSP AVQMRPMNQM NQALNGQTLG
310 320 330 340 350
SLRGLNLRPN QLAAQSLSNM NPSGTGLNHP RTGTNQPPSL TPNAFPSSNQ
360 370 380 390 400
SSRAFQGPDH GSDLAFDFLS QQSDSMCPAL NSDADFIDSL LKTEPGNDDW
410
MKDINLDEIL GSNS
Length:414
Mass (Da):44,565
Last modified:April 5, 2011 - v1
Checksum:i901A5A0B12168B4A
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F6U238F6U238_MOUSE
Mastermind-like transcriptional coa...
Maml2
1,170Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC155923 Genomic DNA No translation available.
AC169127 Genomic DNA No translation available.
AC241616 Genomic DNA No translation available.
CAAA01067074 Genomic DNA No translation available.
CAAA01078075 Genomic DNA No translation available.
CAAA01176476 Genomic DNA No translation available.
CAAA01194877 Genomic DNA No translation available.
RefSeqiNP_776137.2, NM_173776.3
UniGeneiMm.116898
Mm.359472
Mm.393962

Genome annotation databases

EnsembliENSMUST00000034401; ENSMUSP00000034401; ENSMUSG00000031925
ENSMUST00000177755; ENSMUSP00000136866; ENSMUSG00000031925
GeneIDi270118
UCSCiuc012gob.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC155923 Genomic DNA No translation available.
AC169127 Genomic DNA No translation available.
AC241616 Genomic DNA No translation available.
CAAA01067074 Genomic DNA No translation available.
CAAA01078075 Genomic DNA No translation available.
CAAA01176476 Genomic DNA No translation available.
CAAA01194877 Genomic DNA No translation available.
RefSeqiNP_776137.2, NM_173776.3
UniGeneiMm.116898
Mm.359472
Mm.393962

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000034401; ENSMUSP00000034401; ENSMUSG00000031925
ENSMUST00000177755; ENSMUSP00000136866; ENSMUSG00000031925
GeneIDi270118
UCSCiuc012gob.1 mouse

Organism-specific databases

CTDi84441
MGIiMGI:2389460 Maml2

Phylogenomic databases

eggNOGiENOG410JA0Q Eukaryota
ENOG4111GMG LUCA
GeneTreeiENSGT00530000063317
OMAiFSNRYGD

Enzyme and pathway databases

ReactomeiR-MMU-2122947 NOTCH1 Intracellular Domain Regulates Transcription
R-MMU-2197563 NOTCH2 intracellular domain regulates transcription
R-MMU-350054 Notch-HLH transcription pathway
R-MMU-8941856 RUNX3 regulates NOTCH signaling

Miscellaneous databases

ChiTaRSiMaml2 mouse
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000031925 Expressed in 22 organ(s), highest expression level in fibroblast

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiE9Q7L5_MOUSE
AccessioniPrimary (citable) accession number: E9Q7L5
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: November 7, 2018
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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