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Protein
Submitted name:

Serine/arginine-rich-splicing factor 11

Gene

Srsf11

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRNA-bindingPROSITE-ProRule annotation

Enzyme and pathway databases

ReactomeiR-MMU-109688 Cleavage of Growing Transcript in the Termination Region
R-MMU-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript
R-MMU-72163 mRNA Splicing - Major Pathway
R-MMU-72187 mRNA 3'-end processing

Names & Taxonomyi

Protein namesi
Submitted name:
Serine/arginine-rich-splicing factor 11Imported
Gene namesi
Name:Srsf11Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 3

Organism-specific databases

MGIiMGI:1916457 Srsf11

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

MaxQBiE9Q6E5
PaxDbiE9Q6E5
PeptideAtlasiE9Q6E5
PRIDEiE9Q6E5

PTM databases

iPTMnetiE9Q6E5

Expressioni

Gene expression databases

BgeeiENSMUSG00000055436 Expressed in 302 organ(s), highest expression level in membranous labyrinth
ExpressionAtlasiE9Q6E5 baseline and differential
GenevisibleiE9Q6E5 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000113685

Structurei

3D structure databases

ProteinModelPortaliE9Q6E5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini61 – 141RRMInterPro annotationAdd BLAST81

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili446 – 466Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG4676 Eukaryota
ENOG410YYIR LUCA
GeneTreeiENSGT00730000110872
InParanoidiE9Q6E5
KOiK12899
OrthoDBiEOG091G0QKH
TreeFamiTF106266

Family and domain databases

Gene3Di3.30.70.330, 1 hit
InterProiView protein in InterPro
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
IPR034447 SRSF11
PANTHERiPTHR32343:SF6 PTHR32343:SF6, 1 hit
PfamiView protein in Pfam
PF00076 RRM_1, 1 hit
SMARTiView protein in SMART
SM00360 RRM, 1 hit
SUPFAMiSSF54928 SSF54928, 1 hit
PROSITEiView protein in PROSITE
PS50102 RRM, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All

E9Q6E5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSPPAPGTA GPTSPSVALT NLALRRNFFR EAARAMSSTA VVPSAPGPGP
60 70 80 90 100
GPSGGPGGGT EVIQVTNVSP SASSEQMRTL FGFLGKIDEL RLFPPDDSPL
110 120 130 140 150
PVSSRVCFVK FHDPDSAVVA QHLTNTVFVD RALIVVPYAE GVIPDETKAL
160 170 180 190 200
SLLAPANAVA GLLPGGGLLP TPNPLTQIGA VPLAALGAPA LDPALAALGL
210 220 230 240 250
PGTNLNSQSL AADQLLKLMS TVDPKLNHVA AGLVSPSLKS DTSSKEIEEA
260 270 280 290 300
MKRVREAQSL ISAAIEPDKK EEKRRHSRSR SRSRRRRTPS SSRHRRSRSR
310 320 330 340 350
SRRRSHSKSR SRRRSKSPRR RRSHSRERGR RSRSTSKARD KKKEDKEKKR
360 370 380 390 400
SKTPPKSYST ARRSRSASRE RRRRRSRSGT RSPKKPRSPK RKLSRSPSPR
410 420 430 440 450
RHKKEKKKDK DKERSRDERE RSTSKKKRSK DKEKERERKS ESDKDVKQVT
460 470 480 490 500
RDYDEEEQGY DSEKEKKEEK RPTEAVSPKT KECSVEKGVG DLRESKVNGD
510
DHHEEDMDMS D
Length:511
Mass (Da):56,698
Last modified:April 5, 2011 - v1
Checksum:i1DE78B7539867B1E
GO

Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q3UIX4Q3UIX4_MOUSE
Serine/arginine-rich-splicing facto...
Srsf11 Sfrs11, mCG_11658
476Annotation score:
F6RDI8F6RDI8_MOUSE
Serine/arginine-rich-splicing facto...
Srsf11
500Annotation score:
D6RE22D6RE22_MOUSE
Serine/arginine-rich-splicing facto...
Srsf11
112Annotation score:
D3Z4B0D3Z4B0_MOUSE
Serine/arginine-rich-splicing facto...
Srsf11
192Annotation score:
F6TN80F6TN80_MOUSE
Serine/arginine-rich-splicing facto...
Srsf11
101Annotation score:
F6X2U6F6X2U6_MOUSE
Serine/arginine-rich-splicing facto...
Srsf11
53Annotation score:
A0A0G2JEG1A0A0G2JEG1_MOUSE
Serine/arginine-rich-splicing facto...
Srsf11
175Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC145301 Genomic DNA No translation available.
RefSeqiNP_001087221.1, NM_001093752.1
UniGeneiMm.223946

Genome annotation databases

EnsembliENSMUST00000121326; ENSMUSP00000113685; ENSMUSG00000055436
GeneIDi69207
KEGGimmu:69207
UCSCiuc008rvo.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC145301 Genomic DNA No translation available.
RefSeqiNP_001087221.1, NM_001093752.1
UniGeneiMm.223946

3D structure databases

ProteinModelPortaliE9Q6E5
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000113685

PTM databases

iPTMnetiE9Q6E5

Proteomic databases

MaxQBiE9Q6E5
PaxDbiE9Q6E5
PeptideAtlasiE9Q6E5
PRIDEiE9Q6E5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000121326; ENSMUSP00000113685; ENSMUSG00000055436
GeneIDi69207
KEGGimmu:69207
UCSCiuc008rvo.1 mouse

Organism-specific databases

CTDi9295
MGIiMGI:1916457 Srsf11

Phylogenomic databases

eggNOGiKOG4676 Eukaryota
ENOG410YYIR LUCA
GeneTreeiENSGT00730000110872
InParanoidiE9Q6E5
KOiK12899
OrthoDBiEOG091G0QKH
TreeFamiTF106266

Enzyme and pathway databases

ReactomeiR-MMU-109688 Cleavage of Growing Transcript in the Termination Region
R-MMU-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript
R-MMU-72163 mRNA Splicing - Major Pathway
R-MMU-72187 mRNA 3'-end processing

Miscellaneous databases

ChiTaRSiSrsf11 mouse
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000055436 Expressed in 302 organ(s), highest expression level in membranous labyrinth
ExpressionAtlasiE9Q6E5 baseline and differential
GenevisibleiE9Q6E5 MM

Family and domain databases

Gene3Di3.30.70.330, 1 hit
InterProiView protein in InterPro
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
IPR034447 SRSF11
PANTHERiPTHR32343:SF6 PTHR32343:SF6, 1 hit
PfamiView protein in Pfam
PF00076 RRM_1, 1 hit
SMARTiView protein in SMART
SM00360 RRM, 1 hit
SUPFAMiSSF54928 SSF54928, 1 hit
PROSITEiView protein in PROSITE
PS50102 RRM, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE9Q6E5_MOUSE
AccessioniPrimary (citable) accession number: E9Q6E5
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: November 7, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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