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Protein
Submitted name:

Zinc finger protein 277

Gene

Zfp277

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • RNA polymerase II proximal promoter sequence-specific DNA binding Source: MGI

GO - Biological processi

  • cellular response to hydrogen peroxide Source: MGI
  • regulation of cellular senescence Source: MGI

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Zinc finger protein 277Imported
Gene namesi
Name:Zfp277Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 12

Organism-specific databases

MGIiMGI:1890393 Zfp277

PTM / Processingi

Proteomic databases

MaxQBiE9Q6D6
PaxDbiE9Q6D6
PeptideAtlasiE9Q6D6
PRIDEiE9Q6D6

Expressioni

Gene expression databases

BgeeiENSMUSG00000055917 Expressed in 36 organ(s), highest expression level in female gonad
ExpressionAtlasiE9Q6D6 baseline and differential
GenevisibleiE9Q6D6 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000064226

Structurei

3D structure databases

ProteinModelPortaliE9Q6D6
SMRiE9Q6D6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini351 – 380C2H2-typeInterPro annotationAdd BLAST30
Domaini482 – 513C2H2-typeInterPro annotationAdd BLAST32

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili272 – 292Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG2482 Eukaryota
ENOG410XQ2B LUCA
GeneTreeiENSGT00390000010852
InParanoidiE9Q6D6
OrthoDBiEOG091G0A09
TreeFamiTF318036

Family and domain databases

InterProiView protein in InterPro
IPR040048 ZNF277
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PANTHERiPTHR13267 PTHR13267, 1 hit
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 5 hits
SUPFAMiSSF57667 SSF57667, 2 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 2 hits
PS50157 ZINC_FINGER_C2H2_2, 2 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

E9Q6D6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAASEVQGLP VDPREAGVRG VRGGIGHTDH EGHLGSFQLL ATINKAAMNI
60 70 80 90 100
VEHVSFLPVG TSSGYIAASS GITMSNFLRN RQTDFQSGCT SLQSHQQWRS
110 120 130 140 150
VPLSPHPHQH LLSPEFLILA ILTGVRWNLR IALICISLMI KDAEHFFRCF
160 170 180 190 200
SAIWYSSDSK DCILEPLSLP ESPGGTTALE GSPSVPCIFC EEHFPMAEQD
210 220 230 240 250
KLLKHMIIEH KIVIADVKLV ADFRRYILYW RKRFTEQPIT DFCSVIRINS
260 270 280 290 300
TAPFEEQDNY YLLCDALPED RILREELQKH KLKEVLDQQQ RERNDTSFHG
310 320 330 340 350
VCMFCSEEFR GNRSVLLNHM AREHAFNIGL PDNIVNCAEF LCTLQKKLDN
360 370 380 390 400
LQCLYCEKTF RDKNTLKDHM RKKQHRRINP KNREYDRFYV INYLELGKSW
410 420 430 440 450
EEVQSEDDRE LLDLQEDDWS DWQEYPVSAV CLFCEKQEET IDKLYVHMKD
460 470 480 490 500
THEFDLLRIK SELGLNFYQQ VKLVNFIRRQ VHQCKCYSCH VKFKSKADLR
510 520 530 540 550
THMEDTKHTS LLPDRKTWDQ LEYYFPTYEN DTLLCTLSDS ESDLTAQEQT
560 570 580
ENVPVISEDT SRLCALKQSS VLNQLLLQGC LEN
Length:583
Mass (Da):67,644
Last modified:April 5, 2011 - v1
Checksum:i6F90ABF919E4C6AA
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q3U0V6Q3U0V6_MOUSE
Zinc finger protein 277
Zfp277
457Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC123855 Genomic DNA No translation available.
AC158517 Genomic DNA No translation available.
RefSeqiNP_766163.2, NM_172575.3
UniGeneiMm.26852

Genome annotation databases

EnsembliENSMUST00000069692; ENSMUSP00000064226; ENSMUSG00000055917
GeneIDi246196
KEGGimmu:246196
UCSCiuc007nla.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC123855 Genomic DNA No translation available.
AC158517 Genomic DNA No translation available.
RefSeqiNP_766163.2, NM_172575.3
UniGeneiMm.26852

3D structure databases

ProteinModelPortaliE9Q6D6
SMRiE9Q6D6
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000064226

Proteomic databases

MaxQBiE9Q6D6
PaxDbiE9Q6D6
PeptideAtlasiE9Q6D6
PRIDEiE9Q6D6

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000069692; ENSMUSP00000064226; ENSMUSG00000055917
GeneIDi246196
KEGGimmu:246196
UCSCiuc007nla.2 mouse

Organism-specific databases

CTDi246196
MGIiMGI:1890393 Zfp277

Phylogenomic databases

eggNOGiKOG2482 Eukaryota
ENOG410XQ2B LUCA
GeneTreeiENSGT00390000010852
InParanoidiE9Q6D6
OrthoDBiEOG091G0A09
TreeFamiTF318036

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000055917 Expressed in 36 organ(s), highest expression level in female gonad
ExpressionAtlasiE9Q6D6 baseline and differential
GenevisibleiE9Q6D6 MM

Family and domain databases

InterProiView protein in InterPro
IPR040048 ZNF277
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PANTHERiPTHR13267 PTHR13267, 1 hit
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 5 hits
SUPFAMiSSF57667 SSF57667, 2 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 2 hits
PS50157 ZINC_FINGER_C2H2_2, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiE9Q6D6_MOUSE
AccessioniPrimary (citable) accession number: E9Q6D6
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: November 7, 2018
This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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