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Protein
Submitted name:

AHNAK nucleoprotein (desmoyokin)

Gene

Ahnak

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • S100 protein binding Source: MGI
  • structural molecule activity conferring elasticity Source: UniProtKB

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
AHNAK nucleoprotein (desmoyokin)Imported
Gene namesi
Name:AhnakImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 19

Organism-specific databases

MGIiMGI:1316648 Ahnak

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

MaxQBiE9Q616
PaxDbiE9Q616
PeptideAtlasiE9Q616
PRIDEiE9Q616

PTM databases

iPTMnetiE9Q616
PhosphoSitePlusiE9Q616

Expressioni

Gene expression databases

BgeeiENSMUSG00000069833 Expressed in 284 organ(s), highest expression level in urinary bladder
ExpressionAtlasiE9Q616 baseline and differential
GenevisibleiE9Q616 MM

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

ComplexPortaliCPX-905 AHNAK - Annexin A2 - S100-A10 complex
IntActiE9Q616, 1 interactor
STRINGi10090.ENSMUSP00000090633

Structurei

3D structure databases

ProteinModelPortaliE9Q616
SMRiE9Q616
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 57PDZInterPro annotationAdd BLAST57

Phylogenomic databases

eggNOGiENOG410IGIF Eukaryota
ENOG410XQS3 LUCA
GeneTreeiENSGT00530000063716
InParanoidiE9Q616
OMAiINAPHGK
OrthoDBiEOG091G01FG
TreeFamiTF350595

Family and domain databases

InterProiView protein in InterPro
IPR001478 PDZ
IPR036034 PDZ_sf
SMARTiView protein in SMART
SM00228 PDZ, 1 hit
SUPFAMiSSF50156 SSF50156, 1 hit
PROSITEiView protein in PROSITE
PS50106 PDZ, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

E9Q616-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEKEEETTRE LLLPNWQGSG SHGLTIAQRD DGVFVQEVMQ NSPAARTGVV
60 70 80 90 100
KEGDQIVGAT IYFDNLQSGE VTQLLNTMGH HTVGLKLHRK GDRSPEPGQT
110 120 130 140 150
WTHEVFSSRS SEVVLSGDDE DYQRIYTTKI KPRLRSEDGV EGDLGETQSR
160 170 180 190 200
TITVTRRVTA YTVDVTGREG VKDIDITSPE FMIKIPRHEV TEISNTDVET
210 220 230 240 250
QPGKTVIRLP SGSGPASPTT GSAVDIRAGA ISASGPELEG AGHSKFQVTV
260 270 280 290 300
PGAKVGSLDV NVKAKGLDLG GKGGIRVPGV DVSSSLGAGS VEVQAPSLQS
310 320 330 340 350
GDIGKIKIPT MKVPKFGVSA GLDGQIPEVG LSVSAPESSV GHKGDKPGLA
360 370 380 390 400
IGGNIQAPHL EVNPSSVNIE GLEGKLKGPQ ITGPSLEGDL GLKGTKLQGN
410 420 430 440 450
IGMDACASKI EGSITGPSVE IGTPDVDVHG LGGKLNMPKM KVPKFSASGS
460 470 480 490 500
KGEGIGLDVA LPTGEVTLPG VSGDVSLPEI ATGGLEGKMK GAKVKTPEMI
510 520 530 540 550
IQKPKISMQD VDLSLGSCKL KGNMKTSAPE VKGDVKGPQM AVKGSRVDIE
560 570 580 590 600
TPNLEGTLTG PKISSPSGKI GACRISMADV DLNVAAPKGK GGVDVILPNV
610 620 630 640 650
EGKAKGLEVD VKGPKMDISA PDVEVHGPEW NLKMPKFSVP GVKGEGLDVN
660 670 680 690 700
VTLPEGDISI SGPKVNVEAP NVNMEGLGGK LKGPDINLPE VSVKTPKISM
710 720 730 740 750
PDVDLHIKGP KVKGEYEVTP PKLEGELKGS KVDIDTPQVD VHGPDLKIPK
760 770 780 790 800
MKMPKFSVPG FKAEGPEVDV NLPKADLDIS GTKVEVSAPD VSIEGSEGKL
810 820 830 840 850
KGHKFKMPEM NIRAPKISMP DVDLHLKGPN VKGEYDVTVP RAEGEIKVPD
860 870 880 890 900
VELKSAKLDI DVPNVDVQGP ELHMKMPKIK MPKFGMPGFK AESPEMEVNL
910 920 930 940 950
PKSDIDVSGP NVDVKVPDVN IEGPEGKLKG PKLKMPEMNI KAPKISMPDV
960 970 980 990 1000
DLHMKGPKVK GEYDVTMPKL EGDLKGPKVD VSVPDVDVHG PDWNLKMPKI
1010 1020 1030 1040 1050
KMPKFSMPSL KGEGPELDVN MPKADVDISV PKLDISAPDL NLEGPEGKLK
1060 1070 1080 1090 1100
GPKFKMPEMH FKAPKVSLPD VDLDLKGPKM KGNLDMSAPK IEGEMKAPDV
1110 1120 1130 1140 1150
DIKGPNVDIK APEVDVQGPE WSLKMPKMKM PKFSMPTLKG EGPDVDVSLP
1160 1170 1180 1190 1200
KATIDVSGPK LDIETSDVSL EGPEGKLKGP KFKMPDMHFK APKISMPDVD
1210 1220 1230 1240 1250
LNMKGPKVKG DMDVTVPKIE GEMKVPDVDI KGPKVDISAP DVDVQGPDWH
1260 1270 1280 1290 1300
LKMPKMKMPK FSMPGFKAEG PEVSLPKADL DVSGPKVDID VPDVNIEGPD
1310 1320 1330 1340 1350
AKLKGPKFKM PEMNIKAPKI SMPDLHLKGP KVKGDVDVSL PKVEGDLKGP
1360 1370 1380 1390 1400
DIDIKGPKMD INAPDMDVQG PDWHLKMPKM KMPKFSMPGF KAEGPEVDVN
1410 1420 1430 1440 1450
LPKADIDVSG PKVDIEAPDV SIEGPEGKLK GPKFKMPDMH FKAPKISMPD
1460 1470 1480 1490 1500
VDLNIKGPKG KADVDASLPE VEGGVKVPDV DIKGPKVGID APDVEVHGPD
1510 1520 1530 1540 1550
WHLKMPKVKM PKFSMPGFKG EGPEVDIPKA NIDVSGPKVD IDVPDVNIEG
1560 1570 1580 1590 1600
PDTKLKGPKF KMPEMNIKPQ KISMPDVSLN LKGPKVKADC DVSVPKVGGE
1610 1620 1630 1640 1650
IKAPAVDIKG PKVEAPDVEV HGPDWHLKMP KVKMPKFSMP GFKGEGAEVD
1660 1670 1680 1690 1700
VNLQKANIDV SGPKVDIDVP DVNIEGPEGK LKGPKFKMPS MNIQTHKISM
1710 1720 1730 1740 1750
PDVGLNLKGP KLKSGVDVSL PKVEGELKGP EVDVDVGDID IECPEGKLKG
1760 1770 1780 1790 1800
PKFKMPDMHF KTPKISMPDV DLHLKGPKVK GDMDVTMPKI EGEMKVPDVD
1810 1820 1830 1840 1850
IKGPKVDINA PDVDVRGPDW HLKMPKVKMP KFSMPGFKAE GPEVDVNLPK
1860 1870 1880 1890 1900
ADIDVSGPKV DIDVPDLDIE GPEGKLKGSK FKMPKLNIKA AKISMPDVDL
1910 1920 1930 1940 1950
NFKGPKLKGE IDASVPEMEA DLRGPQVDIK GTNVDVKVPD VDLECPDAKL
1960 1970 1980 1990 2000
KGPKFKMPDM HFKAPKISMP DVDLHLKGPK VKGDMDVTVP KLEGELKGPS
2010 2020 2030 2040 2050
VDVEVPDVDL ECPDAKLKGP KFKMPDMHFK APKISMPDVD LHLKGPKVKG
2060 2070 2080 2090 2100
DMDVTVPKLE GELKGPSVDV EVPDVDLECP DAKLKGPKFK MPDMHFKAPK
2110 2120 2130 2140 2150
ISMPDVDLHL KGPKVKGDVD VTVPKLEGEL KGPSVDVEVP DVDLECPDAK
2160 2170 2180 2190 2200
LKGPKFKMPD MHFKAPKISM PDVDLHLKGP KVKGDMDVTV PKIEGEMKVP
2210 2220 2230 2240 2250
DVDIKGPKVD INAPDVDVRG PDWHLKMPKM KMPKFSMPGF KAEGPEVDVN
2260 2270 2280 2290 2300
LPKADIDVSG PKVDIDVPDV NIEGPEGKLK GPKFKMPDMH FKAPKISMPD
2310 2320 2330 2340 2350
VDFNLKGPKI KGDIDVSVPK IEGELKGPEL DLKGPKLDAN IPEVAVEGPE
2360 2370 2380 2390 2400
GKWKSPKFKM PDMHFKTPKI SMPDIDLHLK SPKIKGEVDV DVPKLEGDLK
2410 2420 2430 2440 2450
GPNVDMSRPD IEIEGPEGKL KGPKFKMPEM NIKAPKISMP DFDLHLKGPK
2460 2470 2480 2490 2500
VKGDVDISLP KVEGDIKGPE VDIKGPKVDI NAPDVDVQGP DWHLKMPKMK
2510 2520 2530 2540 2550
MPKFSMPGFK AEGPEVDVNL PKADIDVSGP KVDIDVPDVN IEGPDAKLKG
2560 2570 2580 2590 2600
PKFKMPEMNI KAPKISMPDI DLNLKGPKVK GDVDVSLPKV EGEIKVPEVD
2610 2620 2630 2640 2650
IKGPKVDIDV PDVDVHGPDW HLKMPKIKMP KFSMPGFKGE GPEVDVSLPN
2660 2670 2680 2690 2700
ADLDVSGPKV DIDVPDVNIE GPDAKLKGPK FKMPEMNIKA PKISMPDLHL
2710 2720 2730 2740 2750
KGPKVKGDVD VSLPKVEGDL KGPDVDIKGP KMDINAPDMD VQGPDWHLKM
2760 2770 2780 2790 2800
PKMKMPKFSM PGFKAEGPEV DVNLPKADLD VSGPKVDIDV PDVNIEGPDA
2810 2820 2830 2840 2850
KLKGPKFKMP EMNIKAPKIS MPDIDLNLKG PKVKGDVDMS LPKVEGEIKV
2860 2870 2880 2890 2900
PEVDIKGPKV DIDVPDVDVH GPDWHLKMPK VKMPKFSMPG FKGEGPEVDV
2910 2920 2930 2940 2950
NLPKADLDVS GPKVDIDVPD VNIEGPDAKL KGPKFKMPEV NIKAPKISMP
2960 2970 2980 2990 3000
DLNLNLKGPN VKGDVDVSIP NIEGDLKGPS LDIKSPKLDV NAPDIDVHGP
3010 3020 3030 3040 3050
EGKLKGPKLK MPDMHVSMPK ISMPEIDLNL KGSKVKGDVD ISGPKLEGDI
3060 3070 3080 3090 3100
KVPRVDLKGP EVDISAPKVN IDGKAKKSRF KLPKFNFSGS KVQTPEVDVK
3110 3120 3130 3140 3150
LKKPDVDITA PKVDINAPEV EVQGKVKGSK FKMPFLSISS PKVSMPDVEL
3160 3170 3180 3190 3200
NLKGPKVKGD LDAAGPNLEG DFKGPKVDIK APDVQLNAPD VDVHGPEWNL
3210 3220 3230 3240 3250
KMPKMKMPKF GVSGIKAEGP DVAVDLPKGD INIEGPSMNI EGPELNVECP
3260 3270 3280 3290 3300
EGSLKGPKFK MPEMNIKAPK ISMPDIDLNL KGPKVKGDVD VSLPKVEGEI
3310 3320 3330 3340 3350
KVPEVDIKGP KVDIDVPDVD VHGPDWHLKM PKVKMPKFSM PGFKGEGPEV
3360 3370 3380 3390 3400
DVSLPKANID VSGPKVDIDV PDVNIEGPDA KLKGPKFKMP EMNIKAPKIS
3410 3420 3430 3440 3450
MPDIDLNLKG PKVKGDVDVS LPKVEGEIKV PEVDIKGPKV DIDVPDVDVH
3460 3470 3480 3490 3500
GPDWHLKMPK IKMPKFSMPG FKGEGPEVDV SLPKADLDVS GPKVDIDVPD
3510 3520 3530 3540 3550
VNIEGPDAKL KGPKFKMPEM NIKAPKISMP DIDLNLKGPK VKGDVDVSLP
3560 3570 3580 3590 3600
KVEGEIKVPE VDIKDPKVDI DVPDVDVHGP DWHLKMPKIK MPKFSMPGFK
3610 3620 3630 3640 3650
GEGPEVDVNL PKADLDVSGP KVDIDVPDVN IEGPDAKLKG PKFKMPEMNI
3660 3670 3680 3690 3700
KAPKISMPDL HLKGPKVKGD VDVSLPKVEG DLKGPDVDIK GPKMDINAPD
3710 3720 3730 3740 3750
MDVQGPDWHL KMPKMKMPKF SMPGFKAEGP EVDVNLPKVD LDVSGPKVDI
3760 3770 3780 3790 3800
DVPDVNIEGP DAKLKGPKFK MPEMNIKAPK ISMPDIDLNL KGPKVKGDVD
3810 3820 3830 3840 3850
MSLPKVEGEI KVPEVDIKGP KVDIDVPDVD VHGPDWHLKM PKVKMPKFSM
3860 3870 3880 3890 3900
PGFKGEGPEV DVNLPKADLD VSGPKVDIDV PDVNIEGPDA KLKGPKFKMP
3910 3920 3930 3940 3950
EMNIKAPKIS MPDLHLKGPK VKGDVDVSLP KVEGDLKGPE VDIKGPKMDI
3960 3970 3980 3990 4000
SAPDVDVHGP DWHLKMPKVK MPKFSMPGFK GEGPEVDVNL PKADLDVSGP
4010 4020 4030 4040 4050
KVDIEGPNVN IEGPEGKLKG PKFKMPDLHL KAPKISMPEI DLNLKGPKLK
4060 4070 4080 4090 4100
GDVDVSLPKV EGDLKGPEVD IKGPKVDISA PDMDVHGPDW HLKMPKMKMP
4110 4120 4130 4140 4150
KFSMPGFKAE GPEVDVNLPK ADIDVSGPKV DIDVPDVNIE GPDAKLKGPK
4160 4170 4180 4190 4200
FKMPEMNIKA PKISMPDFDL HLKGPKVKGD VDASLPKMEG ELKGPGIDIK
4210 4220 4230 4240 4250
CPTVDIDTPD VNIEVPEGKL KGPKFKMPDM HIKAPKISMP DFDLNLKGPK
4260 4270 4280 4290 4300
VKGDVDLALP NVEGDLKGPE IDIEGPEGKL KGPKFKVPDV QFKTPQISMS
4310 4320 4330 4340 4350
DIDLNVKGPK IKGDLDISIP KPEGDLKGPK VDIKGPKLDI DTPDIDIHGP
4360 4370 4380 4390 4400
EGKLKGPKFK MPDLHLKAPK ISMPEVDLNL KGPKVKGDVD VSLPKVEGDL
4410 4420 4430 4440 4450
KGPEVDIKGP KVDISAPDVD VHGPDWHLKM PKVKMPKFSM PGFKGEGPEV
4460 4470 4480 4490 4500
DVSLPKANID VSGPKVDIDV PDVNIEGPDA KLKGPKFKMP EMNIKAPKIS
4510 4520 4530 4540 4550
MPDIDLNLKG PKVKGDVDVS LPKVEGEIKV PEVDIKGPKV DIDVPDVDVH
4560 4570 4580 4590 4600
GPDWHLKMPK VKMPKFSMPG FKGEGPEVDV NLPKADLDVS GPKVDIDVPD
4610 4620 4630 4640 4650
VNVEGPDMKV KGPKFRMPEI NIKAPKISMP DVDLELKGPK VKGAFDGSVP
4660 4670 4680 4690 4700
KIEGTLKGPE IDMKGPGLDF EGPDAKLSGP NLKMPSLEVS VPKITGPDAN
4710 4720 4730 4740 4750
VHLKTPKVGI SAPKLGGGEV DLKGPKVDLE TPSLDVHMES PDINIEGPDV
4760 4770 4780 4790 4800
KVPKFKKPKF GFGAKSPKAD IKTPTVDVTV PEAELNVDSP EINIGGKSKK
4810 4820 4830 4840 4850
SKFKMPKIHM SGPKVKAKKQ GFDLNIPGGE IDTSLKAPDV DVSVAGPDAA
4860 4870 4880 4890 4900
LKAEVKSPKV KKTMFGKMYF PDVEFDIKSP KFKAEAPLPS PKLEGEIKVP
4910 4920 4930 4940 4950
DVDISSPGIN VEAPDIHMKA PKFKVPGVEA SGPKIEGNLK GPKVQANLDT
4960 4970 4980 4990 5000
PDINIEGPEA KIKAPSFSVS APQVSIPDVN VNLKGPKIKG DVPSVGLEGP
5010 5020 5030 5040 5050
NIDLQGPEGK IKFPKFSLPK ISAPGVKMEG GSTEIGAQMP SLEGGLSTSD
5060 5070 5080 5090 5100
MKLEGPHLSL KGPGVDLPSV DLSMPKVSGP DLDMNLKGPS LKGDLGASSP
5110 5120 5130 5140 5150
SMKLHAPGLD LKGVGGKVHI GADGVKMSGI DATTALSVGA PDVTLKGPSL
5160 5170 5180 5190 5200
QGDLAVSGDI KCPKVSVATP DVSLEASEGA VKLPHMKLPQ FGISTPGSDL
5210 5220 5230 5240 5250
DINIKGPQVC GELKGSGMDV NLKGPQISAP SMDFNLEGPK VKGSLGAAGE
5260 5270 5280 5290 5300
LKGPAIGGAL PGISIQGPEG NLQMPGIKAS GCDVKLSSGQ ISGPEIKGDL
5310 5320 5330 5340 5350
KGSGLGLHGA VPDIGVKGPS FNVASPESDF GVSLKGPKVK GGVDVSGGVS
5360 5370 5380 5390 5400
VPDINLGEGH MSVKGSGVEW KGPQVSSSLN LDTSKLAGNL HFSGPKIEGD
5410 5420 5430 5440 5450
VKGGQTGLQG PGLSVSGPQG HLESESGKVT FPKMKIPKFT FSGRELIGRE
5460 5470 5480 5490 5500
VGVDVNFPKV EANVQAGAGE GKWEESEVKL KKSKIKMPKH IFSKSKGKGG
5510 5520 5530 5540 5550
VTGSPEASIS GSKGDLKSSK ASLGSLEGEV EAEASSPKGK FSLFKSKKPR
5560 5570 5580 5590 5600
HRSNSFSDER EFSAPSTPTG TLEFAGGDAK GKHGKLKFGT FGGLGSKSKG
5610 5620 5630 5640 5650
HYEVTGSDDE AGKLQGSGVS LASKKSRLSS SSSNDSGTKV GIQLPEVELS

VSTKKE
Length:5,656
Mass (Da):604,253
Last modified:April 5, 2011 - v1
Checksum:i5C0B75977620DBD4
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
G5E8K8G5E8K8_MOUSE
AHNAK nucleoprotein (desmoyokin)
Ahnak mCG_17833
150Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC130819 Genomic DNA No translation available.
RefSeqiNP_033773.1, NM_009643.2
XP_006527316.1, XM_006527253.3
UniGeneiMm.203866
Mm.392302

Genome annotation databases

EnsembliENSMUST00000092956; ENSMUSP00000090633; ENSMUSG00000069833
GeneIDi66395
UCSCiuc008goj.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC130819 Genomic DNA No translation available.
RefSeqiNP_033773.1, NM_009643.2
XP_006527316.1, XM_006527253.3
UniGeneiMm.203866
Mm.392302

3D structure databases

ProteinModelPortaliE9Q616
SMRiE9Q616
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

ComplexPortaliCPX-905 AHNAK - Annexin A2 - S100-A10 complex
IntActiE9Q616, 1 interactor
STRINGi10090.ENSMUSP00000090633

PTM databases

iPTMnetiE9Q616
PhosphoSitePlusiE9Q616

Proteomic databases

MaxQBiE9Q616
PaxDbiE9Q616
PeptideAtlasiE9Q616
PRIDEiE9Q616

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000092956; ENSMUSP00000090633; ENSMUSG00000069833
GeneIDi66395
UCSCiuc008goj.2 mouse

Organism-specific databases

CTDi79026
MGIiMGI:1316648 Ahnak

Phylogenomic databases

eggNOGiENOG410IGIF Eukaryota
ENOG410XQS3 LUCA
GeneTreeiENSGT00530000063716
InParanoidiE9Q616
OMAiINAPHGK
OrthoDBiEOG091G01FG
TreeFamiTF350595

Miscellaneous databases

ChiTaRSiAhnak mouse
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000069833 Expressed in 284 organ(s), highest expression level in urinary bladder
ExpressionAtlasiE9Q616 baseline and differential
GenevisibleiE9Q616 MM

Family and domain databases

InterProiView protein in InterPro
IPR001478 PDZ
IPR036034 PDZ_sf
SMARTiView protein in SMART
SM00228 PDZ, 1 hit
SUPFAMiSSF50156 SSF50156, 1 hit
PROSITEiView protein in PROSITE
PS50106 PDZ, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE9Q616_MOUSE
AccessioniPrimary (citable) accession number: E9Q616
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: November 7, 2018
This is version 60 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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