Olfr414

Functionⁱ

GO - Molecular functionⁱ

G-protein coupled receptor activity Source: UniProtKB-KW
olfactory receptor activity
Source: MGI
Inferred from sequence alignmentⁱ
- 14611657

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

G-protein coupled receptor signaling pathway
Source: MGI
Inferred from sequence alignmentⁱ
- 14611657
sensory perception of smell
Source: MGI
Inferred from sequence alignmentⁱ
- 14611657

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	G-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer
Biological process	OlfactionUniRule annotationSAAS annotation, Sensory transduction

Enzyme and pathway databases

Reactomeⁱ	R-MMU-381753 Olfactory Signaling Pathway

Reactomeⁱ

R-MMU-381753 Olfactory Signaling Pathway

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Olfactory receptorUniRule annotation
Gene namesⁱ	Name:Olfr414Imported
Organismⁱ	Mus musculus (Mouse)Imported
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 1

Organism-specific databases

MGIⁱ	MGI:3030248 Olfr414

Topology

Feature key	Position(s)	DescriptionActions	Length
Transmembraneⁱ	25 – 52	HelicalUniRule annotationAdd BLAST	28
Transmembraneⁱ	59 – 81	HelicalUniRule annotationAdd BLAST	23
Transmembraneⁱ	101 – 120	HelicalUniRule annotationAdd BLAST	20
Transmembraneⁱ	140 – 162	HelicalUniRule annotationAdd BLAST	23
Transmembraneⁱ	200 – 225	HelicalUniRule annotationAdd BLAST	26
Transmembraneⁱ	237 – 253	HelicalUniRule annotationAdd BLAST	17
Transmembraneⁱ	273 – 292	HelicalUniRule annotationAdd BLAST	20

Keywords - Cellular componentⁱ

Cell membraneUniRule annotationSAAS annotation, Membrane

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSMUSG00000051509 Expressed in 1 organ(s), highest expression level in spleen

Bgeeⁱ

ENSMUSG00000051509 Expressed in 1 organ(s), highest expression level in spleen

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	10090.ENSMUSP00000052426

STRINGⁱ

10090.ENSMUSP00000052426

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	41 – 290	G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST		250

Sequence similaritiesⁱ

Belongs to the G-protein coupled receptor 1 family.UniRule annotationSAAS annotation

Keywords - Domainⁱ

Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGⁱ	ENOG410ING1 Eukaryota ENOG41116BH LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00800000124041
KEGG Orthology (KO) More...KOⁱ	K04257
OMAⁱ	RAMYTFN
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0AZH
TreeFamⁱ	TF337475

Family and domain databases

InterProⁱ	View protein in InterPro IPR000276 GPCR_Rhodpsn IPR017452 GPCR_Rhodpsn_7TM IPR000725 Olfact_rcpt
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF13853 7tm_4, 1 hit
PRINTSⁱ	PR00237 GPCRRHODOPSN PR00245 OLFACTORYR
PROSITEⁱ	View protein in PROSITE PS00237 G_PROTEIN_RECEP_F1_1, 1 hit PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

E9Q5P8-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MRNLSGSHVE EFVLVGFPTS RPFQALLFVF FFAIYLLTLL ENVLIVSTIW 
        60         70         80         90        100
LTPSLHRPMY FFLGHLSFLE LWYINVTIPR LLGAFLTQDG RVSYGGCMTQ 
       110        120        130        140        150
LYFFIALACT ECVLLAVMAY DRYLAICEPL RYPSLMPPRL ATRLAAASWG 
       160        170        180        190        200
SGFFSSMMKL LFISRLSYCG PNIINHFFCD ISPLLNLTCS DKEQAELVDF 
       210        220        230        240        250
LLALVMILLP LVAVVSSYAA IIVAILRIPT AQGRHKAFST CTSHLAVVVI 
       260        270        280        290        300
YYSSTLFTYA RPRAMYTFNY NKIISVLYTV IVPFLNPAIY CLRNKEVKDA 
       310 
FRKTVLGRCH HPREGPD

Length:317

Mass (Da):35,943

Last modified:April 5, 2011 - v1

Checksum:ⁱ981ECD74168D7B3C

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC113056 Genomic DNA No translation available.
NCBI Reference Sequences More...RefSeqⁱ	NP_666972.2, NM_146761.2
UniGeneⁱ	Mm.223188

Genome annotation databases

Ensemblⁱ	ENSMUST00000053178; ENSMUSP00000052426; ENSMUSG00000051509 ENSMUST00000192358; ENSMUSP00000142051; ENSMUSG00000051509
GeneIDⁱ	258756
KEGGⁱ	mmu:258756
UCSC genome browser More...UCSCⁱ	uc007dtb.2 mouse

Similar proteinsⁱ

90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
E9Q5P8	Olfactory receptor		TUPCH		317	UniRef90_E9Q5P8
Olfactory receptor		OTOGA		317
Olfactory receptor		MOUSE		317
Olfactory receptor		FUKDA		317
Olfactory receptor		MESAU		317
+6

Protein	Similar proteins		Species	Score	Length	Source
E9Q5P8	Olfactory receptor		RAT		317	UniRef50_D4A0A9
Olfactory receptor		Florida manatee		317
Olfactory receptor		LOXAF		317
Olfactory receptor		DIPOR		317
Olfactory receptor		CRIGR		317
+28

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC113056 Genomic DNA No translation available.
RefSeqⁱ	NP_666972.2, NM_146761.2
UniGeneⁱ	Mm.223188

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10090.ENSMUSP00000052426

STRINGⁱ

10090.ENSMUSP00000052426

Protein family/group databases

GPCRDBⁱ	Search...

GPCRDBⁱ

Search...

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000053178; ENSMUSP00000052426; ENSMUSG00000051509 ENSMUST00000192358; ENSMUSP00000142051; ENSMUSG00000051509
GeneIDⁱ	258756
KEGGⁱ	mmu:258756
UCSCⁱ	uc007dtb.2 mouse

Organism-specific databases

CTDⁱ	258756
MGIⁱ	MGI:3030248 Olfr414

Phylogenomic databases

eggNOGⁱ	ENOG410ING1 Eukaryota ENOG41116BH LUCA
GeneTreeⁱ	ENSGT00800000124041
KOⁱ	K04257
OMAⁱ	RAMYTFN
OrthoDBⁱ	EOG091G0AZH
TreeFamⁱ	TF337475

Enzyme and pathway databases

Reactomeⁱ	R-MMU-381753 Olfactory Signaling Pathway

Reactomeⁱ

R-MMU-381753 Olfactory Signaling Pathway

Miscellaneous databases

SOURCEⁱ	Search...

SOURCEⁱ

Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000051509 Expressed in 1 organ(s), highest expression level in spleen

Bgeeⁱ

ENSMUSG00000051509 Expressed in 1 organ(s), highest expression level in spleen

Family and domain databases

InterProⁱ	View protein in InterPro IPR000276 GPCR_Rhodpsn IPR017452 GPCR_Rhodpsn_7TM IPR000725 Olfact_rcpt
Pfamⁱ	View protein in Pfam PF13853 7tm_4, 1 hit
PRINTSⁱ	PR00237 GPCRRHODOPSN PR00245 OLFACTORYR
PROSITEⁱ	View protein in PROSITE PS00237 G_PROTEIN_RECEP_F1_1, 1 hit PS50262 G_PROTEIN_RECEP_F1_2, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	E9Q5P8_MOUSE
Accessionⁱ	E9Q5P8Primary (citable) accession number: E9Q5P8
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	April 5, 2011
	Last sequence update:	April 5, 2011
	Last modified:	September 12, 2018
	This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - E9Q5P8 (E9Q5P8_MOUSE)

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Olfactory receptor

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Plasma membrane

Plasma Membrane

Other locations

Topology

Keywords - Cellular componenti

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protein family/group databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Expressionⁱ

Interactionⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ