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Protein
Submitted name:

Neural cell adhesion molecule 1

Gene

Ncam1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-MMU-375165 NCAM signaling for neurite out-growth
R-MMU-419037 NCAM1 interactions
R-MMU-445144 Signal transduction by L1
R-MMU-5673001 RAF/MAP kinase cascade

Names & Taxonomyi

Protein namesi
Submitted name:
Neural cell adhesion molecule 1Imported
Gene namesi
Name:Ncam1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 9

Organism-specific databases

MGIiMGI:97281 Ncam1

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_500324573920 – 725Sequence analysisAdd BLAST706

Proteomic databases

MaxQBiE9Q589
PeptideAtlasiE9Q589
PRIDEiE9Q589

Expressioni

Gene expression databases

BgeeiENSMUSG00000039542
ExpressionAtlasiE9Q589 baseline and differential
GenevisibleiE9Q589 MM

Structurei

3D structure databases

ProteinModelPortaliE9Q589
SMRiE9Q589
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini20 – 111Ig-likeInterPro annotationAdd BLAST92
Domaini116 – 189Ig-likeInterPro annotationAdd BLAST74
Domaini212 – 302Ig-likeInterPro annotationAdd BLAST91
Domaini309 – 404Ig-likeInterPro annotationAdd BLAST96
Domaini407 – 492Ig-likeInterPro annotationAdd BLAST86
Domaini500 – 599Fibronectin type-IIIInterPro annotationAdd BLAST100
Domaini601 – 696Fibronectin type-IIIInterPro annotationAdd BLAST96

Keywords - Domaini

RepeatSAAS annotation, SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IQJI Eukaryota
ENOG410XTGB LUCA
GeneTreeiENSGT00910000144011

Family and domain databases

CDDicd00063 FN3, 2 hits
Gene3Di2.60.40.10, 7 hits
InterProiView protein in InterPro
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR013098 Ig_I-set
IPR003599 Ig_sub
IPR003598 Ig_sub2
IPR013106 Ig_V-set
IPR033019 Ncam1
IPR009138 Neural_cell_adh
PANTHERiPTHR44059:SF2 PTHR44059:SF2, 1 hit
PfamiView protein in Pfam
PF00041 fn3, 2 hits
PF07679 I-set, 3 hits
PRINTSiPR01838 NCAMFAMILY
SMARTiView protein in SMART
SM00060 FN3, 2 hits
SM00409 IG, 5 hits
SM00408 IGc2, 5 hits
SM00406 IGv, 2 hits
SUPFAMiSSF48726 SSF48726, 5 hits
SSF49265 SSF49265, 1 hit
PROSITEiView protein in PROSITE
PS50853 FN3, 2 hits
PS50835 IG_LIKE, 5 hits

Sequencei

Sequence statusi: Complete.

E9Q589-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLRTKDLIWT LFFLGTAVSL QVDIVPSQGE ISVGESKFFL CQVAGDAKDK
60 70 80 90 100
DISWFSPNGE KLSPNQQRIS VVWNDDDSST LTIYNANIDD AGIYKCVVTA
110 120 130 140 150
EDGTQSEATV NVKIFQKLMF KNAPTPQEFK EGEDAVIVCD VVSSLPPTII
160 170 180 190 200
WKHKGRDVIL KKDVRFIVLS NNYLQIRGIK KTDEGTYRCE GRILARGEIN
210 220 230 240 250
FKDIQVIVNV PPTVQARQSI VNATANLGQS VTLVCDADGF PEPTMSWTKD
260 270 280 290 300
GEPIENEEED DEKHIFSDDS SELTIRNVDK NDEAEYVCIA ENKAGEQDAS
310 320 330 340 350
IHLKVFAKPK ITYVENQTAM ELEEQVTLTC EASGDPIPSI TWRTSTRNIS
360 370 380 390 400
SEEKTLDGHM VVRSHARVSS LTLKSIQYTD AGEYICTASN TIGQDSQSMY
410 420 430 440 450
LEVQYAPKLQ GPVAVYTWEG NQVNITCEVF AYPSATISWF RDGQLLPSSN
460 470 480 490 500
YSNIKIYNTP SASYLEVTPD SENDFGNYNC TAVNRIGQES LEFILVQADT
510 520 530 540 550
PSSPSIDRVE PYSSTAQVQF DEPEATGGVP ILKYKAEWKS LGEESWHFKW
560 570 580 590 600
YDAKEANMEG IVTIMGLKPE TRYSVRLAAL NGKGLGEISA ATEFKTQPVR
610 620 630 640 650
EPSAPKLEGQ MGEDGNSIKV NLIKQDDGGS PIRHYLVKYR ALASEWKPEI
660 670 680 690 700
RLPSGSDHVM LKSLDWNAEY EVYVVAENQQ GKSKAAHFVF RTSAQPTAIP
710 720
ATLGGSSTSY TLVSLLFSAV TLLLL
Length:725
Mass (Da):80,358
Last modified:April 5, 2011 - v1
Checksum:iE08F947CD65FF22C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC117630 Genomic DNA No translation available.
AC140447 Genomic DNA No translation available.
CT025676 Genomic DNA No translation available.
RefSeqiNP_035005.2, NM_010875.3
UniGeneiMm.439182
Mm.4974

Genome annotation databases

EnsembliENSMUST00000114476; ENSMUSP00000110120; ENSMUSG00000039542
GeneIDi17967
UCSCiuc009pjh.1 mouse

Similar proteinsi

Entry informationi

Entry nameiE9Q589_MOUSE
AccessioniPrimary (citable) accession number: E9Q589
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: March 28, 2018
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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