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Protein
Submitted name:

Kinesin family member 13B

Gene

Kif13b

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi103 – 110ATPPROSITE-ProRule annotation8

GO - Molecular functioni

  • 14-3-3 protein binding Source: MGI
  • ATPase activity Source: GO_Central
  • ATP binding Source: UniProtKB-UniRule
  • microtubule binding Source: GO_Central
  • microtubule motor activity Source: GO_Central
  • protein kinase binding Source: MGI

GO - Biological processi

Keywordsi

Molecular functionMotor proteinPROSITE-ProRule annotation
LigandATP-bindingPROSITE-ProRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-MMU-6811434 COPI-dependent Golgi-to-ER retrograde traffic
R-MMU-983189 Kinesins

Names & Taxonomyi

Protein namesi
Submitted name:
Kinesin family member 13BImported
Gene namesi
Name:Kif13bImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 14

Organism-specific databases

MGIiMGI:1098265 Kif13b

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

MaxQBiE9Q4K7
PaxDbiE9Q4K7
PeptideAtlasiE9Q4K7
PRIDEiE9Q4K7

PTM databases

iPTMnetiE9Q4K7
PhosphoSitePlusiE9Q4K7

Expressioni

Gene expression databases

BgeeiENSMUSG00000060012 Expressed in 92 organ(s), highest expression level in cerebellum
ExpressionAtlasiE9Q4K7 baseline and differential
GenevisibleiE9Q4K7 MM

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
Dlg1Q626962EBI-9085496,EBI-389325From Rattus norvegicus.

GO - Molecular functioni

Protein-protein interaction databases

DIPiDIP-61928N
IntActiE9Q4K7, 29 interactors
MINTiE9Q4K7
STRINGi10090.ENSMUSP00000098041

Structurei

3D structure databases

ProteinModelPortaliE9Q4K7
SMRiE9Q4K7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 353Kinesin motorInterPro annotationAdd BLAST349
Domaini1737 – 1779CAP-GlyInterPro annotationAdd BLAST43

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili368 – 388Sequence analysisAdd BLAST21
Coiled coili623 – 643Sequence analysisAdd BLAST21
Coiled coili669 – 689Sequence analysisAdd BLAST21
Coiled coili753 – 773Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.PROSITE-ProRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0245 Eukaryota
COG5059 LUCA
GeneTreeiENSGT00930000150817
InParanoidiE9Q4K7
KOiK17914
OMAiFCKYNFW
OrthoDBiEOG091G0091
TreeFamiTF105221

Family and domain databases

CDDicd00060 FHA, 1 hit
Gene3Di2.30.30.190, 1 hit
3.40.850.10, 1 hit
InterProiView protein in InterPro
IPR036859 CAP-Gly_dom_sf
IPR000938 CAP-Gly_domain
IPR000253 FHA_dom
IPR036978 KIF13B
IPR022164 Kinesin-like
IPR027640 Kinesin-like_fam
IPR022140 Kinesin-like_KIF1-typ
IPR032405 Kinesin_assoc
IPR019821 Kinesin_motor_CS
IPR001752 Kinesin_motor_dom
IPR036961 Kinesin_motor_dom_sf
IPR027417 P-loop_NTPase
IPR008984 SMAD_FHA_dom_sf
PANTHERiPTHR24115 PTHR24115, 1 hit
PTHR24115:SF746 PTHR24115:SF746, 1 hit
PfamiView protein in Pfam
PF01302 CAP_GLY, 1 hit
PF12473 DUF3694, 1 hit
PF00498 FHA, 1 hit
PF12423 KIF1B, 1 hit
PF00225 Kinesin, 1 hit
PF16183 Kinesin_assoc, 1 hit
PRINTSiPR00380 KINESINHEAVY
SMARTiView protein in SMART
SM01052 CAP_GLY, 1 hit
SM00129 KISc, 1 hit
SUPFAMiSSF49879 SSF49879, 1 hit
SSF52540 SSF52540, 1 hit
SSF74924 SSF74924, 1 hit
PROSITEiView protein in PROSITE
PS00845 CAP_GLY_1, 1 hit
PS50245 CAP_GLY_2, 1 hit
PS00411 KINESIN_MOTOR_1, 1 hit
PS50067 KINESIN_MOTOR_2, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

E9Q4K7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGDSKVKVAV RVRPMNRREI DLHTKCVVDV EANKVILNPV NTNLSKGDAR
60 70 80 90 100
GQPKIFAYDH CFWSMDESVR EKYAGQEDVF KCLGENILQN AFDGYNACIF
110 120 130 140 150
AYGQTGSGKS YTMMGTADQP GLIPRLCSGL FERTQKEENE EQSFKVEVSY
160 170 180 190 200
MEIYNEKVRD LLDPKGSRQT LKVREHSVLG PYVDGLSKLA VTSYKDIESL
210 220 230 240 250
MSEGNKSRTV AATNMNEESS RSHAVFKITL THTLYDVKSG TSGEKVGKLS
260 270 280 290 300
LVDLAGSERA TKTGAAGDRL KEGSNINKSL TTLGLVISAL ADQGAGKNKN
310 320 330 340 350
KFVPYRDSVL TWLLKDSLGG NSKTAMVATV SPAADNYDET LSTLRYADRA
360 370 380 390 400
KHIVNHAVVN EDPNARIIRD LREEVEKLRE QLTKAEAMKS PELKDRLEES
410 420 430 440 450
EKLIQEMTVT WEEKLRKTEE IAQERQKQLE SLGISLQTSG IKVGDDKCFL
460 470 480 490 500
VNLNADPALN ELLVYYLKEH TLIGSANSQD IQLCGMGILP EHGIIDITPE
510 520 530 540 550
GQVVLTPQKN TRTFVNGSSV SSPIQLHHGD RILWGNNHFF RLNLPKKKKK
560 570 580 590 600
AEREDEDREA SLKNDSSSEQ LDADGDSSSE VSSEINFNFE YAQMEVTMKA
610 620 630 640 650
LGSNDPMQSI LSSLEQQHEE EKRSALERQR LMYEHELEQL RRRLSPERQN
660 670 680 690 700
CRGVDRLSFH SPSAQQRLKQ WAEEREATLN NSLMRLREQI VKANLLVREA
710 720 730 740 750
SYIAEELDKR TEYKVTLQIP TSSLDANRKR GSLLSEPAIQ VRRKGKGKQI
760 770 780 790 800
WSLEKLENRL LDMRDLYQEW KECEEDSPVS RSYFKRADPF YDEQENHSLI
810 820 830 840 850
GVANVFLETL FYDVKLQYAV PIINQKGEVA GRLHVEVMRL SGAIGERIAG
860 870 880 890 900
GDDPTEVSSE KEAQENRLVC MVKILQATGL PQHLCHFVFC KYDFWDQQEP
910 920 930 940 950
VTVAPEVDTS SSPTSKQPQC MVVFDHCSEF SVNITEDFIE YLSEGALAIE
960 970 980 990 1000
VYGHKMNDPR KNPALWDLGI IQAKTRSLRD RWSEVTRKLE FWVQILEQNE
1010 1020 1030 1040 1050
NGDYCPVEVI AAKDVPTGGI FQLRQGQSRR VQVEVKSVQE SGTLPLMEEC
1060 1070 1080 1090 1100
ILSVGIGCVK VRPLRSPKIH ENVHEEEEDM DSYQDRDLER LRRKWLNALT
1110 1120 1130 1140 1150
KRQEYLDQQL QKLVSKHDKT EDDADREAQL LEMRLTLTEE RNAVMVPSAG
1160 1170 1180 1190 1200
SGIPGAPAEW TPVPGMETHI PVIFLDLNAD DFSSQDNLDD PEAGWDATLT
1210 1220 1230 1240 1250
GEEEEEFFEL QIVKQHDGEV KAEASWDSAV HSCPQLSKGT PADERVFLIL
1260 1270 1280 1290 1300
RVTVQLSHPA DMQLVLRKRI CVHVHGRQGF AQSLLKKMSH RSSIPGCGVT
1310 1320 1330 1340 1350
FEIVSNIPED AQGVEEREAL ARMAANVENP ASADSEAYIE KYLRSVLAVE
1360 1370 1380 1390 1400
NLLTLDRLRQ EVAVKEQLTG KGKLSRRSIS SPSMNRLSGS RQELSPSHSL
1410 1420 1430 1440 1450
GSNKGRWESQ QDVSQTLVSR GIAPGPPALS VSPQNNQSPD PGLGGVAASY
1460 1470 1480 1490 1500
LNPVKSLVPQ MPKLLKSLFP VRDDRRGRHS SPLAHQPVPR ILVQPTFSDT
1510 1520 1530 1540 1550
WATRTEEVSH QVGAAPLAEV MAAPAVKICD KPVKVSSPPS PMVVTQPPEG
1560 1570 1580 1590 1600
QDGPPSPLSE ASSGYFSHSV SSATLSETLT LGLDTTGLGS QTPGSPPALC
1610 1620 1630 1640 1650
QVTPEPELAF LSCTQSHPPA PEEAHVPAAP TQSTELEVPR APLLSEPASA
1660 1670 1680 1690 1700
VPTSPFRIRK VRTSELKSFT GMLGGASSGA EEDPLASEDP SNARGQTLGR
1710 1720 1730 1740 1750
LEVTSDSEDA SEVPEWLREG EYVVVGTNKT GIVRYIGPTD FQEGTWIGVE
1760 1770 1780 1790 1800
LDLPAGKNDG SIGGKQYFRC NPGYGLLVRP SRVRRAVGTG RRRSSGLQPQ
1810 1820 1830 1840
GAPEVRRSAT ISGSATNLAS LTAALAKGDR SYKNPENRKS WAS
Length:1,843
Mass (Da):204,575
Last modified:April 5, 2011 - v1
Checksum:i189721AB9ED0ACFA
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A286YCV9A0A286YCV9_MOUSE
Kinesin family member 13B
Kif13b
1,847Annotation score:
A0A286YD28A0A286YD28_MOUSE
Kinesin family member 13B
Kif13b
151Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC105979 Genomic DNA No translation available.
AC132602 Genomic DNA No translation available.
RefSeqiNP_001074646.1, NM_001081177.1
UniGeneiMm.23611

Genome annotation databases

EnsembliENSMUST00000100473; ENSMUSP00000098041; ENSMUSG00000060012
GeneIDi16554
KEGGimmu:16554
UCSCiuc007uim.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC105979 Genomic DNA No translation available.
AC132602 Genomic DNA No translation available.
RefSeqiNP_001074646.1, NM_001081177.1
UniGeneiMm.23611

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5B64X-ray2.70B677-798[»]
ProteinModelPortaliE9Q4K7
SMRiE9Q4K7
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-61928N
IntActiE9Q4K7, 29 interactors
MINTiE9Q4K7
STRINGi10090.ENSMUSP00000098041

PTM databases

iPTMnetiE9Q4K7
PhosphoSitePlusiE9Q4K7

Proteomic databases

MaxQBiE9Q4K7
PaxDbiE9Q4K7
PeptideAtlasiE9Q4K7
PRIDEiE9Q4K7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000100473; ENSMUSP00000098041; ENSMUSG00000060012
GeneIDi16554
KEGGimmu:16554
UCSCiuc007uim.1 mouse

Organism-specific databases

CTDi23303
MGIiMGI:1098265 Kif13b

Phylogenomic databases

eggNOGiKOG0245 Eukaryota
COG5059 LUCA
GeneTreeiENSGT00930000150817
InParanoidiE9Q4K7
KOiK17914
OMAiFCKYNFW
OrthoDBiEOG091G0091
TreeFamiTF105221

Enzyme and pathway databases

ReactomeiR-MMU-6811434 COPI-dependent Golgi-to-ER retrograde traffic
R-MMU-983189 Kinesins

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000060012 Expressed in 92 organ(s), highest expression level in cerebellum
ExpressionAtlasiE9Q4K7 baseline and differential
GenevisibleiE9Q4K7 MM

Family and domain databases

CDDicd00060 FHA, 1 hit
Gene3Di2.30.30.190, 1 hit
3.40.850.10, 1 hit
InterProiView protein in InterPro
IPR036859 CAP-Gly_dom_sf
IPR000938 CAP-Gly_domain
IPR000253 FHA_dom
IPR036978 KIF13B
IPR022164 Kinesin-like
IPR027640 Kinesin-like_fam
IPR022140 Kinesin-like_KIF1-typ
IPR032405 Kinesin_assoc
IPR019821 Kinesin_motor_CS
IPR001752 Kinesin_motor_dom
IPR036961 Kinesin_motor_dom_sf
IPR027417 P-loop_NTPase
IPR008984 SMAD_FHA_dom_sf
PANTHERiPTHR24115 PTHR24115, 1 hit
PTHR24115:SF746 PTHR24115:SF746, 1 hit
PfamiView protein in Pfam
PF01302 CAP_GLY, 1 hit
PF12473 DUF3694, 1 hit
PF00498 FHA, 1 hit
PF12423 KIF1B, 1 hit
PF00225 Kinesin, 1 hit
PF16183 Kinesin_assoc, 1 hit
PRINTSiPR00380 KINESINHEAVY
SMARTiView protein in SMART
SM01052 CAP_GLY, 1 hit
SM00129 KISc, 1 hit
SUPFAMiSSF49879 SSF49879, 1 hit
SSF52540 SSF52540, 1 hit
SSF74924 SSF74924, 1 hit
PROSITEiView protein in PROSITE
PS00845 CAP_GLY_1, 1 hit
PS50245 CAP_GLY_2, 1 hit
PS00411 KINESIN_MOTOR_1, 1 hit
PS50067 KINESIN_MOTOR_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE9Q4K7_MOUSE
AccessioniPrimary (citable) accession number: E9Q4K7
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: November 7, 2018
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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