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Protein
Submitted name:

Kelch-like 18

Gene

Klhl18

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Kelch-like 18Imported
Gene namesi
Name:Klhl18Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 9

Organism-specific databases

MGIiMGI:2143315 Klhl18

PTM / Processingi

Proteomic databases

MaxQBiE9Q4F2
PaxDbiE9Q4F2
PRIDEiE9Q4F2

Expressioni

Gene expression databases

BgeeiENSMUSG00000054792 Expressed in 221 organ(s), highest expression level in retina
ExpressionAtlasiE9Q4F2 baseline and differential
GenevisibleiE9Q4F2 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000069674

Structurei

3D structure databases

ProteinModelPortaliE9Q4F2
SMRiE9Q4F2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini38 – 105BTBInterPro annotationAdd BLAST68

Keywords - Domaini

Kelch repeatSAAS annotation, RepeatSAAS annotation

Phylogenomic databases

eggNOGiKOG4441 Eukaryota
ENOG410XNX8 LUCA
GeneTreeiENSGT00760000118931
TreeFamiTF329218

Family and domain databases

Gene3Di2.120.10.80, 2 hits
InterProiView protein in InterPro
IPR011705 BACK
IPR017096 BTB-kelch_protein
IPR000210 BTB/POZ_dom
IPR015915 Kelch-typ_b-propeller
IPR006652 Kelch_1
IPR011333 SKP1/BTB/POZ_sf
PfamiView protein in Pfam
PF07707 BACK, 1 hit
PF00651 BTB, 1 hit
PF01344 Kelch_1, 6 hits
PIRSFiPIRSF037037 Kelch-like_protein_gigaxonin, 1 hit
SMARTiView protein in SMART
SM00875 BACK, 1 hit
SM00225 BTB, 1 hit
SM00612 Kelch, 6 hits
SUPFAMiSSF117281 SSF117281, 2 hits
SSF54695 SSF54695, 1 hit
PROSITEiView protein in PROSITE
PS50097 BTB, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

E9Q4F2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVEDGAEELE DLVHFSVSEL PSRGYGVMEE IRRQGKLCDV TLKIGDHKFS
60 70 80 90 100
AHRIVLAASI PYFHAMFTND MMECKQDEIV MQGMDPSALE ALINFAYNGN
110 120 130 140 150
LAIDQQNVQS LLMGASFLQL QSIKDACCTF LRERLHPKNC LGVRQFAETM
160 170 180 190 200
MCAVLYDAAN SFIHQHFVEV SLSEEFLALP LEDVLELVSR DELNVKSEEQ
210 220 230 240 250
VFEAALAWVR YDREQRGPCL PELLSNIRLP LCRPQFLSDR VQQDDLVRCC
260 270 280 290 300
HKCRDLVDEA KDYHLMPERR PHLPAFRTRP RCCTSIAGLI YAVGGLNSAG
310 320 330 340 350
DSLNVVEVFD PIANRWEKCH PMTTARSRVG VAVVNGLLYA IGGYDGQLRL
360 370 380 390 400
STVEAYNPET DTWTRVGSMN SKRSAMGTVV LDGQIYVCGG YDGNSSLNSV
410 420 430 440 450
ETYSPETDKW TVVTPMSSNR SAAGVTVFEG RIYVSGGHDG LQIFSSVEHY
460 470 480 490 500
NHHTATWHPA ASMLNKRCRH GAASLGSKMF VCGGYDGSGF LSIAEMYSSV
510 520 530 540 550
ADQWCLIVPM HTRRSRVSLV ASCGRLYAVG GYDGQSNLSS VEMYDPETDR
560 570
WTFMAPMACH EGGVGVGCIP LLTI
Length:574
Mass (Da):63,686
Last modified:April 5, 2011 - v1
Checksum:i5C2D5F5F55ECFC5A
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0G2JGN5A0A0G2JGN5_MOUSE
Kelch-like 18
Klhl18
579Annotation score:
A0A0G2JG13A0A0G2JG13_MOUSE
Kelch-like 18
Klhl18
509Annotation score:
A0A0G2JGV8A0A0G2JGV8_MOUSE
Kelch-like 18
Klhl18
197Annotation score:
A0A0G2JEL8A0A0G2JEL8_MOUSE
Kelch-like 18
Klhl18
216Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC132103 Genomic DNA No translation available.
AC160104 Genomic DNA No translation available.
RefSeqiNP_808439.2, NM_177771.5
UniGeneiMm.41744

Genome annotation databases

EnsembliENSMUST00000068025; ENSMUSP00000069674; ENSMUSG00000054792
GeneIDi270201
UCSCiuc009rua.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC132103 Genomic DNA No translation available.
AC160104 Genomic DNA No translation available.
RefSeqiNP_808439.2, NM_177771.5
UniGeneiMm.41744

3D structure databases

ProteinModelPortaliE9Q4F2
SMRiE9Q4F2
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000069674

Proteomic databases

MaxQBiE9Q4F2
PaxDbiE9Q4F2
PRIDEiE9Q4F2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000068025; ENSMUSP00000069674; ENSMUSG00000054792
GeneIDi270201
UCSCiuc009rua.1 mouse

Organism-specific databases

CTDi23276
MGIiMGI:2143315 Klhl18

Phylogenomic databases

eggNOGiKOG4441 Eukaryota
ENOG410XNX8 LUCA
GeneTreeiENSGT00760000118931
TreeFamiTF329218

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000054792 Expressed in 221 organ(s), highest expression level in retina
ExpressionAtlasiE9Q4F2 baseline and differential
GenevisibleiE9Q4F2 MM

Family and domain databases

Gene3Di2.120.10.80, 2 hits
InterProiView protein in InterPro
IPR011705 BACK
IPR017096 BTB-kelch_protein
IPR000210 BTB/POZ_dom
IPR015915 Kelch-typ_b-propeller
IPR006652 Kelch_1
IPR011333 SKP1/BTB/POZ_sf
PfamiView protein in Pfam
PF07707 BACK, 1 hit
PF00651 BTB, 1 hit
PF01344 Kelch_1, 6 hits
PIRSFiPIRSF037037 Kelch-like_protein_gigaxonin, 1 hit
SMARTiView protein in SMART
SM00875 BACK, 1 hit
SM00225 BTB, 1 hit
SM00612 Kelch, 6 hits
SUPFAMiSSF117281 SSF117281, 2 hits
SSF54695 SSF54695, 1 hit
PROSITEiView protein in PROSITE
PS50097 BTB, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE9Q4F2_MOUSE
AccessioniPrimary (citable) accession number: E9Q4F2
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: September 12, 2018
This is version 65 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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