Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
We will be switching to the new UniProt website soon. Please explore and share your feedback. Take me to the new website.

UniProtKB - E9Q447 (E9Q447_MOUSE)

Entry version 84 (19 Jan 2022)
Sequence version 1 (05 Apr 2011)
Previous versions | rss
Add a publicationFeedback
Protein
Submitted name:

Spectrin alpha chain, non-erythrocytic 1

Gene

Sptan1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) of the calcium-binding region(s) within the protein. One common calcium-binding motif is the EF-hand, but other calcium-binding motifs also exist.<p><a href='/help/ca_bind' target='_top'>More...</a></p>Calcium bindingi2342 – 2353PROSITE-ProRule annotationAdd BLAST12
Calcium bindingi2385 – 2396PROSITE-ProRule annotationAdd BLAST12

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActin cappingARBA annotation, Actin-bindingARBA annotation, Calmodulin-bindingARBA annotation
LigandCalciumPROSITE-ProRule annotationARBA annotation, Metal-bindingPROSITE-ProRule annotationARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Spectrin alpha chain, non-erythrocytic 1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Sptan1Imported
Synonyms:Spna2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...MGIi		MGI:98386, Sptan1

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSMUSG00000057738

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

CytoplasmARBA annotation

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		E9Q447

MaxQB - The MaxQuant DataBase

More...MaxQBi		E9Q447

PeptideAtlas

More...PeptideAtlasi		E9Q447

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		314666

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		E9Q447

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSMUSG00000057738, Expressed in facial nucleus and 328 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		E9Q447, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		E9Q447, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Complete GO annotation on QuickGO ...

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		E9Q447

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini967 – 1026SH3InterPro annotationAdd BLAST60
Domaini2329 – 2364EF-handInterPro annotationAdd BLAST36
Domaini2372 – 2407EF-handInterPro annotationAdd BLAST36

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili184 – 204Sequence analysisAdd BLAST21
Coiled coili290 – 324Sequence analysisAdd BLAST35
Coiled coili386 – 416Sequence analysisAdd BLAST31
Coiled coili502 – 522Sequence analysisAdd BLAST21
Coiled coili614 – 634Sequence analysisAdd BLAST21
Coiled coili713 – 733Sequence analysisAdd BLAST21
Coiled coili858 – 889Sequence analysisAdd BLAST32
Coiled coili1106 – 1140Sequence analysisAdd BLAST35
Coiled coili1248 – 1268Sequence analysisAdd BLAST21
Coiled coili1678 – 1712Sequence analysisAdd BLAST35
Coiled coili2157 – 2189Sequence analysisAdd BLAST33

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the spectrin family.ARBA annotation

Keywords - Domaini

Coiled coilSequence analysis, RepeatARBA annotation, SH3 domainPROSITE-ProRule annotationARBA annotation

Phylogenomic databases

Ensembl GeneTree

More...GeneTreei		ENSGT00940000156662

Database for complete collections of gene phylogenies

More...PhylomeDBi		E9Q447

Family and domain databases

Conserved Domains Database

More...CDDi		cd00051, EFh, 1 hit
cd11808, SH3_Alpha_Spectrin, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR035825, Alpha_Spectrin_SH3
IPR011992, EF-hand-dom_pair
IPR014837, EF-hand_Ca_insen
IPR018247, EF_Hand_1_Ca_BS
IPR002048, EF_hand_dom
IPR036028, SH3-like_dom_sf
IPR001452, SH3_domain
IPR018159, Spectrin/alpha-actinin
IPR002017, Spectrin_repeat

Pfam protein domain database

More...Pfami		View protein in Pfam
PF13499, EF-hand_7, 1 hit
PF08726, EFhand_Ca_insen, 1 hit
PF00018, SH3_1, 1 hit
PF00435, Spectrin, 20 hits

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00452, SH3DOMAIN

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00054, EFh, 2 hits
SM00326, SH3, 1 hit
SM00150, SPEC, 20 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF47473, SSF47473, 1 hit
SSF50044, SSF50044, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00018, EF_HAND_1, 2 hits
PS50222, EF_HAND_2, 2 hits
PS50002, SH3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

E9Q447-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDPSGVKVLE TAEDIQERRQ QVLDRYHRFK ELSTLRRQKL EDSYRFQFFQ 
        60         70         80         90        100
RDAEELEKWI QEKLQVASDE NYKDPTNLQG KLQKHQAFEA EVQANSGAIV 
       110        120        130        140        150
KLDETGNLMI SEGHFASETI RTRLMELHRQ WELLLEKMRE KGIKLLQAQK 
       160        170        180        190        200
LVQYLRECED VMDWINDKEA IVTSEELGQD LEHVEVLQKK FEEFQTDLAA 
       210        220        230        240        250
HEERVNEVSQ FAAKLIQEQH PEEELIKTKQ DEVNAAWQRL KGLALQRQGK 
       260        270        280        290        300
LFGAAEVQRF NRDVDETIGW IKEKEQLMAS DDFGRDLASV QALLRKHEGL 
       310        320        330        340        350
ERDLAALEDK VKALCAEADR LQQSHPLSAS QIQVKREELI TNWEQIRTLA 
       360        370        380        390        400
AERHARLDDS YRLQRFLADF RDLTSWVTEM KALINADELA NDVAGAEALL 
       410        420        430        440        450
DRHQEHKGEI DAHEDSFKSA DESGQALLAA SHYASDEVRE KLSILSEERT 
       460        470        480        490        500
ALLELWELRR QQYEQCMDLQ LFYRDTEQVD NWMSKQEAFL LNEDLGDSLD 
       510        520        530        540        550
SVEALLKKHE DFEKSLSAQE EKITALDEFA TKLIQNNHYA MEDVATRRDA 
       560        570        580        590        600
LLSRRNALHE RAMHRRAQLA DSFHLQQFFR DSDELKSWVN EKMKTATDEA 
       610        620        630        640        650
YKDPSNLQGK VQKHQAFEAE LSANQSRIDA LEKAGQKLID VNHYAKEEVA 
       660        670        680        690        700
ARMNEVISLW KKLLEATELK GIKLREANQQ QQFNRNVEDI ELWLYEVEGH 
       710        720        730        740        750
LASDDYGKDL TNVQNLQKKH ALLEADVAAH QDRIDGITIQ ARQFQDAGHF 
       760        770        780        790        800
DAENIKKKQE ALVARYEALK EPMVARKQKL ADSLRLQQLF RDVEDEETWI 
       810        820        830        840        850
REKEPIAAST NRGKDLIGVQ NLLKKHQALQ AEIAGHEPRI KAVTQKGNAM 
       860        870        880        890        900
VEEGHFAAED VKAKLSELNQ KWEALKAKAS QRRQDLEDSL QAQQYFADAN 
       910        920        930        940        950
EAESWMREKE PIVGSTDYGK DEDSAEALLK KHEALMSDLS AYGSSIQALR 
       960        970        980        990       1000
EQAQSCRQQV APMDDETGKE LVLALYDYQE KSPREVTMKK GDILTLLNST 
      1010       1020       1030       1040       1050
NKDWWKVEVN DRQGFVPAAY VKKLDPAQSA SRENLLEEQG SIALRQGQID 
      1060       1070       1080       1090       1100
NQYQSLLELG EKRKGMLEKS CKKFMLFREA NELQQWITEK EAALTNEEVG 
      1110       1120       1130       1140       1150
ADLEQVEVLQ KKFDDFQKDL KANESRLKDI NKVAEDLESE GLMAEEVQAV 
      1160       1170       1180       1190       1200
QQQEVYGAMP RDEADSKTAS PWKSARLMVH TVATFNSIKE LNERWRSLQQ 
      1210       1220       1230       1240       1250
LAEERSQLLG SAHEVQRFHR DADETKEWIE EKNQALNTDN YGHDLASVQA 
      1260       1270       1280       1290       1300
LQRKHEGFER DLAALGDKVN SLGETAQRLI QSHPESAEDL KEKCTELNQA 
      1310       1320       1330       1340       1350
WTSLGKRADQ RKAKLGDSHD LQRFLSDFRD LMSWINGIRG LVSSDELAKD 
      1360       1370       1380       1390       1400
VTGAEALLER HQEHRTEIDA RAGTFQAFEQ FGQQLLAHGH YASPEIKEKL 
      1410       1420       1430       1440       1450
DILDQERTDL EKAWVQRRMM LDHCLELQLF HRDCEQAENW MAAREAFLNT 
      1460       1470       1480       1490       1500
EDKGDSLDSV EALIKKHEDF DKAINVQEEK IAALQAFADQ LIAVDHYAKG 
      1510       1520       1530       1540       1550
DIANRRNEVL DRWRRLKAQM IEKRSKLGES QTLQQFSRDV DEIEAWISEK 
      1560       1570       1580       1590       1600
LQTASDESYK DPTNIQLSKL LSKHQKHQAF EAELHANADR IRGVIDMGNS 
      1610       1620       1630       1640       1650
LIERGACAGS EDAVKARLAA LADQWQFLVQ KSAEKSQKLK EANKQQNFNT 
      1660       1670       1680       1690       1700
GIKDFDFWLS EVEALLASED YGKDLASVNN LLKKHQLLEA DISAHEDRLK 
      1710       1720       1730       1740       1750
DLNSQADSLM TSSAFDTSQV KEKRDTINGR FQKIKSMATS RRAKLSESHR 
      1760       1770       1780       1790       1800
LHQFFRDMDD EESWIKEKKL LVSSEDYGRD LTGVQNLRKK HKRLEAELAA 
      1810       1820       1830       1840       1850
HEPAIQGVLD TGKKLSDDNT IGQEEIQQRL AQFVEHWKEL KQLAAARGQR 
      1860       1870       1880       1890       1900
LEESLEYQQF VANVEEEEAW INEKMTLVAS EDYGDTLAAI QGLLKKHEAF 
      1910       1920       1930       1940       1950
ETDFTVHKDR VNDVCTNGQD LIKKNNHHEE NISSKMKGLN GKVSDLEKAA 
      1960       1970       1980       1990       2000
AQRKAKLDEN SAFLQFNWKA DVVESWIGEK ENSLKTDDYG RDLSSVQTLL 
      2010       2020       2030       2040       2050
TKQETFDAGL QAFQQEGIAN ITALKDQLLA AKHIQSKAIE ARHASLMKRW 
      2060       2070       2080       2090       2100
TQLLANSATR KKKLLEAQSH FRKVEDLFLT FAKKASAFNS WFENAEEDLT 
      2110       2120       2130       2140       2150
DPVRCNSLEE IKALREAHDA FRSSLSSAQA DFNQLAELDR QIKSFRVASN 
      2160       2170       2180       2190       2200
PYTWFTMEAL EETWRNLQKI IKERELELQK EQRRQEENDK LRQEFAQHAN 
      2210       2220       2230       2240       2250
AFHQWIQETR TYLLDGIAYR RVIRVCQYEV GDDLSGRSCM VEESGTLESQ 
      2260       2270       2280       2290       2300
LEATKRKHQE IRAMRSQLKK IEDLGAAMEE ALILDNKYTE HSTVGLAQQW 
      2310       2320       2330       2340       2350
DQLDQLGMRM QHNLEQQIQA RNTTGVTEEA LKEFSMMFKH FDKDKSGRLN 
      2360       2370       2380       2390       2400
HQEFKSCLRS LGYDLPMVEE GEPDPEFEAI LDTVDPNRDG HVSLQEYMAF 
      2410       2420       2430       2440       2450
MISRETENVK SSEEIESAFR ALSSEGKPYV TKEELYQNLT REQADYCVSH 
      2460       2470 
MKPYVDGKGR ELPTAFDYVE FTRSLFVN
Length:2,478
Mass (Da):285,345
Last modified:April 5, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iFB9ED04A506CCF22
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P16546SPTN1_MOUSE
Spectrin alpha chain, non-erythrocy...
Sptan1 Spna2, Spta2
2,472Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A3KGU9A3KGU9_MOUSE
Spectrin alpha chain, non-erythrocy...
Sptan1 Spna2
2,498Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A3KGU7A3KGU7_MOUSE
Spectrin alpha chain, non-erythrocy...
Sptan1 Spna2
2,477Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A3KGU5A3KGU5_MOUSE
Spectrin alpha chain, non-erythrocy...
Sptan1 Spna2
2,457Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A3KGU4A3KGU4_MOUSE
Spectrin alpha chain, non-erythrocy...
Sptan1 Spna2
219Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A5F8MQC3A0A5F8MQC3_MOUSE
Spectrin alpha chain, non-erythrocy...
Sptan1
112Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSMUST00000113719; ENSMUSP00000109348; ENSMUSG00000057738

UCSC genome browser

More...UCSCi		uc008jar.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

SMRiE9Q447
ModBaseiSearch...

PTM databases

iPTMnetiE9Q447

Proteomic databases

jPOSTiE9Q447
MaxQBiE9Q447
PeptideAtlasiE9Q447
ProteomicsDBi314666

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		1910, 467 antibodies from 44 providers

Genome annotation databases

EnsembliENSMUST00000113719; ENSMUSP00000109348; ENSMUSG00000057738
UCSCiuc008jar.1, mouse

Organism-specific databases

MGIiMGI:98386, Sptan1
VEuPathDBiHostDB:ENSMUSG00000057738

Phylogenomic databases

GeneTreeiENSGT00940000156662
PhylomeDBiE9Q447

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		Sptan1, mouse

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSMUSG00000057738, Expressed in facial nucleus and 328 other tissues
ExpressionAtlasiE9Q447, baseline and differential
GenevisibleiE9Q447, MM

Family and domain databases

CDDicd00051, EFh, 1 hit
cd11808, SH3_Alpha_Spectrin, 1 hit
InterProiView protein in InterPro
IPR035825, Alpha_Spectrin_SH3
IPR011992, EF-hand-dom_pair
IPR014837, EF-hand_Ca_insen
IPR018247, EF_Hand_1_Ca_BS
IPR002048, EF_hand_dom
IPR036028, SH3-like_dom_sf
IPR001452, SH3_domain
IPR018159, Spectrin/alpha-actinin
IPR002017, Spectrin_repeat
PfamiView protein in Pfam
PF13499, EF-hand_7, 1 hit
PF08726, EFhand_Ca_insen, 1 hit
PF00018, SH3_1, 1 hit
PF00435, Spectrin, 20 hits
PRINTSiPR00452, SH3DOMAIN
SMARTiView protein in SMART
SM00054, EFh, 2 hits
SM00326, SH3, 1 hit
SM00150, SPEC, 20 hits
SUPFAMiSSF47473, SSF47473, 1 hit
SSF50044, SSF50044, 1 hit
PROSITEiView protein in PROSITE
PS00018, EF_HAND_1, 2 hits
PS50222, EF_HAND_2, 2 hits
PS50002, SH3, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiE9Q447_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E9Q447
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: January 19, 2022
This is version 84 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again