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Protein

Olfactory receptor

Gene

Olfr749

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer
Biological processOlfactionUniRule annotationSAAS annotation, Sensory transduction

Enzyme and pathway databases

ReactomeiR-MMU-381753 Olfactory Signaling Pathway

Names & Taxonomyi

Protein namesi
Recommended name:
Olfactory receptorUniRule annotation
Gene namesi
Name:Olfr749Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 14

Organism-specific databases

MGIiMGI:3030583 Olfr749

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei24 – 47HelicalUniRule annotationAdd BLAST24
Transmembranei59 – 80HelicalUniRule annotationAdd BLAST22
Transmembranei100 – 119HelicalUniRule annotationAdd BLAST20
Transmembranei139 – 157HelicalUniRule annotationAdd BLAST19
Transmembranei204 – 225HelicalUniRule annotationAdd BLAST22
Transmembranei237 – 260HelicalUniRule annotationAdd BLAST24
Transmembranei272 – 291HelicalUniRule annotationAdd BLAST20

Keywords - Cellular componenti

Cell membraneUniRule annotationSAAS annotation, Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000059069 Expressed in 2 organ(s), highest expression level in thymus
GenevisibleiE9Q438 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000074242

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini40 – 289G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST250

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG410IFEZ Eukaryota
ENOG411183S LUCA
GeneTreeiENSGT00890000139362
InParanoidiE9Q438
KOiK04257
OMAiLGFPGCW
OrthoDBiEOG091G0AZH
PhylomeDBiE9Q438
TreeFamiTF338968

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR000725 Olfact_rcpt
PfamiView protein in Pfam
PF13853 7tm_4, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PR00245 OLFACTORYR
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequencei

Sequence statusi: Complete.

E9Q438-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNRSAAHVTE FVLLGFPGSW KIQIFLFVLF LVFYVLTLLG NGAIICAVRC
60 70 80 90 100
DSRLHTPMYF LLGNFAFLEI WYVSSTIPNI LANILSKTKA ISFSGCFLQF
110 120 130 140 150
YFFFSLGTTE CLFLAVMAYD RYLAICRPLH YPTIMTRRLC CILVSSCWLI
160 170 180 190 200
GFLGYPIPIF SISQLPFCGS NIIDHFLCDM DPLMALSCAP APITEFIFYA
210 220 230 240 250
QSSFVLFFTI AYILRSYILL LRAVFQVPSA AGRRKAFSTC GSHLVVVSLF
260 270 280 290 300
YGTVMVMYVS PTYGIPILMQ KILTLVYSVM TPLFNPLIYS LRNKDMKLAL
310
RNVLLGMRIV KNM
Length:313
Mass (Da):35,481
Last modified:April 5, 2011 - v1
Checksum:iE485426FE9D0783F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC140280 Genomic DNA No translation available.
RefSeqiNP_064684.2, NM_020288.2
UniGeneiMm.103732

Genome annotation databases

EnsembliENSMUST00000074674; ENSMUSP00000074242; ENSMUSG00000059069
ENSMUST00000214290; ENSMUSP00000150627; ENSMUSG00000059069
GeneIDi56858
KEGGimmu:56858
UCSCiuc011zjv.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC140280 Genomic DNA No translation available.
RefSeqiNP_064684.2, NM_020288.2
UniGeneiMm.103732

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000074242

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

DNASUi56858
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000074674; ENSMUSP00000074242; ENSMUSG00000059069
ENSMUST00000214290; ENSMUSP00000150627; ENSMUSG00000059069
GeneIDi56858
KEGGimmu:56858
UCSCiuc011zjv.1 mouse

Organism-specific databases

CTDi56858
MGIiMGI:3030583 Olfr749

Phylogenomic databases

eggNOGiENOG410IFEZ Eukaryota
ENOG411183S LUCA
GeneTreeiENSGT00890000139362
InParanoidiE9Q438
KOiK04257
OMAiLGFPGCW
OrthoDBiEOG091G0AZH
PhylomeDBiE9Q438
TreeFamiTF338968

Enzyme and pathway databases

ReactomeiR-MMU-381753 Olfactory Signaling Pathway

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000059069 Expressed in 2 organ(s), highest expression level in thymus
GenevisibleiE9Q438 MM

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR000725 Olfact_rcpt
PfamiView protein in Pfam
PF13853 7tm_4, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PR00245 OLFACTORYR
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE9Q438_MOUSE
AccessioniPrimary (citable) accession number: E9Q438
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: November 7, 2018
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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