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Protein
Submitted name:

Complement receptor type 2

Gene

Cr2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Enzyme and pathway databases

ReactomeiR-MMU-977606 Regulation of Complement cascade

Names & Taxonomyi

Protein namesi
Submitted name:
Complement receptor type 2Imported
Gene namesi
Name:Cr2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 1

Organism-specific databases

MGIiMGI:88489 Cr2

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi2 ↔ 45PROSITE-ProRule annotation
Disulfide bondi225 ↔ 252PROSITE-ProRule annotation
Disulfide bondi284 ↔ 311PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Proteomic databases

PaxDbiE9Q3S5
PRIDEiE9Q3S5

Expressioni

Gene expression databases

BgeeiENSMUSG00000026616 Expressed in 71 organ(s), highest expression level in spleen
ExpressionAtlasiE9Q3S5 baseline and differential

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000044261

Structurei

3D structure databases

ProteinModelPortaliE9Q3S5
SMRiE9Q3S5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 60SushiInterPro annotationAdd BLAST60
Domaini61 – 122SushiInterPro annotationAdd BLAST62
Domaini123 – 193SushiInterPro annotationAdd BLAST71
Domaini195 – 254SushiInterPro annotationAdd BLAST60
Domaini255 – 313SushiInterPro annotationAdd BLAST59

Keywords - Domaini

SushiPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG4297 Eukaryota
ENOG410XPJ1 LUCA
GeneTreeiENSGT00760000118803
TreeFamiTF334137

Family and domain databases

CDDicd00033 CCP, 5 hits
InterProiView protein in InterPro
IPR035976 Sushi/SCR/CCP_sf
IPR000436 Sushi_SCR_CCP_dom
PfamiView protein in Pfam
PF00084 Sushi, 5 hits
SMARTiView protein in SMART
SM00032 CCP, 5 hits
SUPFAMiSSF57535 SSF57535, 5 hits
PROSITEiView protein in PROSITE
PS50923 SUSHI, 5 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All

E9Q3S5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
QCKLLPKYSF AKPSIVSDKS EFAIGTTWEY KCRPGYFRKS FIITCLETSK
60 70 80 90 100
WSDAQQFCKR KPCMNPQEPL HGSVHINTGI EFGSTITYSC NQGYRLIGDS
110 120 130 140 150
SATCIVSDNT VMWDNDMPLC ESIPCESPPA ISNGDFYSSS RDSFFYGMVV
160 170 180 190 200
TYYCHTGKNR EKLFDLVGEK SIYCTSKDNQ VGIWNSPPPQ CIPRVKCPMP
210 220 230 240 250
EIENGLVESG FKHSFFLNDT VIFKCKSGFT MKGSRIAWCQ PNSKWSPPLP
260 270 280 290 300
TCFMGCLPPQ NILHGDYNKK DEFFSVGQKV SYSCNPGYTL IGTNLVECTS
310 320 330 340
LGTWSNTVPT CEVKSCDAIP NHLLHGRVFL PPNLQLGAEV SFVCDLG
Length:347
Mass (Da):38,768
Last modified:October 3, 2012 - v2
Checksum:i717F9FF74A63A86F
GO

Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P19070CR2_MOUSE
Complement receptor type 2
Cr2
1,025Annotation score:
Q9DC83Q9DC83_MOUSE
Complement receptor 2
Cr2
1,032Annotation score:
A0A1B0GS59A0A1B0GS59_MOUSE
Complement receptor type 2
Cr2
1,408Annotation score:
A0A0A6YWU7A0A0A6YWU7_MOUSE
Complement receptor type 2
Cr2
735Annotation score:
A0A0A6YWG3A0A0A6YWG3_MOUSE
Complement receptor type 2
Cr2
1,026Annotation score:
Q32M14Q32M14_MOUSE
Complement receptor type 2
Cr2
50Annotation score:
A0A0A6YXU7A0A0A6YXU7_MOUSE
Complement receptor type 2
Cr2
62Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC139206 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSMUST00000043104; ENSMUSP00000044261; ENSMUSG00000026616

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC139206 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliE9Q3S5
SMRiE9Q3S5
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000044261

Proteomic databases

PaxDbiE9Q3S5
PRIDEiE9Q3S5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000043104; ENSMUSP00000044261; ENSMUSG00000026616

Organism-specific databases

MGIiMGI:88489 Cr2

Phylogenomic databases

eggNOGiKOG4297 Eukaryota
ENOG410XPJ1 LUCA
GeneTreeiENSGT00760000118803
TreeFamiTF334137

Enzyme and pathway databases

ReactomeiR-MMU-977606 Regulation of Complement cascade

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000026616 Expressed in 71 organ(s), highest expression level in spleen
ExpressionAtlasiE9Q3S5 baseline and differential

Family and domain databases

CDDicd00033 CCP, 5 hits
InterProiView protein in InterPro
IPR035976 Sushi/SCR/CCP_sf
IPR000436 Sushi_SCR_CCP_dom
PfamiView protein in Pfam
PF00084 Sushi, 5 hits
SMARTiView protein in SMART
SM00032 CCP, 5 hits
SUPFAMiSSF57535 SSF57535, 5 hits
PROSITEiView protein in PROSITE
PS50923 SUSHI, 5 hits
ProtoNetiSearch...

Entry informationi

Entry nameiE9Q3S5_MOUSE
AccessioniPrimary (citable) accession number: E9Q3S5
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: October 3, 2012
Last modified: September 12, 2018
This is version 58 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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