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Protein
Submitted name:

Nucleoporin 153

Gene

Nup153

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-MMU-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript
R-MMU-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein
R-MMU-191859 snRNP Assembly
R-MMU-3108214 SUMOylation of DNA damage response and repair proteins
R-MMU-3232142 SUMOylation of ubiquitinylation proteins
R-MMU-3301854 Nuclear Pore Complex (NPC) Disassembly
R-MMU-3371453 Regulation of HSF1-mediated heat shock response
R-MMU-4085377 SUMOylation of SUMOylation proteins
R-MMU-4551638 SUMOylation of chromatin organization proteins
R-MMU-4570464 SUMOylation of RNA binding proteins
R-MMU-4615885 SUMOylation of DNA replication proteins
R-MMU-5578749 Transcriptional regulation by small RNAs

Names & Taxonomyi

Protein namesi
Submitted name:
Nucleoporin 153Imported
Gene namesi
Name:Nup153Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 13

Organism-specific databases

MGIiMGI:2385621 Nup153

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

MaxQBiE9Q3G8
PaxDbiE9Q3G8
PeptideAtlasiE9Q3G8
PRIDEiE9Q3G8

Expressioni

Gene expression databases

BgeeiENSMUSG00000021374 Expressed in 270 organ(s), highest expression level in embryonic stem cell
ExpressionAtlasiE9Q3G8 baseline and differential
GenevisibleiE9Q3G8 MM

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

IntActiE9Q3G8, 1 interactor
STRINGi10090.ENSMUSP00000021803

Structurei

3D structure databases

ProteinModelPortaliE9Q3G8
SMRiE9Q3G8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini653 – 683RanBP2-typeInterPro annotationAdd BLAST31
Domaini717 – 746RanBP2-typeInterPro annotationAdd BLAST30
Domaini785 – 814RanBP2-typeInterPro annotationAdd BLAST30
Domaini842 – 871RanBP2-typeInterPro annotationAdd BLAST30

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG4719 Eukaryota
ENOG41107SV LUCA
GeneTreeiENSGT00700000104544
InParanoidiE9Q3G8
KOiK14296
OMAiNGKNMFS
OrthoDBiEOG091G015X
TreeFamiTF323517

Family and domain databases

InterProiView protein in InterPro
IPR026054 Nucleoporin
IPR037625 NUP153
IPR013913 Nup153_N
IPR018892 Retro-transposon_transp_CS
IPR001876 Znf_RanBP2
IPR036443 Znf_RanBP2_sf
PANTHERiPTHR23193 PTHR23193, 1 hit
PTHR23193:SF31 PTHR23193:SF31, 1 hit
PfamiView protein in Pfam
PF08604 Nup153, 1 hit
PF10599 Nup_retrotrp_bd, 1 hit
PF00641 zf-RanBP, 4 hits
SMARTiView protein in SMART
SM00547 ZnF_RBZ, 4 hits
SUPFAMiSSF90209 SSF90209, 3 hits
PROSITEiView protein in PROSITE
PS01358 ZF_RANBP2_1, 4 hits
PS50199 ZF_RANBP2_2, 4 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

E9Q3G8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASEAGGIGG GGGGGKIRTR RCHQGPVKPY QQGRPQHQGI LSRVTESVKN
60 70 80 90 100
IVPGWLQRYF NKSENACSCS PDADEVPPWP ENREDEHAIY ADENTNTDDG
110 120 130 140 150
RITPDPAGSN TEEPSTTSTA SNYPDVLTRP SLHRSHLNFS VLESPALHCQ
160 170 180 190 200
PSTSSAFPIG SSGFSLVKEI KDSTSQHDDD NISTTSGFSS RASEKDIAVS
210 220 230 240 250
KNTSLPPLWS PEAERSHSLS QHTAISSKKP AFNLSAFGTL STSLGNSSIL
260 270 280 290 300
KTSQLGDSPF YPGKTTYGGA AAAVRQNKVR STPYQAPVRR QMKAKQLNAQ
310 320 330 340 350
SYGVTSSTAR RILQSLEKMS SPLADAKRIP SAVSSPLNSP LDRSGIDNTV
360 370 380 390 400
FQAKKEKVDS QYPPVQRLMT PKPVSIATNR TVYFKPSLTP SGDLRKTNQR
410 420 430 440 450
IDKKNSTVDE KSISRQNREQ ESGFSYPNFS IPAANGLSSG VGGGGGKMRR
460 470 480 490 500
ERTHFVAPKP PENEEVEAPL LPQISLPISS SSLPTFSFSS PVTSASPSPV
510 520 530 540 550
SSSQPLPNKV QMTSLGSTGS PVFTFSSPIV KSTQAAVLPP ASIGFTFSVP
560 570 580 590 600
LAKTEFSGSN SSSETVLSSS AQDITAVNSS SYKKRSAPCE DPFTPAKILR
610 620 630 640 650
EGSVLDILKT PGFASPKVDS PALQPTTTSS IVYTRPAIST FSSSGIEYGE
660 670 680 690 700
SLKAGSSWQC DTCLLQNKVT DNKCIACQAA KLPLKETAKQ TGTGTPSKSD
710 720 730 740 750
KPASTSGTGF GDKFKPAIGT WDCDTCLVQN KPEAVKCVAC ETPKPGTGVK
760 770 780 790 800
RALTLTVASE SPVTASSSTT VTTGTLGFGD KFKRPVGSWE CPVCCVCNKA
810 820 830 840 850
EDNRCVSCTS EKPGLVSASS SSPAPVSLSS GGCLGLDKFK KPEGSWDCEV
860 870 880 890 900
CLVQNKADSA KCIACESAKP GTKSEFKGFG TSSSLNPAPS AFKFGIPSSS
910 920 930 940 950
SGLSQTLTST GNFKFGDQGG FKLGTSSDSG STNTMNTNFK FSKPTGDFKF
960 970 980 990 1000
GVLSDSKPEE VKNDNKNDNF QFGSSSGLTN PASSAPFQFG VSTLGQQEKK
1010 1020 1030 1040 1050
EELPKSSPAG FSFGAGVNNP PNAAIDTTAT SENKSGFNFG TLDTKSVSVT
1060 1070 1080 1090 1100
PFTYKTTEAK KEDAPATKGG FTFGKVGSSS LPSSSMFVLG RTEEKQQEPV
1110 1120 1130 1140 1150
TSTSLVFGKK ADSEEPKCQP VFSFGNSEQT KDESSKPTFS FSVAKPSGKE
1160 1170 1180 1190 1200
SEQLAKATFA FGNQTNTTTD QGAAKPVFSF LNSSSSSSSA PATSSSGGIF
1210 1220 1230 1240 1250
GSSTSSSNPP VAAFVFGQAS NPVSSSAFGN AAESSTSQSL LFPQESEPAT
1260 1270 1280 1290 1300
TSSTAPAASP FVFGTGASSN SVSSGFTFGA TTTSSSSGSS FVFGTGHSAP
1310 1320 1330 1340 1350
SASPAFGANQ TPTFGQSQGA SQPNPPSFGS ISSSTALFSA GSQPVPPPIF
1360 1370 1380 1390 1400
GTVSSSSQPP VFGQQPSQSA FGSGTANASS VFQFGSSTTN FNFTNNNPSG
1410 1420 1430 1440 1450
VFTFGASPST PAASAQPSGS GVFSFSQSPA SFTVGSNGKN MFSSSGTSVS
1460
GRKIKTAVRR KK
Length:1,462
Mass (Da):152,008
Last modified:April 5, 2011 - v1
Checksum:i1A6FC0CD8AA2C3FC
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A286YE24A0A286YE24_MOUSE
Nucleoporin 153
Nup153
303Annotation score:
A0A286YCY7A0A286YCY7_MOUSE
Nucleoporin 153
Nup153
203Annotation score:
A0A286YCP2A0A286YCP2_MOUSE
Nucleoporin 153
Nup153
256Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124598 Genomic DNA No translation available.
RefSeqiNP_786925.2, NM_175749.2
UniGeneiMm.255398
Mm.445069

Genome annotation databases

EnsembliENSMUST00000021803; ENSMUSP00000021803; ENSMUSG00000021374
GeneIDi218210
KEGGimmu:218210
UCSCiuc007qhj.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124598 Genomic DNA No translation available.
RefSeqiNP_786925.2, NM_175749.2
UniGeneiMm.255398
Mm.445069

3D structure databases

ProteinModelPortaliE9Q3G8
SMRiE9Q3G8
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiE9Q3G8, 1 interactor
STRINGi10090.ENSMUSP00000021803

Proteomic databases

MaxQBiE9Q3G8
PaxDbiE9Q3G8
PeptideAtlasiE9Q3G8
PRIDEiE9Q3G8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000021803; ENSMUSP00000021803; ENSMUSG00000021374
GeneIDi218210
KEGGimmu:218210
UCSCiuc007qhj.2 mouse

Organism-specific databases

CTDi9972
MGIiMGI:2385621 Nup153

Phylogenomic databases

eggNOGiKOG4719 Eukaryota
ENOG41107SV LUCA
GeneTreeiENSGT00700000104544
InParanoidiE9Q3G8
KOiK14296
OMAiNGKNMFS
OrthoDBiEOG091G015X
TreeFamiTF323517

Enzyme and pathway databases

ReactomeiR-MMU-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript
R-MMU-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein
R-MMU-191859 snRNP Assembly
R-MMU-3108214 SUMOylation of DNA damage response and repair proteins
R-MMU-3232142 SUMOylation of ubiquitinylation proteins
R-MMU-3301854 Nuclear Pore Complex (NPC) Disassembly
R-MMU-3371453 Regulation of HSF1-mediated heat shock response
R-MMU-4085377 SUMOylation of SUMOylation proteins
R-MMU-4551638 SUMOylation of chromatin organization proteins
R-MMU-4570464 SUMOylation of RNA binding proteins
R-MMU-4615885 SUMOylation of DNA replication proteins
R-MMU-5578749 Transcriptional regulation by small RNAs

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000021374 Expressed in 270 organ(s), highest expression level in embryonic stem cell
ExpressionAtlasiE9Q3G8 baseline and differential
GenevisibleiE9Q3G8 MM

Family and domain databases

InterProiView protein in InterPro
IPR026054 Nucleoporin
IPR037625 NUP153
IPR013913 Nup153_N
IPR018892 Retro-transposon_transp_CS
IPR001876 Znf_RanBP2
IPR036443 Znf_RanBP2_sf
PANTHERiPTHR23193 PTHR23193, 1 hit
PTHR23193:SF31 PTHR23193:SF31, 1 hit
PfamiView protein in Pfam
PF08604 Nup153, 1 hit
PF10599 Nup_retrotrp_bd, 1 hit
PF00641 zf-RanBP, 4 hits
SMARTiView protein in SMART
SM00547 ZnF_RBZ, 4 hits
SUPFAMiSSF90209 SSF90209, 3 hits
PROSITEiView protein in PROSITE
PS01358 ZF_RANBP2_1, 4 hits
PS50199 ZF_RANBP2_2, 4 hits
ProtoNetiSearch...

Entry informationi

Entry nameiE9Q3G8_MOUSE
AccessioniPrimary (citable) accession number: E9Q3G8
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: November 7, 2018
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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