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Protein
Submitted name:

TAR RNA-binding protein 1

Gene

Tarbp1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • RNA binding Source: InterPro
  • tRNA (guanine) methyltransferase activity Source: GO_Central

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
TAR RNA-binding protein 1Imported
Gene namesi
Name:Tarbp1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 8

Organism-specific databases

MGIiMGI:4936930 Tarbp1

PTM / Processingi

Proteomic databases

MaxQBiE9Q368
PaxDbiE9Q368
PeptideAtlasiE9Q368
PRIDEiE9Q368

Expressioni

Gene expression databases

BgeeiENSMUSG00000090290 Expressed in 22 organ(s), highest expression level in thymus

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000129815

Structurei

3D structure databases

ProteinModelPortaliE9Q368
SMRiE9Q368
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1422 – 1563SpoU_methylaseInterPro annotationAdd BLAST142

Phylogenomic databases

eggNOGiKOG0839 Eukaryota
COG0566 LUCA
GeneTreeiENSGT00390000003939
InParanoidiE9Q368
KOiK15333
OMAiWFEAKLV
OrthoDBiEOG091G0UYQ
PhylomeDBiE9Q368
TreeFamiTF314976

Family and domain databases

Gene3Di3.40.1280.10, 1 hit
InterProiView protein in InterPro
IPR029028 Alpha/beta_knot_MTases
IPR016024 ARM-type_fold
IPR025806 Prob_MeTrfase_TARBP1
IPR001537 SpoU_MeTrfase
IPR029026 tRNA_m1G_MTases_N
PfamiView protein in Pfam
PF00588 SpoU_methylase, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit
SSF75217 SSF75217, 1 hit
PROSITEiView protein in PROSITE
PS51624 SAM_MT_TRMH_2, 1 hit

Sequencei

Sequence statusi: Complete.

E9Q368-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MERVLADALL TQSREPGELL GALCGGEASA ERAETLRLVL QRLEERGAGA
60 70 80 90 100
GALAKAAHEV ARDHLVPLLH ASQGGGPARP RVLRAASAAL RSCARLAGPE
110 120 130 140 150
LAVTLAEEAL RELPSAPAVE LLAAVAPCLR APEDAPLLRR LGRASVELAL
160 170 180 190 200
AGDAPPAVGA RLLPALAQSA EPALRAAWDA LSSAGPGAEG STGPELLVLS
210 220 230 240 250
ALAEKLLTNH ERHGDLDARL CGRFWRTVQA GLGRAQDGLT RKRARYLLQR
260 270 280 290 300
AVQVSAELAV DCSCSPQDTK GPSLFWWSEK RKDELLKFWE NYILIMEILE
310 320 330 340 350
GNQIHVIKPA LPKLNRLFEC AVSEENGCWL FHPSWHTCIY KRMFESENKI
360 370 380 390 400
LAKEGVIHFL ELYDVKSLPY SPELSEFITG PLMDALSESC LYSRSPGQPL
410 420 430 440 450
GSDSPLGLKL QKFLVTYTSL LPEETKSCFL LKLIQRMADR HWCAVPVLFL
460 470 480 490 500
SRALASIPSC KALGGEGLLA LRDVLQRTMI THQVLLRGAA QCYLLQTAMR
510 520 530 540 550
LVDVEKVSLS DISAFLLSLR QEESLGRGTV LWTELCDWLR VNERYFKQSS
560 570 580 590 600
LGGSDGQEAS LNAYVKNLVQ EFVKSPGWEK ESSFMPDWLD ARLTALMVLL
610 620 630 640 650
AVDVEGLKTK FREKQRTQNV LRIFLDPLLD ALGKLGTNAY MPLLRTDRCL
660 670 680 690 700
QLLVRLLHSC VPRRPGAQDD EVSTALQGSI MSASESVSQF VLRRLTMNEL
710 720 730 740 750
QDVADLDRCQ LYLTVLSELM SLQVKLGWKA GNPISRVLSP LKNACVRHLQ
760 770 780 790 800
EAEDRQEPTL SHQVQRVVSM AALAALCEAV DQYPVLQPDS PNAEPVDRFL
810 820 830 840 850
SALPLNHVLQ KPRSEEQSIG VCPLENGSVF EESLSSKGWG KVVAQYLHDQ
860 870 880 890 900
WVCLSFLLRK HHHLIPSTES DVLEGFLPTA ETPVQALQAA LDVLTVLPAG
910 920 930 940 950
RILPVFRCME VLVPKLLTSE ETLCIESFDV AWKIISSLSN TQLTFWPNLK
960 970 980 990 1000
AFVHFVFDHE ILTIAAKLKG QVYFKIKEIM CKMIEMSSIK SGVFNILIRH
1010 1020 1030 1040 1050
CCQSWLVAAS GVSQGSFSSA KDYSELVLEA CVFGTVFRRD QRLIQDVQTF
1060 1070 1080 1090 1100
IENLGQGCAA NVIIENAKRE DYYVRICAIK FLCLLDGSDV SHKLFLEALA
1110 1120 1130 1140 1150
IKLLDKDESA SRSRTRYHEN SLQHRVKNRV WQTLLVLFPA FDQNFLHGII
1160 1170 1180 1190 1200
DKVFHAGFTN NQASIKYFIE WLIILILHKF PEFLPKFWAC FSYGEEKIKA
1210 1220 1230 1240 1250
SICTFLSVLS HLDIIVQNIP EKKLVLKQAL TVALQWCLSH NFSVRLYALV
1260 1270 1280 1290 1300
ALKKAWHLCK TLQFEECGAW TAVIECSLSQ AESMHGAGNA RKNWQRIQDH
1310 1320 1330 1340 1350
FFFSTFHPLK DYCLETIFYT LPRLSGVTGE EWIALDKFAN FTDIPSNAGS
1360 1370 1380 1390 1400
QWYLSGTALG ELSPGDWSQQ DQGSTLGEAD SQSEWADVQK KIIPWGQSAL
1410 1420 1430 1440 1450
ESDLELEFQD RAAKLGKSIS RLIVVASLID KPTNLGGLCR TCEVFGAAVL
1460 1470 1480 1490 1500
VVGSLQCVSD RQFQHLSVSA EQWLPLVEVR PSQLMNYLQQ KKAEGYTVIG
1510 1520 1530 1540 1550
VEQTAQSSDL AQYRFPEKSL LLLGNEREGI PANLIQQLDV CVEIPQQGII
1560 1570
RSLNVHVSGA LLIWEYTRQQ LLGCAEPPS
Length:1,579
Mass (Da):175,691
Last modified:April 5, 2011 - v1
Checksum:i3950E152817C2954
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC151908 Genomic DNA No translation available.
RefSeqiNP_001153379.1, NM_001159907.1
UniGeneiMm.482479

Genome annotation databases

EnsembliENSMUST00000170518; ENSMUSP00000129815; ENSMUSG00000090290
GeneIDi212728
KEGGimmu:212728
UCSCiuc012gne.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC151908 Genomic DNA No translation available.
RefSeqiNP_001153379.1, NM_001159907.1
UniGeneiMm.482479

3D structure databases

ProteinModelPortaliE9Q368
SMRiE9Q368
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000129815

Proteomic databases

MaxQBiE9Q368
PaxDbiE9Q368
PeptideAtlasiE9Q368
PRIDEiE9Q368

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000170518; ENSMUSP00000129815; ENSMUSG00000090290
GeneIDi212728
KEGGimmu:212728
UCSCiuc012gne.1 mouse

Organism-specific databases

CTDi6894
MGIiMGI:4936930 Tarbp1

Phylogenomic databases

eggNOGiKOG0839 Eukaryota
COG0566 LUCA
GeneTreeiENSGT00390000003939
InParanoidiE9Q368
KOiK15333
OMAiWFEAKLV
OrthoDBiEOG091G0UYQ
PhylomeDBiE9Q368
TreeFamiTF314976

Miscellaneous databases

ChiTaRSiTarbp1 mouse
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000090290 Expressed in 22 organ(s), highest expression level in thymus

Family and domain databases

Gene3Di3.40.1280.10, 1 hit
InterProiView protein in InterPro
IPR029028 Alpha/beta_knot_MTases
IPR016024 ARM-type_fold
IPR025806 Prob_MeTrfase_TARBP1
IPR001537 SpoU_MeTrfase
IPR029026 tRNA_m1G_MTases_N
PfamiView protein in Pfam
PF00588 SpoU_methylase, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit
SSF75217 SSF75217, 1 hit
PROSITEiView protein in PROSITE
PS51624 SAM_MT_TRMH_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE9Q368_MOUSE
AccessioniPrimary (citable) accession number: E9Q368
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: November 7, 2018
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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