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Entry version 67 (08 May 2019)
Sequence version 1 (05 Apr 2011)
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Protein

Cat eye syndrome critical region protein 2 homolog

Gene

Cecr2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Chromatin reader component of histone-modifying complexes, such as the CERF (CECR2-containing-remodeling factor) complex and ISWI-type complex (By similarity). It thereby plays a role in various processes during development: required during embryogenesis for neural tube closure and inner ear development (PubMed:15640247, PubMed:20589882, PubMed:21246654). In adults, required for spermatogenesis, via the formation of ISWI-type chromatin complexes (PubMed:22154806). In histone-modifying complexes, CECR2 recognizes and binds acylated histones: binds histones that are acetylated and/or butyrylated (By similarity). May also be involved through its interaction with LRPPRC in the integration of cytoskeletal network with vesicular trafficking, nucleocytosolic shuttling, transcription, chromosome remodeling and cytokinesis (By similarity).By similarity4 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionChromatin regulator

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Cat eye syndrome critical region protein 2 homolog
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Cecr2Imported
Synonyms:Kiaa17401 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1923799 Cecr2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Perinatal death with high penetrance due to cranial neural tube defects (PubMed:15640247, PubMed:20589882). Exencephaly is frequently associated by open eyelids (PubMed:20589882). Defects may be due to misregulation of mesenchymal/ectodermal transcription factors (PubMed:20589882). Fetuses also show specific inner ear defects, such as smaller cochleae as well as rotational defects of sensory cells and extra cell rows in the inner ear reminiscent of planar cell polarity (PCP) mutants (PubMed:21246654). Mutant males non-penetrant for neural tube defects produce smaller litters: mutants have normal seminiferous epithelium morphology, sperm count, motility and morphology, but the mutant spermatozoa are compromised in their ability to fertilize oocytes (PubMed:22154806).4 Publications

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004417751 – 1453Cat eye syndrome critical region protein 2 homologAdd BLAST1453

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei402PhosphoserineBy similarity1
Modified residuei526PhosphothreonineCombined sources1
Modified residuei551PhosphoserineBy similarity1
Modified residuei983PhosphoserineBy similarity1
Modified residuei1166Asymmetric dimethylarginineCombined sources1
Modified residuei1172Asymmetric dimethylarginineCombined sources1
Modified residuei1280PhosphoserineBy similarity1

Keywords - PTMi

Methylation, Phosphoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
E9Q2Z1

PeptideAtlas

More...
PeptideAtlasi
E9Q2Z1

PRoteomics IDEntifications database

More...
PRIDEi
E9Q2Z1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified ‘at the protein level’.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

In embryos, predominantly expressed in neural tissues (PubMed:15640247). Expressed throughout inner ear development: expressed in the neuroepithelium, head mesenchyme and the cochlear floor (PubMed:21246654).2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000071226 Expressed in 155 organ(s), highest expression level in secondary oocyte

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
E9QA25 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Part of the CECR2-containing remodeling factor (CERF) complex which contains CECR2 and SMARCA1. Interacts with acetylated lysine residues on histone H2A and H3 (in vitro). Interacts with LRPPRC.By similarity

Protein-protein interaction databases

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-454 CERF complex

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000108306

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
E9Q2Z1

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini431 – 501BromoPROSITE-ProRule annotationAdd BLAST71

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi619 – 947Pro-richPROSITE-ProRule annotationAdd BLAST329

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The Bromo domain recognizes and binds acetylated histones. Also recognizes and binds histones that are butyrylated.By similarity

Keywords - Domaini

Bromodomain

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1472 Eukaryota
COG5076 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000160360

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000081808

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
E9Q2Z1

Identification of Orthologs from Complete Genome Data

More...
OMAi
NHGATNP

Database of Orthologous Groups

More...
OrthoDBi
103411at2759

TreeFam database of animal gene trees

More...
TreeFami
TF324727

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.920.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001487 Bromodomain
IPR036427 Bromodomain-like_sf
IPR018359 Bromodomain_CS
IPR029614 CECR2

The PANTHER Classification System

More...
PANTHERi
PTHR47092 PTHR47092, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00439 Bromodomain, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00503 BROMODOMAIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00297 BROMO, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47370 SSF47370, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00633 BROMODOMAIN_1, 1 hit
PS50014 BROMODOMAIN_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: E9Q2Z1-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MCPEEGGAAG LGELRSWWEV PAIAHFCSLF RTAFRLPDFE IEELEAALHR
60 70 80 90 100
DDVEFISDLI ACLLQGCYQR RDITPQTFHS YLEDIINYRW ELEEGKPNPL
110 120 130 140 150
REASFQDLPL RTRVEILHRL CDYRLDADDV FDLLKGLDAD SLRVEPLGED
160 170 180 190 200
NSGALYWYFY GTRMYKEDPV QGRSNGELSL CRESERQKNV SNVPGKTGKR
210 220 230 240 250
RGRPPKRKKL QEEIISSEKQ EENSLTSDLQ TRNGSRGPGQ GTWWLLCQTE
260 270 280 290 300
EEWRQVTESF RERTSLRERQ LYKLLSEDFL PEICNMIAQK GKRPQRTKPE
310 320 330 340 350
LQHRFMSDHL SIKSIKLEET PMLTKIEKQK RREEEEERQL LLAVQKKEQE
360 370 380 390 400
QMLKEERKRE MEEKVKAVED RAKRRKLREE RAWLLAQGKE LPPELSHLDL
410 420 430 440 450
NSPMREGKKT KDLFELDDDF TAMYKVLDVV KAHKDSWPFL EPVDESYAPN
460 470 480 490 500
YYQIIKIPMD ISSMEKKLNG GLYCNKEEFV NDMKTMFRNC RKYNGDSSEY
510 520 530 540 550
TKMSDNLERC FHRAMTKHFP GEDGDTDEEF WIKEDEKREK RRSRSGRSSG
560 570 580 590 600
SHVWTRSRDT EGSSRKQPPV ENGGKSLPPA RRAASSGDDQ SRSSIQLPPE
610 620 630 640 650
VGTSHGQGFS RPLHCGRVPS HAPPLNQMRP AAPGTFGSLQ GSDPTNLHGS
660 670 680 690 700
SRIPEAPPGE PLQHPPFAIQ APVGISNHRG SLLSAPDLSN MGSHVPSLQL
710 720 730 740 750
GQMNCPSQDG NMYPPAPFQA GFIPSRHGGT PARPPDFPES SEIPPGHIYH
760 770 780 790 800
SYKYLNRAHP AVWNGNHGTT NPGRLGPDEK PHLGPGPSHH PHTLGHMMDG
810 820 830 840 850
RVMRQPIPPN QWTKQSSFLP HGVPSSGYMQ PPCKSAGHRL QPPPTPAPSP
860 870 880 890 900
RFRGPSQALR GAQGGESMMD SPEMIAMQQL SSRVCPPGVP YHPRQPTPPQ
910 920 930 940 950
LPGPFPQVAH SASVCVSAPK PALDNPGSTQ EMTETHEPEE DPAEPLPGHE
960 970 980 990 1000
EKAASICSSE GVYLKQLPHP APPLQASCTR QSSPQERETE DSQLKSDASD
1010 1020 1030 1040 1050
SADTYKTSKN KNTWPLDNSY SSPAVQGCLR DLSIVAETGN LPENGVVGEA
1060 1070 1080 1090 1100
SPCRSEGKGL DGSGSEKPLC PRGKTLQEAV PCTGPNATTP PCTDPSLMAA
1110 1120 1130 1140 1150
TVNQFSPLYM PGIEYSNSAT QYPMSPSLQG LASMMGGKSS GSQPQSFPPR
1160 1170 1180 1190 1200
GFQANGPHPG LFPRYRPQQG MRYSYQPPSQ PSYHPYQRTP YYTCPQGFSD
1210 1220 1230 1240 1250
WQRSLPSQRS PSGPPGSHPP RSLFSEKNVL SSLQGCETLN TALTSPTQMD
1260 1270 1280 1290 1300
VVTAKVVPPD GHNSGPEEEK MDESVERPES PKEFLDLDNH NAATKRQNSL
1310 1320 1330 1340 1350
STSDYLYGTP PPSLSSGMTF GSSAFPPHSV MLQTGSPYTP QRSASHFQPR
1360 1370 1380 1390 1400
AYPSPVPAHP PPHPVATQPN GLSPEDSLYC CQEEGLGHFQ ASMMEQTGTG
1410 1420 1430 1440 1450
SGLRGSFQEV HRPPGLQMHP VQSQSLFPKT PAPAASPEQL PPHKTPTLPL

DQS
Length:1,453
Mass (Da):161,530
Last modified:April 5, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iBCD9BA085DC40814
GO
Isoform 2 (identifier: E9Q2Z1-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     601-628: Missing.

Show »
Length:1,425
Mass (Da):158,579
Checksum:iE10E0FB0F99673C6
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_059110601 – 628Missing in isoform 2. Add BLAST28

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC084273 Genomic DNA No translation available.
AC135105 Genomic DNA No translation available.
AK129435 mRNA Translation: BAC98245.1
BC060152 mRNA Translation: AAH60152.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS51890.1 [E9Q2Z1-2]

NCBI Reference Sequences

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RefSeqi
NP_001121623.1, NM_001128151.1 [E9Q2Z1-2]
XP_006506383.1, XM_006506320.1 [E9Q2Z1-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000100993; ENSMUSP00000098556; ENSMUSG00000071226 [E9Q2Z1-1]
ENSMUST00000112686; ENSMUSP00000108306; ENSMUSG00000071226 [E9Q2Z1-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
330409

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:330409

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC084273 Genomic DNA No translation available.
AC135105 Genomic DNA No translation available.
AK129435 mRNA Translation: BAC98245.1
BC060152 mRNA Translation: AAH60152.1
CCDSiCCDS51890.1 [E9Q2Z1-2]
RefSeqiNP_001121623.1, NM_001128151.1 [E9Q2Z1-2]
XP_006506383.1, XM_006506320.1 [E9Q2Z1-1]

3D structure databases

SMRiE9Q2Z1
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

ComplexPortaliCPX-454 CERF complex
STRINGi10090.ENSMUSP00000108306

Proteomic databases

MaxQBiE9Q2Z1
PeptideAtlasiE9Q2Z1
PRIDEiE9Q2Z1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000100993; ENSMUSP00000098556; ENSMUSG00000071226 [E9Q2Z1-1]
ENSMUST00000112686; ENSMUSP00000108306; ENSMUSG00000071226 [E9Q2Z1-2]
GeneIDi330409
KEGGimmu:330409

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
27443
MGIiMGI:1923799 Cecr2

Rodent Unidentified Gene-Encoded large proteins database

More...
Rougei
Search...

Phylogenomic databases

eggNOGiKOG1472 Eukaryota
COG5076 LUCA
GeneTreeiENSGT00940000160360
HOGENOMiHOG000081808
InParanoidiE9Q2Z1
OMAiNHGATNP
OrthoDBi103411at2759
TreeFamiTF324727

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Cecr2 mouse

Protein Ontology

More...
PROi
PR:E9Q2Z1

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000071226 Expressed in 155 organ(s), highest expression level in secondary oocyte
GenevisibleiE9QA25 MM

Family and domain databases

Gene3Di1.20.920.10, 1 hit
InterProiView protein in InterPro
IPR001487 Bromodomain
IPR036427 Bromodomain-like_sf
IPR018359 Bromodomain_CS
IPR029614 CECR2
PANTHERiPTHR47092 PTHR47092, 1 hit
PfamiView protein in Pfam
PF00439 Bromodomain, 1 hit
PRINTSiPR00503 BROMODOMAIN
SMARTiView protein in SMART
SM00297 BROMO, 1 hit
SUPFAMiSSF47370 SSF47370, 1 hit
PROSITEiView protein in PROSITE
PS00633 BROMODOMAIN_1, 1 hit
PS50014 BROMODOMAIN_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCECR2_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E9Q2Z1
Secondary accession number(s): E9QA25
, F6VR46, F7B218, Q6PAQ2, Q6ZPI9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 25, 2017
Last sequence update: April 5, 2011
Last modified: May 8, 2019
This is version 67 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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