Slc19a2

Functionⁱ

GO - Molecular functionⁱ

thiamine transmembrane transporter activity Source: Ensembl

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

thiamine transport Source: Ensembl

View the complete GO annotation on QuickGO ...

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Thiamine transporter 1Imported
Gene namesⁱ	Name:Slc19a2Imported
Organismⁱ	Mus musculus (Mouse)Imported
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 1

Organism-specific databases

MGIⁱ	MGI:1928761 Slc19a2

Subcellular locationⁱ

GO - Cellular component

Topology

Feature key	Position(s)	DescriptionActions	Length
Transmembraneⁱ	95 – 112	HelicalSequence analysisAdd BLAST	18
Transmembraneⁱ	132 – 154	HelicalSequence analysisAdd BLAST	23
Transmembraneⁱ	161 – 179	HelicalSequence analysisAdd BLAST	19
Transmembraneⁱ	185 – 209	HelicalSequence analysisAdd BLAST	25
Transmembraneⁱ	221 – 243	HelicalSequence analysisAdd BLAST	23
Transmembraneⁱ	255 – 276	HelicalSequence analysisAdd BLAST	22

Keywords - Cellular componentⁱ

Membrane

PTM / Processingⁱ

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	E9Q2R3
PRIDEⁱ	E9Q2R3

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSMUSG00000040918 Expressed in 248 organ(s), highest expression level in cornea
ExpressionAtlasⁱ	E9Q2R3 baseline and differential

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	E9Q2R3
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Keywords - Domainⁱ

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGⁱ	KOG3810 Eukaryota ENOG410XT34 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00510000046382

Family and domain databases

InterProⁱ	View protein in InterPro IPR002666 Folate_carrier IPR036259 MFS_trans_sf
PANTHERⁱ	PTHR10686 PTHR10686, 2 hits
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF01770 Folate_carrier, 1 hit
SUPFAMⁱ	SSF103473 SSF103473, 1 hit

Sequence (1+)ⁱ

Sequence statusⁱ: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show all Align All

E9Q2R3-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MDVPARVSRR AAAAAARMLL RTARVPRECW FLPTALLCAY GFFANLRPSE 
        60         70         80         90        100
PFLTPYLLGP DKNLTERQEE PKPDRLRVFR VLWNDFLMCY SSRPLLCWSV 
       110        120        130        140        150
WWALSTCGYF QVVNYAQGLW EKVMPSQNAD IYNGGVEAVS TLLGASAVFA 
       160        170        180        190        200
VGYIKLSWST WGEMTLFLCS LLIAAAVYVM DTVQSIWVCY ASYVVFRIIY 
       210        220        230        240        250
MVLITIATFQ IAANLSMERY ALVFGVNTFI ALALQTLLTL IVVDARGLGL 
       260        270        280        290 
CITTQFLIYA SYFAAISVVF LANGIVSIIK KCRKQEDPSS SPQASTS

Length:297

Mass (Da):33,200

Last modified:April 5, 2011 - v1

Checksum:ⁱ84C2DA49C839FEC0

GO

Computationally mapped potential isoform sequencesⁱ

There is 1 potential isoform mapped to this entry.BLAST Align Show all Add to basket

	Entry	Entry name		Protein names	Gene names	Length	Annotation

	Q9EQN9	S19A2_MOUSE		Thiamine transporter 1 Thiamine transporter 1, ThTr-1 (Solute carrier family 19 member 2)	Slc19a2	498	Annotation score:

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC105161 Genomic DNA No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AC105161 Genomic DNA No translation available.

Genome annotation databases

Ensemblⁱ	ENSMUST00000169394; ENSMUSP00000131327; ENSMUSG00000040918

Ensemblⁱ

ENSMUST00000169394; ENSMUSP00000131327; ENSMUSG00000040918

Protein	Similar proteins		Species	Score	Length	Source
E9Q2R3	Solute carrier family 19 member 2 (Fragment)		RAT		256	UniRef90_A0A096MJN0
UPI000A309FCA		MUSPA		296

Protein	Similar proteins		Species	Score	Length	Source
E9Q2R3	Solute carrier family 19 member 2 (Fragment)		RAT		256	UniRef50_A0A096MJN0
Uncharacterized protein		RHIBE		294
Solute carrier family 19 member 2		SAIBB		297
Uncharacterized protein		Cebus capucinus imitator		297
Uncharacterized protein		AOTNA		297
+30

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC105161 Genomic DNA No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AC105161 Genomic DNA No translation available.

3D structure databases

ProteinModelPortalⁱ	E9Q2R3
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Proteomic databases

MaxQBⁱ	E9Q2R3
PRIDEⁱ	E9Q2R3

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000169394; ENSMUSP00000131327; ENSMUSG00000040918

Ensemblⁱ

ENSMUST00000169394; ENSMUSP00000131327; ENSMUSG00000040918

Organism-specific databases

MGIⁱ	MGI:1928761 Slc19a2

Phylogenomic databases

eggNOGⁱ	KOG3810 Eukaryota ENOG410XT34 LUCA
GeneTreeⁱ	ENSGT00510000046382

Miscellaneous databases

SOURCEⁱ	Search...

SOURCEⁱ

Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000040918 Expressed in 248 organ(s), highest expression level in cornea
ExpressionAtlasⁱ	E9Q2R3 baseline and differential

Family and domain databases

InterProⁱ	View protein in InterPro IPR002666 Folate_carrier IPR036259 MFS_trans_sf
PANTHERⁱ	PTHR10686 PTHR10686, 2 hits
Pfamⁱ	View protein in Pfam PF01770 Folate_carrier, 1 hit
SUPFAMⁱ	SSF103473 SSF103473, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	E9Q2R3_MOUSE
Accessionⁱ	E9Q2R3Primary (citable) accession number: E9Q2R3
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	April 5, 2011
	Last sequence update:	April 5, 2011
	Last modified:	September 12, 2018
	This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - E9Q2R3 (E9Q2R3_MOUSE)

Your basket is currently empty. i <p>When browsing through different UniProt proteins, you can use the ‘basket’ to save them, so that you can back to find or analyse them later.<p><a href='/help/basket' target='_top'>More...</a></p>

Thiamine transporter 1

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Plasma Membrane

Other locations

Topology

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

UniProt is an ELIXIR core data resource

Your basket is currently empty. ⁱ

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

PTM / Processingⁱ

Expressionⁱ

Structureⁱ

Family & Domainsⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ