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UniProtKB - E9Q2P5 (E9Q2P5_MOUSE)
Protein
Submitted name:
Serine/threonine-protein kinase ULK4
Gene
Ulk4
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- ATP binding Source: InterPro
- protein kinase activity Source: InterPro
GO - Biological processi
- microtubule cytoskeleton organization Source: Ensembl
- regulation of JNK cascade Source: Ensembl
- regulation of neuron migration Source: Ensembl
- regulation of neuron projection development Source: Ensembl
- regulation of p38MAPK cascade Source: Ensembl
- regulation of protein kinase C signaling Source: Ensembl
Names & Taxonomyi
Protein namesi | Submitted name: Serine/threonine-protein kinase ULK4Imported |
Gene namesi | Name:Ulk4Imported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:1921622, Ulk4 |
VEuPathDBi | HostDB:ENSMUSG00000040936 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000040936, Expressed in spermatid and 130 other tissues |
ExpressionAtlasi | E9Q2P5, baseline and differential |
Genevisiblei | E9Q2P5, MM |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 4 – 280 | Protein kinaseInterPro annotationAdd BLAST | 277 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 304 – 332 | DisorderedSequence analysisAdd BLAST | 29 | |
Regioni | 369 – 401 | DisorderedSequence analysisAdd BLAST | 33 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 313 – 332 | Polar residuesSequence analysisAdd BLAST | 20 | |
Compositional biasi | 382 – 401 | Polar residuesSequence analysisAdd BLAST | 20 |
Phylogenomic databases
GeneTreei | ENSGT00940000156541 |
OMAi | NWYETNN |
OrthoDBi | 219167at2759 |
PhylomeDBi | E9Q2P5 |
TreeFami | TF332678 |
Family and domain databases
Gene3Di | 1.25.10.10, 2 hits |
InterProi | View protein in InterPro IPR011989, ARM-like IPR016024, ARM-type_fold IPR011009, Kinase-like_dom_sf IPR000719, Prot_kinase_dom IPR045906, ULK4 |
PANTHERi | PTHR46240, PTHR46240, 1 hit |
Pfami | View protein in Pfam PF00069, Pkinase, 1 hit |
SUPFAMi | SSF48371, SSF48371, 1 hit SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS50011, PROTEIN_KINASE_DOM, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All
E9Q2P5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MENFVLYEEI GRGSRTVVYK GRRKGTINFV AILCTEKCKR PEITNWVRLT
60 70 80 90 100
HEIKHKNIVT FHEWYETSNH LWLVVELCTG GSLETVIAQD ENLPEDVVRE
110 120 130 140 150
FGVDLVTGLH HLHRLGILFC DLSPGKILLE GPGTLKFSNF CLAKVAGESL
160 170 180 190 200
EEFFALVAAE EGGGDSGENA LKKSMKTRVR GSLIYAAPEI VKGTEFSVTS
210 220 230 240 250
DLWSLGCLLY EMFSGKPPFF SETVSELVEK ILYEDPLPPI PKDSSFPKAS
260 270 280 290 300
SDFLNLLDGL LQKDPQKRFS WEGVLQHPFW KDALRGEDSG WASEDSPFSR
310 320 330 340 350
NVMECSGPHD SRELLQSPKN GQAKGQKAAH RLSQSFRLEN PTELRPKSIM
360 370 380 390 400
GGQLNESIFL LSSRPTPRTS AMVELNPGEG EDPSSPQKTS PLSKMTSGHL
410 420 430 440 450
SQGALESQMR ELIYTDSDLV ITPIIDNPKI MKQPAIKFDP KILHLPAYSV
460 470 480 490 500
EKLLVLKDQD WNDFLQQVCS QIDSSEKSTG ALRAKLNLLC YLCVVATHKE
510 520 530 540 550
VATRLLHSPL FQLLIQHLRI APNWDIRSKV ARVVGMLALH TTELQENVPV
560 570 580 590 600
IEAITLLTEL IRENFRSGKL KQCLLPTLGQ LLYLVATQEE KNQHSRDCWA
610 620 630 640 650
VPLAAYTVLM RCLREGEERV VNHMAAKIIE NVCTTFSAQA QGFTTGEIGP
660 670 680 690 700
VLWHLFRHST VDALRITAIS ALCRITRQSP TAFQNVIEKV GLNAVISSLA
710 720 730 740 750
SAICKVQQYM LTLFTAMLSC GIHLQRLIQE KDFVSTVIRL LDSPSTPIRA
760 770 780 790 800
KAFLVLLYIL IHNRDMLLLS CQARLVMYIE RDSRKTSPGK EQQSGNEYLA
810 820 830 840 850
RCLDLLIQHM VQEPPRILGD ILNALANVSG RKHPSTVQGK QLKMCLPMMP
860 870 880 890 900
VVLHLVMSQV FRPQVVTEEF LFSYGTILSH IKSIDLGETN IDGAIGIVAS
910 920 930 940 950
EEFIKVTLSA FEAVIQYPVL LADYRSTVMD YILPPLVSLV QSQNVEWRLF
960 970 980 990 1000
SLRLLSETTT LLVSQEPEDG DEEASCDSDS SLLALIRDEL LPQYEHILME
1010 1020 1030 1040 1050
PDPVPAYALK LLVAMTEHNP AFTRLVEESK LVPLIFEVIL EHQESILGNT
1060 1070 1080 1090 1100
MQSVIALLNN LVAYKDSNMQ LLYEQGLVGH VCNMFTETAT LCLDRDNKTN
1110 1120 1130 1140 1150
TEPASTLLAS LLDILLGMLT YTSRIVRQAL QVQKSGSRGD TQAAEDLLLL
1160 1170 1180 1190 1200
SKPLTDLISL LIPLLPSEDP EISEVSSKCL SILVQLYGGE NPESLSPENM
1210 1220 1230 1240 1250
VTFANLLMTK EDPKDQKLLL RILKRMVTSN ERLLESLKNT GSLLQALERL
1260 1270
APAHSSPVDT IVASLALELL QAVGH
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ3V129 | ULK4_MOUSE | Serine/threonine-protein kinase ULK... | Ulk4 | 1,303 | Annotation score: | ||
E9QKJ7 | E9QKJ7_MOUSE | Serine/threonine-protein kinase ULK... | Ulk4 | 1,188 | Annotation score: | ||
E9Q220 | E9Q220_MOUSE | Serine/threonine-protein kinase ULK... | Ulk4 | 139 | Annotation score: | ||
H7BX20 | H7BX20_MOUSE | Serine/threonine-protein kinase ULK... | Ulk4 | 54 | Annotation score: |
Sequence databases
RefSeqi | NP_808257.2, NM_177589.3 |
Genome annotation databases
Ensembli | ENSMUST00000171923; ENSMUSP00000131342; ENSMUSG00000040936 |
GeneIDi | 209012 |
KEGGi | mmu:209012 |
UCSCi | uc012hco.1, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
RefSeqi | NP_808257.2, NM_177589.3 |
3D structure databases
SMRi | E9Q2P5 |
ModBasei | Search... |
Proteomic databases
MaxQBi | E9Q2P5 |
ProteomicsDBi | 359765 |
Protocols and materials databases
Antibodypediai | 6576, 109 antibodies from 27 providers |
Genome annotation databases
Ensembli | ENSMUST00000171923; ENSMUSP00000131342; ENSMUSG00000040936 |
GeneIDi | 209012 |
KEGGi | mmu:209012 |
UCSCi | uc012hco.1, mouse |
Organism-specific databases
CTDi | 54986 |
MGIi | MGI:1921622, Ulk4 |
VEuPathDBi | HostDB:ENSMUSG00000040936 |
Phylogenomic databases
GeneTreei | ENSGT00940000156541 |
OMAi | NWYETNN |
OrthoDBi | 219167at2759 |
PhylomeDBi | E9Q2P5 |
TreeFami | TF332678 |
Miscellaneous databases
BioGRID-ORCSi | 209012, 1 hit in 65 CRISPR screens |
ChiTaRSi | Ulk4, mouse |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000040936, Expressed in spermatid and 130 other tissues |
ExpressionAtlasi | E9Q2P5, baseline and differential |
Genevisiblei | E9Q2P5, MM |
Family and domain databases
Gene3Di | 1.25.10.10, 2 hits |
InterProi | View protein in InterPro IPR011989, ARM-like IPR016024, ARM-type_fold IPR011009, Kinase-like_dom_sf IPR000719, Prot_kinase_dom IPR045906, ULK4 |
PANTHERi | PTHR46240, PTHR46240, 1 hit |
Pfami | View protein in Pfam PF00069, Pkinase, 1 hit |
SUPFAMi | SSF48371, SSF48371, 1 hit SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS50011, PROTEIN_KINASE_DOM, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | E9Q2P5_MOUSE | |
Accessioni | E9Q2P5Primary (citable) accession number: E9Q2P5 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 5, 2011 |
Last sequence update: | April 5, 2011 | |
Last modified: | January 19, 2022 | |
This is version 81 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |