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Protein
Submitted name:

Chloride channel protein 1

Gene

Clcn1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Chloride channel protein 1Imported
Gene namesi
Name:Clcn1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 6

Organism-specific databases

MGIiMGI:88417 Clcn1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei118 – 139HelicalSequence analysisAdd BLAST22
Transmembranei159 – 182HelicalSequence analysisAdd BLAST24
Transmembranei203 – 223HelicalSequence analysisAdd BLAST21
Transmembranei235 – 257HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PRIDEiE9Q2N3

Expressioni

Gene expression databases

BgeeiENSMUSG00000029862 Expressed in 79 organ(s), highest expression level in skeletal muscle tissue
ExpressionAtlasiE9Q2N3 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliE9Q2N3
SMRiE9Q2N3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0476 Eukaryota
COG0038 LUCA
GeneTreeiENSGT00760000119109

Family and domain databases

Gene3Di1.10.3080.10, 1 hit
InterProiView protein in InterPro
IPR014743 Cl-channel_core
IPR001807 Cl-channel_volt-gated
IPR002243 Cl_channel-1
PfamiView protein in Pfam
PF00654 Voltage_CLC, 1 hit
PRINTSiPR00762 CLCHANNEL
PR01112 CLCHANNEL1
SUPFAMiSSF81340 SSF81340, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.iShow all

E9Q2N3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MERSQSQRHG GEQSWWGSAP QYQYMPFEHC TSYGLPSENG GLQHRPRKDM
60 70 80 90 100
GPRHNAHPTQ IYGHQKEQYS YKAQDGGMPK KMGSSSTMDS LDEDHYSKCQ
110 120 130 140 150
DCVHRLGRVL RRKLGEDWIF LVLLGLLMAL VSWCMDYVSA KSLQAYKWTY
160 170 180 190 200
AQMKPSLPLQ YLAWVTFPLI LILFSALFCQ LISPQAVGSG IPEMKTILRG
210 220 230 240 250
VVLKEYLTLK AFVAKVVALT AGLGSGIPVG KEGPFVHIAS ICAAVLSKFM

SMFSGVYE
Length:258
Mass (Da):28,906
Last modified:April 5, 2011 - v1
Checksum:iBB003376BBBFAE25
GO

Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q64347CLCN1_MOUSE
Chloride channel protein 1
Clcn1 Clc1
994Annotation score:
F6QI82F6QI82_MOUSE
Chloride channel protein
Clcn1
923Annotation score:
F6QL23F6QL23_MOUSE
Chloride channel protein 1
Clcn1
229Annotation score:
F6X177F6X177_MOUSE
Chloride channel protein 1
Clcn1
289Annotation score:
F7A9J6F7A9J6_MOUSE
Chloride channel protein 1
Clcn1
257Annotation score:
F7C9S1F7C9S1_MOUSE
Chloride channel protein 1
Clcn1
262Annotation score:
F6VSA8F6VSA8_MOUSE
Chloride channel protein 1
Clcn1
104Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC153915 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSMUST00000164091; ENSMUSP00000131354; ENSMUSG00000029862

Similar proteinsi

Entry informationi

Entry nameiE9Q2N3_MOUSE
AccessioniPrimary (citable) accession number: E9Q2N3
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: September 12, 2018
This is version 46 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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