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Entry version 57 (08 May 2019)
Sequence version 1 (05 Apr 2011)
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Protein

Little elongation complex subunit 1

Gene

Ice1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III. Specifically acts as a scaffold protein that promotes the LEC complex formation and recruitment and RNA polymerase II occupancy at snRNA genes in subnuclear bodies (By similarity).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processTranscription, Transcription regulation

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-6807505 RNA polymerase II transcribes snRNA genes

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Little elongation complex subunit 1
Alternative name(s):
Interactor of little elongator complex ELL subunit 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Ice1
Synonyms:Kiaa0947
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 13

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2385865 Ice1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004304231 – 2241Little elongation complex subunit 1Add BLAST2241

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei523PhosphoserineBy similarity1
Modified residuei676PhosphoserineCombined sources1
Modified residuei803PhosphothreonineBy similarity1
Modified residuei896PhosphoserineBy similarity1
Modified residuei1189N6-acetyllysineBy similarity1
Modified residuei1553PhosphoserineBy similarity1
Modified residuei1582PhosphoserineCombined sources1
Modified residuei1607PhosphothreonineCombined sources1
Modified residuei1657PhosphoserineBy similarity1
Modified residuei1662PhosphoserineBy similarity1
Modified residuei1664PhosphoserineBy similarity1
Modified residuei1666PhosphoserineBy similarity1
Modified residuei1677PhosphoserineBy similarity1
Modified residuei1820PhosphoserineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
E9Q286

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
E9Q286

MaxQB - The MaxQuant DataBase

More...
MaxQBi
E9Q286

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
E9Q286

PeptideAtlas

More...
PeptideAtlasi
E9Q286

PRoteomics IDEntifications database

More...
PRIDEi
E9Q286

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
E9Q286

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
E9Q286

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000034525 Expressed in 286 organ(s), highest expression level in embryo

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
E9Q286 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
E9Q286 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the little elongation complex (LEC), at least composed of ELL (ELL, ELL2 or ELL3), ZC3H8, ICE1 and ICE2. Interacts (via N-terminus domain) with ELL. Interacts (via C-terminus domain) with ICE2 and ZC3H8 (By similarity).By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
230020, 4 interactors

Protein interaction database and analysis system

More...
IntActi
E9Q286, 2 interactors

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000036482

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
E9Q286

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili22 – 185Sequence analysisAdd BLAST164

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi593 – 596Poly-Ala4
Compositional biasi606 – 609Poly-Ser4
Compositional biasi820 – 823Poly-Ala4
Compositional biasi1595 – 1665Pro-richAdd BLAST71

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The N-termimus domain is necessary and sufficient for its targeting to subnuclear cajal and histone locus bodies.By similarity

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the ICE1 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IE47 Eukaryota
ENOG4111F6B LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000183199

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000168419

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
E9Q286

Identification of Orthologs from Complete Genome Data

More...
OMAi
GQISPLC

Database of Orthologous Groups

More...
OrthoDBi
265329at2759

TreeFam database of animal gene trees

More...
TreeFami
TF330760

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

E9Q286-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMPGETHPAA PGPADLARCQ GCASLQQNLN EYVEALIALK QKIINTDNLL
60 70 80 90 100
TEYQKKCDEL QFARRENSTL HHQVEQMLQK ISPLQKCQEE LGSLKAELEE
110 120 130 140 150
KKSSLKLYQD THQEYARVKE ECLRTDAQKK KLEAKVKKLE EAAVKQTQDF
160 170 180 190 200
KQLRNEKKIL EKEFKKTQER LDEFSKQKNE KELRHIGTQI SSDSHGSIDK
210 220 230 240 250
RKVKVLLKEL WLCVNTAHRL SGEGGRRIPE KPAKGSSAAR ASEQDELLPV
260 270 280 290 300
QGGPARAADM RSFFSKLSME MEGDFSSSES AEEELPSGAS PSTEHAFCEE
310 320 330 340 350
RHSEVSGQRP DDGNRTNVYD HEHFFDDDLQ AAIDFFKLPP PLLSPVPSPP
360 370 380 390 400
PMASGSLPSS LAPESFFGEF TDSSDSDSVP PRDSMESALE DYTAESRAYF
410 420 430 440 450
DLLEKIKRSD QYVKKPGSLE ATQAVNSLTP LGFVTGRTAL GEPSAAASLA
460 470 480 490 500
QGRHWTESSE FVRDRGDSVE EAERMVEARE VDKSVQVGKG LLKHNRKLWL
510 520 530 540 550
EMASRGPARK KEAGAGESEI CFSSLGKRTF SELIESEGKT LSSKALCPSQ
560 570 580 590 600
SEFSKRTLTD GSASKSPCVT GSGRFQRRER DVRESTPQSG ICAAAAGRGH
610 620 630 640 650
SARLPSSSSA TSVPVSVCSN HQTPWPGCVS VGTPAEGTCT EQKSPTRTLN
660 670 680 690 700
TFLLRSEPTA CFPKENDPEN SLSTLSPKSK LGTSTFSDWK SRGLESFSTL
710 720 730 740 750
KSTAKGHSLP QSVFPKPTGG GQCKGRGPGA TLILPKSDWT SLARSQAGFT
760 770 780 790 800
RRSSGSADST SWHRSDVLRR GSGGSPRASS EYQQRTRLQL EKATPASQNS
810 820 830 840 850
SLTAMHGPSG ESTIPPESNA AAALLPNQVS VITKQARPRR VLGSSLEPWQ
860 870 880 890 900
PHGNTLSPAV NGGKETGLMP SVSACVGDGD PIAQVPEQIA DKETPSPEVS
910 920 930 940 950
VSWRNPICDS PSDSLLAENF SCSTDRKLPF SSEDNIFQCA MNEHLQQKPT
960 970 980 990 1000
KSPQTTQSGA SRLEAGELLP SGVTSGVFPA EQVPHGPHHQ ADTEAPVVAR
1010 1020 1030 1040 1050
ESHSAPQNAS APPVVPSRGP LRARVPTVPV CPSSLSRAEE ETQGTSQSSL
1060 1070 1080 1090 1100
PGASYCYTGI RERGEEDTEV EDEAVSCSEG EHEAEAVMGR RQQEQAEDSH
1110 1120 1130 1140 1150
RPLGDPEAGV GEAGHPSDVG DLTSALEECN LSTLLYIDKL STSEVVMVLE
1160 1170 1180 1190 1200
SCQLGDYSSR VSASECASKG SLSEEMNTEL RQSEISRKKC GKRLWEEKLL
1210 1220 1230 1240 1250
RASEEWAESE GDDSCGRTSC QHAQCPLEVP SDVLTKTGEE LDTNPVDCGG
1260 1270 1280 1290 1300
TDTEHALLES THHSQAAEDL TEDALPEETS SPMPHTAELP DPSAVDGGGS
1310 1320 1330 1340 1350
SPLSSRSDPE HIQSSYEDEP NSGECLSIGE EGLAEPGELL TLSSDSSTPP
1360 1370 1380 1390 1400
RLEQSSDCVA ETAFRYQISA VTSEVISVLI NKDQDLVIEK GDNWTIISGV
1410 1420 1430 1440 1450
AISPGMEQVV LCDTLGDAAS SQDQGGLDDG SMEKSPEASP SGPLPQEPPC
1460 1470 1480 1490 1500
GGDLSGAQED ISSNGQSANF DKSRLRNRPV KPSIWIRSQI YDQTLETEKV
1510 1520 1530 1540 1550
ASDHTYYNWK LEPLGKNKPR SKISNKDQAS KLAKTLVLNR GEVHLNEVPQ
1560 1570 1580 1590 1600
PASGEGTNIK LPRSQAQPIM AGTDRSTPTN CSPDTLSKIR QEVGPPLPPL
1610 1620 1630 1640 1650
LPPLIATPPR SSQTLSPLVP NSGPSSRSSP AGHVSPLCEV PGPPVLSPWP
1660 1670 1680 1690 1700
EELQQASPLD PSPSPSTAAA SGRIVSSPLQ FCAATPKHAL PVPGRLPSCA
1710 1720 1730 1740 1750
PGHAAVSGPQ QENSVKILDT MYPELSARAR TLSLLKGNMQ LSRGSTVDGK
1760 1770 1780 1790 1800
VLPGRVSALL GLKAITSTST AFVLTGGSSG ADGSQGKSQD SGVQQDAGGK
1810 1820 1830 1840 1850
RTLAVSMLRS AKRLRLDNKS PEPDTREVTG EGVPEDPQGG SPLAEVVPAE
1860 1870 1880 1890 1900
EEQADVPVCS AASLLRVNPR EMAESYNIAI TRALRKIAES SFDLLPVIRS
1910 1920 1930 1940 1950
HVYVGNISKK PVMRDQEKEV VYEFSTTNKH LGEYLLRSIL SELKIQKTSL
1960 1970 1980 1990 2000
DHSYIHALCR VYVGICRQLG DLERARLFCY SLLKEDFPES EKLTLFIANM
2010 2020 2030 2040 2050
WREVFLSQSA ISEAMQLVAR QRARGEVLNC LRAFLSWEKN APIDVGIVVS
2060 2070 2080 2090 2100
KLLLTIQLCP KTEFQSSEEF GEDLSANIWE YIFAIDLLCC HQRWIWTHDN
2110 2120 2130 2140 2150
IISKELWPVM DKWIKYRKGH SNIAYTPDVI VASVLRLIGR LGQLGLKEGF
2160 2170 2180 2190 2200
PTAVKNISSV IGMFIQHAQD EDIPWGVQLA AVYALCDLSP SNPAEISKIL
2210 2220 2230 2240
EAWRTQTSNA IPSAIVHCLE EVGSLSADGS AGCTSKGDSA P
Length:2,241
Mass (Da):242,254
Last modified:April 5, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i92C55F104302D8E0
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1Y7VML5A0A1Y7VML5_MOUSE
Little elongation complex subunit 1
Ice1
79Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1Y7VMN3A0A1Y7VMN3_MOUSE
Little elongation complex subunit 1
Ice1
130Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1Y7VK08A0A1Y7VK08_MOUSE
Little elongation complex subunit 1
Ice1
29Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1Y7VIN0A0A1Y7VIN0_MOUSE
Little elongation complex subunit 1
Ice1
117Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1Y7VKA7A0A1Y7VKA7_MOUSE
Little elongation complex subunit 1
Ice1
107Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC113508 Genomic DNA No translation available.
AK129244 mRNA Translation: BAC98054.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS49309.1

NCBI Reference Sequences

More...
RefSeqi
NP_659086.2, NM_144837.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000043493; ENSMUSP00000036482; ENSMUSG00000034525

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
218333

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:218333

UCSC genome browser

More...
UCSCi
uc007rcx.2 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC113508 Genomic DNA No translation available.
AK129244 mRNA Translation: BAC98054.1
CCDSiCCDS49309.1
RefSeqiNP_659086.2, NM_144837.3

3D structure databases

SMRiE9Q286
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi230020, 4 interactors
IntActiE9Q286, 2 interactors
STRINGi10090.ENSMUSP00000036482

PTM databases

iPTMnetiE9Q286
PhosphoSitePlusiE9Q286

Proteomic databases

EPDiE9Q286
jPOSTiE9Q286
MaxQBiE9Q286
PaxDbiE9Q286
PeptideAtlasiE9Q286
PRIDEiE9Q286

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000043493; ENSMUSP00000036482; ENSMUSG00000034525
GeneIDi218333
KEGGimmu:218333
UCSCiuc007rcx.2 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
23379
MGIiMGI:2385865 Ice1

Rodent Unidentified Gene-Encoded large proteins database

More...
Rougei
Search...

Phylogenomic databases

eggNOGiENOG410IE47 Eukaryota
ENOG4111F6B LUCA
GeneTreeiENSGT00950000183199
HOGENOMiHOG000168419
InParanoidiE9Q286
OMAiGQISPLC
OrthoDBi265329at2759
TreeFamiTF330760

Enzyme and pathway databases

ReactomeiR-MMU-6807505 RNA polymerase II transcribes snRNA genes

Miscellaneous databases

Protein Ontology

More...
PROi
PR:E9Q286

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000034525 Expressed in 286 organ(s), highest expression level in embryo
ExpressionAtlasiE9Q286 baseline and differential
GenevisibleiE9Q286 MM

Family and domain databases

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiICE1_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E9Q286
Secondary accession number(s): Q6ZQ20
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 2014
Last sequence update: April 5, 2011
Last modified: May 8, 2019
This is version 57 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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