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Protein
Submitted name:

Keratin 83

Gene

Krt83

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-MMU-6805567 Keratinization
R-MMU-6809371 Formation of the cornified envelope

Names & Taxonomyi

Protein namesi
Submitted name:
Keratin 83Imported
Gene namesi
Name:Krt83Imported
Synonyms:5430421N21RikImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 15

Organism-specific databases

MGIiMGI:3690448 Krt83

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Intermediate filamentPROSITE-ProRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

MaxQBiE9Q1Y9
PaxDbiE9Q1Y9
PeptideAtlasiE9Q1Y9
PRIDEiE9Q1Y9

PTM databases

iPTMnetiE9Q1Y9
PhosphoSitePlusiE9Q1Y9

Expressioni

Gene expression databases

BgeeiENSMUSG00000067613 Expressed in 71 organ(s), highest expression level in skin of back
GenevisibleiE9Q1Y9 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000023718

Structurei

3D structure databases

ProteinModelPortaliE9Q1Y9
SMRiE9Q1Y9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini104 – 415IF rodInterPro annotationAdd BLAST312

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili157 – 177Sequence analysisAdd BLAST21
Coiled coili185 – 205Sequence analysisAdd BLAST21
Coiled coili213 – 240Sequence analysisAdd BLAST28
Coiled coili313 – 354Sequence analysisAdd BLAST42
Coiled coili359 – 393Sequence analysisAdd BLAST35

Sequence similaritiesi

Belongs to the intermediate filament family.PROSITE-ProRule annotationSAAS annotation

Keywords - Domaini

Coiled coilPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG410IH1H Eukaryota
ENOG41113GZ LUCA
GeneTreeiENSGT00910000144006
InParanoidiE9Q1Y9
KOiK07605
OMAiCGFSTVG
OrthoDBiEOG091G06FG
PhylomeDBiE9Q1Y9
TreeFamiTF317854

Family and domain databases

InterProiView protein in InterPro
IPR001664 IF
IPR018039 IF_conserved
IPR039008 IF_rod_dom
IPR032444 Keratin_2_head
IPR003054 Keratin_II
PANTHERiPTHR23239 PTHR23239, 1 hit
PfamiView protein in Pfam
PF00038 Filament, 1 hit
PF16208 Keratin_2_head, 1 hit
PRINTSiPR01276 TYPE2KERATIN
SMARTiView protein in SMART
SM01391 Filament, 1 hit
PROSITEiView protein in PROSITE
PS00226 IF_ROD_1, 1 hit
PS51842 IF_ROD_2, 1 hit

Sequencei

Sequence statusi: Complete.

E9Q1Y9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTCGFRTGNF SCASACGPRP GRCCISAAPY RGISCYRGLS GGFGSQSVCG
60 70 80 90 100
AFRSGSCGRS FGYRSGGICG PSPPCITTVS VNESLLTPLN LEIDPNAQCV
110 120 130 140 150
KHEEKEQIKC LNSRFAAFID KVRFLEQQNK LLETKWQFYQ NRKCCESNME
160 170 180 190 200
PLFEGYIETL RREAECVEAD SGRLAAELNH AQESMEGYKK RYEEEVALRA
210 220 230 240 250
TAENEFVALK KDVDCAYLRK SDLEANAEAL TQETDFLRRM YDEETRILHS
260 270 280 290 300
HISDTSVIVK MDNSRDLNMD CVVAEIKAQY DDIASRSRAE AESWYRTKCE
310 320 330 340 350
EMKATVIRHG ETLRRTREEI NELNRMIQRL TAEIENAKCQ NTKLEAAVTQ
360 370 380 390 400
SEQQGEAALA DARCKLAELE GALQKAKQDM ACLLKEYQEV MNSKLGLDVE
410 420 430 440 450
IITYRRLLEG EEQRLCEGVG AVNVCVSSSR GGVVCGDLCV SGSRPVTGSV
460 470
CSAPCSGNVA VSTGLCAPCG SGPCHPGRC
Length:479
Mass (Da):52,810
Last modified:April 5, 2011 - v1
Checksum:i943D0A730C306499
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC103674 Genomic DNA No translation available.
RefSeqiNP_001188252.1, NM_001201323.1
UniGeneiMm.347934

Genome annotation databases

EnsembliENSMUST00000023718; ENSMUSP00000023718; ENSMUSG00000067613
GeneIDi100126226
KEGGimmu:100126226
UCSCiuc007xtj.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC103674 Genomic DNA No translation available.
RefSeqiNP_001188252.1, NM_001201323.1
UniGeneiMm.347934

3D structure databases

ProteinModelPortaliE9Q1Y9
SMRiE9Q1Y9
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000023718

PTM databases

iPTMnetiE9Q1Y9
PhosphoSitePlusiE9Q1Y9

Proteomic databases

MaxQBiE9Q1Y9
PaxDbiE9Q1Y9
PeptideAtlasiE9Q1Y9
PRIDEiE9Q1Y9

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000023718; ENSMUSP00000023718; ENSMUSG00000067613
GeneIDi100126226
KEGGimmu:100126226
UCSCiuc007xtj.2 mouse

Organism-specific databases

CTDi3889
MGIiMGI:3690448 Krt83

Phylogenomic databases

eggNOGiENOG410IH1H Eukaryota
ENOG41113GZ LUCA
GeneTreeiENSGT00910000144006
InParanoidiE9Q1Y9
KOiK07605
OMAiCGFSTVG
OrthoDBiEOG091G06FG
PhylomeDBiE9Q1Y9
TreeFamiTF317854

Enzyme and pathway databases

ReactomeiR-MMU-6805567 Keratinization
R-MMU-6809371 Formation of the cornified envelope

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000067613 Expressed in 71 organ(s), highest expression level in skin of back
GenevisibleiE9Q1Y9 MM

Family and domain databases

InterProiView protein in InterPro
IPR001664 IF
IPR018039 IF_conserved
IPR039008 IF_rod_dom
IPR032444 Keratin_2_head
IPR003054 Keratin_II
PANTHERiPTHR23239 PTHR23239, 1 hit
PfamiView protein in Pfam
PF00038 Filament, 1 hit
PF16208 Keratin_2_head, 1 hit
PRINTSiPR01276 TYPE2KERATIN
SMARTiView protein in SMART
SM01391 Filament, 1 hit
PROSITEiView protein in PROSITE
PS00226 IF_ROD_1, 1 hit
PS51842 IF_ROD_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE9Q1Y9_MOUSE
AccessioniPrimary (citable) accession number: E9Q1Y9
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: November 7, 2018
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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