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Protein
Submitted name:

PDZ domain-containing 2

Gene

Pdzd2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
PDZ domain-containing 2Imported
Gene namesi
Name:Pdzd2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 15

Organism-specific databases

MGIiMGI:1922394 Pdzd2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

MaxQBiE9Q1M1
PaxDbiE9Q1M1
PeptideAtlasiE9Q1M1
PRIDEiE9Q1M1

PTM databases

iPTMnetiE9Q1M1
PhosphoSitePlusiE9Q1M1

Expressioni

Gene expression databases

BgeeiENSMUSG00000022197 Expressed in 229 organ(s), highest expression level in lung
ExpressionAtlasiE9Q1M1 baseline and differential
GenevisibleiE9Q1M1 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000074788

Structurei

3D structure databases

SMRiE9Q1M1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini94 – 160PDZInterPro annotationAdd BLAST67
Domaini334 – 419PDZInterPro annotationAdd BLAST86
Domaini588 – 674PDZInterPro annotationAdd BLAST87
Domaini731 – 801PDZInterPro annotationAdd BLAST71
Domaini2580 – 2652PDZInterPro annotationAdd BLAST73
Domaini2708 – 2793PDZInterPro annotationAdd BLAST86

Phylogenomic databases

eggNOGiKOG0708 Eukaryota
KOG3528 Eukaryota
ENOG4110362 LUCA
GeneTreeiENSGT00760000119017
InParanoidiE9Q1M1
OMAiHPYFTPR
OrthoDBiEOG091G0G6P
TreeFamiTF326303

Family and domain databases

InterProiView protein in InterPro
IPR001478 PDZ
IPR036034 PDZ_sf
PfamiView protein in Pfam
PF00595 PDZ, 5 hits
SMARTiView protein in SMART
SM00228 PDZ, 6 hits
SUPFAMiSSF50156 SSF50156, 6 hits
PROSITEiView protein in PROSITE
PS50106 PDZ, 6 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

E9Q1M1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPITQDNALL HLPLLYEWLQ NSLREGGDSP EQRLCQAAIQ KLQEYIQLNL
60 70 80 90 100
AVEENTVPPE HSPPEMEICT VYLTKQLGDT ETVGLSFGNI PVFGDYGEKR
110 120 130 140 150
RGGKKRKTHQ GPVLDVGCIW VTELRKNSPA GKSGKVRLRD EILSLNGQLM
160 170 180 190 200
VGVDVSGASY LAEQCWNGGF IYLIMLRRFK QKAHLTYNGN SGNSSEPGET
210 220 230 240 250
PTLELGDQTS KKGKRTRKFG VISRPAIIKA PEDSKSNSGC DTADDPSSEL
260 270 280 290 300
ENGTDSELGN GHAFELENGP NSLKDVAGPH LERSEADREA ELRVPKTEAP
310 320 330 340 350
LSDSNDKRRF SKTGKTNFQS SDSLAREEVG RIWKMELLKE SDGLGIQVSG
360 370 380 390 400
GRGSKRSPHA IVVTQVKEGG AAHRDGRLSL GDELLVINGH LLVGLSHEEA
410 420 430 440 450
VAILRSATGM VQLVVASKES SAEDLLKLTS KSLPDLTSSV EDISSWTDNE
460 470 480 490 500
DQEAARDDEE GTGSAAVRGT MLGSEESQDV GSSEESKGNN LESPKQGNSK
510 520 530 540 550
MKLKSRLSGG VHRLESVEEY NELMVRNGDP RIRMLEVSRD GRKHSLPQLL
560 570 580 590 600
DSTGTSQEYH IVKKSTRSLS TTHVESPWRL IRPSVISIIG LYKEKGKGLG
610 620 630 640 650
FSIAGGRDCV RGQMGIFVKT IFPNGSAAED GRLKEGDEIL DVNGIPIKGL
660 670 680 690 700
TFQEAIHTFK QIRSGLFVLT VRTKLLSPSL TPCSTPTHMS RSSSPSFNSS
710 720 730 740 750
GGAPAGGGQD EGGSASLGRK APGPKDRIVM EVTLNKEPRV GLGIGACCLA
760 770 780 790 800
LENSPPGIYI HSLAPGSVAK MESNLSRGDQ ILEVNSVNVR HAALSKVHAI
810 820 830 840 850
LSKCPPGPVR LVIGRHPNPK VSEQEMDEVI ARSTYQESKE ANSSPSLGTP
860 870 880 890 900
LKSPSLAKKD SLLSESELSQ YFVHDGQGSL SDFVVAGSED EDHPGSGYET
910 920 930 940 950
SEDGSLLTVP SAYRETGKAR ANSLVTLGSQ RGSGLLHKQV TVARQASLPG
960 970 980 990 1000
SPQVLRNPLL RQRRVRCYDS NDGSDDEDFD GEGDCVSLPG VLPGPGRPLV
1010 1020 1030 1040 1050
QDDTRFALAT SSKSIDVNKQ DERLQKPLVS KACSVPLLGS SLDSEHSIHG
1060 1070 1080 1090 1100
GTAGTPPKAA SLPGSVETPK NGPGGSRRKE MSGSRSSPKL EYRVPADTQS
1110 1120 1130 1140 1150
PRSPENGTSP PQKTENLVSR HKPVARISPH YKRSDAEEAP SETANGPCAQ
1160 1170 1180 1190 1200
DLKVQASSVK DPVAGHQPGG TAEKELRGNP TPGDSSVPTN CGPASTPCHP
1210 1220 1230 1240 1250
NTGLPTENPQ GAAPECGPHP GTGWDGSSDH PPSPGKSREV RPDSSETPAV
1260 1270 1280 1290 1300
TEQVLQPESL SQPVSPGTSE PESQGVSKMK PASQRSLSPR EKASALPDSS
1310 1320 1330 1340 1350
RTWAGPGDST PSTRRAAVPM SIGETRATAI PHPSLLGQER SRDPSGPSKA
1360 1370 1380 1390 1400
LETPGHCVPT SLKDRALLEE TASASGKLSH AGPSVPVTTD GTLSGSTESP
1410 1420 1430 1440 1450
VTDIDKFIGE APEAWLSQSP QRADCRTHQD IFESQPPGGA GGGSSHHGKT
1460 1470 1480 1490 1500
GGTGSPPPPQ WTFQPSVLDS VHPDKQLAGN KNFLNNYSRN FSSFHEDGVS
1510 1520 1530 1540 1550
EPSPSSMYGD AEDSSSDPES LVEDPRAAAR NNWPAPPSHE SSRKEGSSES
1560 1570 1580 1590 1600
EDEQIEICAP GGCPETPVPA QAPAQAAGGA VPSVQQTVRE PVGDACEKAC
1610 1620 1630 1640 1650
FMTGASNTCI PGSSQPFSFL DVSSLEHETW AGVQTSRSHM PGCAEETLAV
1660 1670 1680 1690 1700
SSTGSVVGDS QPSQTTRPCG NPPFVLRNPD MVNGLGQDLL DEGTPDKGAD
1710 1720 1730 1740 1750
ASHVMSSVYA LGAEGPKNGE AVLANLHIAK GGNLDGLLQK PKTTSRRPIM
1760 1770 1780 1790 1800
TWFKDINKDS QGAHLQSKSE KEQPSMLAMS PGSKGNTVNP SHRKGMAVPK
1810 1820 1830 1840 1850
SPPPRQKSQE NKDLSPKSPV ETLSNCQKPK GSPKLKRLNS KSKASPEAPV
1860 1870 1880 1890 1900
ASPAKGGRTD HRKSLPSPQA AHKMLSKAVS HRLHIADQEE PKNTAGDTSK
1910 1920 1930 1940 1950
PPQCVPESKP PLAASGSLRT SASDTSIRTI TSPLTSPKPL PEQGANNRFH
1960 1970 1980 1990 2000
MAVYLESDTS CPATSRPPRY GPEGKVPHAN SGSVSPSASR TNIALAGVRQ
2010 2020 2030 2040 2050
SKQFTHSRVD LVLTEAAQPQ GISEKGTEKM ASDPLERTNQ LKIIEISSER
2060 2070 2080 2090 2100
MPKNACGDKP PGSDRKGGFL TQSNCQEKSS VRLRQSAESS PKQPHFPPSQ
2110 2120 2130 2140 2150
ASQGEQEMRW SYSMARLASS SPSAPQLPSK MPDYSQGKSS QMPASVGVPK
2160 2170 2180 2190 2200
NGVPVGLAGE EPPYFTPRPA TRTYSMPAQF SSHFGREGLS PPSPSHSPQD
2210 2220 2230 2240 2250
PQVTAMSGSL SEKSAKGVTN EQGVYSVKPL LETLRNPPPV DVGDVSAVPE
2260 2270 2280 2290 2300
ASGLIPDKLK VTRRHYYCEQ SWPHESTSFF SVKQRIKSFE NLANSDRPAA
2310 2320 2330 2340 2350
KSATSPFLSV SSKPPVNRRS SGSITSGRPS DGTARSLRRS LSSCSENQSE
2360 2370 2380 2390 2400
ASSLLPQMTK SPSSVTLTVS RQNPPETNNK GHSPDPKKSL VPVGIPISTG
2410 2420 2430 2440 2450
SPASPIKRNK SSVRHAQPSP VSRSKLQELR ALSMPDLDKL CSGEDYSASP
2460 2470 2480 2490 2500
GAVLFRTQLE ITPRRSQGSP ATSPASSPAR GHADVNGSAF LSCPVNGGNR
2510 2520 2530 2540 2550
VYPKGNSSPT VPTGSREWGE SLRAMPSGKS WSVNLDQLLA SVGYQQRLQA
2560 2570 2580 2590 2600
VLSLVGSKSP ILPLIQEAKA QSENKEDICF IVLNKKEGSG LGFSVAGGAD
2610 2620 2630 2640 2650
VEPESVLVHR VFSQGVASQE GTVSQGDFLL SVNGTSLAGL SHSEVTKVLH
2660 2670 2680 2690 2700
QAELHKHVLM IIKKGNDQPR PSFRQEPPSA NGKAPFPRRT LPLEPGAGRN
2710 2720 2730 2740 2750
GAAHDALCVE VLKTSAGLGL SLDGGKSSIA GDGPLVIKRV YQGGAAEQAG
2760 2770 2780 2790
TIEAGDEILA INGKPLVGLV HFDAWNIMKS VPEGPVQLVI RKHRDS
Length:2,796
Mass (Da):296,726
Last modified:April 5, 2011 - v1
Checksum:i6C572A52CC451A69
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A087WRL4A0A087WRL4_MOUSE
PDZ domain-containing 2
Pdzd2
363Annotation score:
A0A087WS85A0A087WS85_MOUSE
PDZ domain-containing 2
Pdzd2
36Annotation score:
A0A087WQ09A0A087WQ09_MOUSE
PDZ domain-containing 2
Pdzd2
49Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC133282 Genomic DNA No translation available.
AC135292 Genomic DNA No translation available.
AC150660 Genomic DNA No translation available.
RefSeqiNP_001074533.1, NM_001081064.1
XP_006520222.1, XM_006520159.3
XP_006520223.1, XM_006520160.3
XP_006520224.1, XM_006520161.3
XP_006520225.1, XM_006520162.2
XP_006520226.1, XM_006520163.3
XP_006520227.1, XM_006520164.2
UniGeneiMm.423205

Genome annotation databases

EnsembliENSMUST00000075317; ENSMUSP00000074788; ENSMUSG00000022197
GeneIDi68070
KEGGimmu:68070
UCSCiuc007vhq.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC133282 Genomic DNA No translation available.
AC135292 Genomic DNA No translation available.
AC150660 Genomic DNA No translation available.
RefSeqiNP_001074533.1, NM_001081064.1
XP_006520222.1, XM_006520159.3
XP_006520223.1, XM_006520160.3
XP_006520224.1, XM_006520161.3
XP_006520225.1, XM_006520162.2
XP_006520226.1, XM_006520163.3
XP_006520227.1, XM_006520164.2
UniGeneiMm.423205

3D structure databases

SMRiE9Q1M1
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000074788

PTM databases

iPTMnetiE9Q1M1
PhosphoSitePlusiE9Q1M1

Proteomic databases

MaxQBiE9Q1M1
PaxDbiE9Q1M1
PeptideAtlasiE9Q1M1
PRIDEiE9Q1M1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000075317; ENSMUSP00000074788; ENSMUSG00000022197
GeneIDi68070
KEGGimmu:68070
UCSCiuc007vhq.1 mouse

Organism-specific databases

CTDi23037
MGIiMGI:1922394 Pdzd2

Phylogenomic databases

eggNOGiKOG0708 Eukaryota
KOG3528 Eukaryota
ENOG4110362 LUCA
GeneTreeiENSGT00760000119017
InParanoidiE9Q1M1
OMAiHPYFTPR
OrthoDBiEOG091G0G6P
TreeFamiTF326303

Miscellaneous databases

ChiTaRSiPdzd2 mouse
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000022197 Expressed in 229 organ(s), highest expression level in lung
ExpressionAtlasiE9Q1M1 baseline and differential
GenevisibleiE9Q1M1 MM

Family and domain databases

InterProiView protein in InterPro
IPR001478 PDZ
IPR036034 PDZ_sf
PfamiView protein in Pfam
PF00595 PDZ, 5 hits
SMARTiView protein in SMART
SM00228 PDZ, 6 hits
SUPFAMiSSF50156 SSF50156, 6 hits
PROSITEiView protein in PROSITE
PS50106 PDZ, 6 hits
ProtoNetiSearch...

Entry informationi

Entry nameiE9Q1M1_MOUSE
AccessioniPrimary (citable) accession number: E9Q1M1
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: November 7, 2018
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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