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Protein

Protein mono-ADP-ribosyltransferase PARP4

Gene

Parp4

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Mono-ADP-ribosyltransferase that mediates mono-ADP-ribosylation of target proteins.By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGlycosyltransferase, Ribonucleoprotein, Transferase
LigandNAD

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-197264 Nicotinamide salvaging

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein mono-ADP-ribosyltransferase PARP4Curated (EC:2.4.2.-By similarity)
Alternative name(s):
ADP-ribosyltransferase diphtheria toxin-like 4By similarity
Short name:
ARTD4By similarity
Poly [ADP-ribose] polymerase 4By similarity
Short name:
PARP-4By similarity
Vault poly(ADP-ribose) polymerase1 Publication
Short name:
VPARP1 Publication
Short name:
mVparp1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Parp4Imported
Synonyms:Kiaa01771 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 14

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2685589 Parp4

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

No visible phenotype (PubMed:15169895). Mice are viable and fertile for up to five generations, with no apparent changes in telomerase activity or telomere length (PubMed:15169895).1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004461711 – 1969Protein mono-ADP-ribosyltransferase PARP4Add BLAST1969

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1229PhosphoserineBy similarity1

Keywords - PTMi

Methylation, Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
E9PYK3

MaxQB - The MaxQuant DataBase

More...
MaxQBi
E9PYK3

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
E9PYK3

PeptideAtlas

More...
PeptideAtlasi
E9PYK3

PRoteomics IDEntifications database

More...
PRIDEi
E9PYK3

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
E9PYK3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
E9PYK3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000054509 Expressed in 183 organ(s), highest expression level in bone marrow macrophage

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
E9PYK3 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the vault ribonucleoprotein particle, at least composed of MVP, PARP4 and one or more vault RNAs (vRNAs). Interacts with TEP1.By similarity

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000124258

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
E9PYK3

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 94BRCTPROSITE-ProRule annotationAdd BLAST94
Domaini235 – 363PARP alpha-helicalPROSITE-ProRule annotationAdd BLAST129
Domaini362 – 566PARP catalyticPROSITE-ProRule annotationAdd BLAST205
Domaini600 – 728VITPROSITE-ProRule annotationAdd BLAST129
Domaini869 – 1039VWFAPROSITE-ProRule annotationAdd BLAST171
Domaini1443 – 1541FH1Sequence analysisAdd BLAST99

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1808 – 1969Interaction with the major vault proteinBy similarityAdd BLAST162

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi19 – 25Nuclear localization signalSequence analysis7
Motifi1230 – 1242Nuclear localization signalSequence analysisAdd BLAST13

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1037 Eukaryota
ENOG410XP18 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00530000063006

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000139369

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG053515

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
E9PYK3

KEGG Orthology (KO)

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KOi
K10798

Identification of Orthologs from Complete Genome Data

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OMAi
FHPHENT

Database of Orthologous Groups

More...
OrthoDBi
955432at2759

TreeFam database of animal gene trees

More...
TreeFami
TF329720

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00027 BRCT, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.50.10190, 1 hit
3.40.50.410, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001357 BRCT_dom
IPR036420 BRCT_dom_sf
IPR009408 Formin_homology_1
IPR031273 PARP4
IPR012317 Poly(ADP-ribose)pol_cat_dom
IPR004102 Poly(ADP-ribose)pol_reg_dom
IPR036616 Poly(ADP-ribose)pol_reg_dom_sf
IPR013694 VIT
IPR002035 VWF_A
IPR036465 vWFA_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR10338:SF127 PTHR10338:SF127, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF16589 BRCT_2, 1 hit
PF06346 Drf_FH1, 1 hit
PF00644 PARP, 1 hit
PF08487 VIT, 1 hit
PF13768 VWA_3, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00292 BRCT, 1 hit
SM00609 VIT, 1 hit
SM00327 VWA, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47587 SSF47587, 1 hit
SSF52113 SSF52113, 1 hit
SSF53300 SSF53300, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50172 BRCT, 1 hit
PS51060 PARP_ALPHA_HD, 1 hit
PS51059 PARP_CATALYTIC, 1 hit
PS51468 VIT, 1 hit
PS50234 VWFA, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

E9PYK3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTLGIFANCI FCLKVKYLPR QQKKKLQTDI KENGGKFSFL LNPQCTHVIV
60 70 80 90 100
DSADVLSRCH LNSIQKNDVQ IANPAFIQDS VRQRRLLDVR NYDPLSPAPA
110 120 130 140 150
APPAERSRSE VQSEYLPSDN TPEKENTEVT EVSAENVEIP PFLQDFEVVK
160 170 180 190 200
YNILEKVGGP ETVVVELQSS QDPESCPFVI TAHFLLADQK TRRESTGKQT
210 220 230 240 250
SEGAIEYYES YVEDLKRQGF LLQEHFTAEA TQLASEKLQA LLLEEVISSG
260 270 280 290 300
ALSQEVSDLL EVIWTEALGH LENTLLKPVN SMSLNDVSKA EGILLLVKTA
310 320 330 340 350
LKNGDSPGQL QKTMAEFYRL LPHRHPASEE VNLRLLAQKE DLCQLVRDMV
360 370 380 390 400
NVCETNLSKP NPPSLAKYRA LRCKIEHVDQ NTEEFSRVRK EVLQNNRSEQ
410 420 430 440 450
PVDILQIFRV GRVNEATEFL SKLGNVRLLF HGSPVRNILG ILSRGLLLPK
460 470 480 490 500
VAEDRGVQRT DVGNLGSGIY FSDSLSTSIK YAHAGETDGS RLLVVCDVAL
510 520 530 540 550
GKCVNLFKKD FSLTEAPPGY DSVHGVSETT SVPTDFQDDE FVVYKTNQVK
560 570 580 590 600
MKYIVKFCTP GDQIKEFHPH ENTEVEEQRA EPSSVPEAGD FQLPDIKPFT
610 620 630 640 650
NIKAGLQDAS ANPVPLDSVH IKGRVIDFVA QVIVFQTYTN QSHVPIEAKY
660 670 680 690 700
IFPLDDKAAV CGFEAFINGK HIVGEIKEKE EARQEYREAV SQGHGAYLMD
710 720 730 740 750
QDTPDVFTVS VGNLPPRAKV LIKITYITEL SIQSPVAIFF IPGTVAPWQQ
760 770 780 790 800
DKALNENLQD TVETIRIKEI GAEQSFSLAM SIEMPYMIEF ISSDTHELRQ
810 820 830 840 850
KSTDCKAVVS TVEGSSLDSG GFSLHIGLRD AYLPRMWVEK HPEKESEACM
860 870 880 890 900
LVFQPELADV LPDLRGKNEV IICLDCSSSM EGVTFTQAKQ VALYALSLLG
910 920 930 940 950
EEQKVNIMQF GTGYKELFSY PKCITDSKMA TEFIMSAAPS MGNTDFWKVL
960 970 980 990 1000
RYLSLLYPSE GFRNILLISD GHLQSESLTL QLVKRNIQHT RVFTCAVGST
1010 1020 1030 1040 1050
ANRHILRTLS QCGAGVFEYF NSKSKHSWKK QIEAQMTRIR SPSCHSVSVK
1060 1070 1080 1090 1100
WQQLSRDAPE PLQAPAWVPS LFHNDRLLVY GFIPHCTQAT LQAFIQEKEF
1110 1120 1130 1140 1150
CTMVSTTELQ KTTGTMIHKL AARALIRDYE DGILHDDETN HEMKKNIMKS
1160 1170 1180 1190 1200
LIIELSKENS LITQFTSFVA VEKRDVNEIP FANVPNISEL VAKEDVDFLP
1210 1220 1230 1240 1250
YVSWQEKQPE ASISQTEIDS SRLKHNKLSD GHGVLQPVSV SSEVNEKPSL
1260 1270 1280 1290 1300
LLAAKKRKIK TIKKCSLDIS EDFEDRTAVA QSPATAQSLN FHLPLSVRPQ
1310 1320 1330 1340 1350
LKAVEQQLHG NRLEPKQRGG FRKLLMAKKC RNVPDSLVSS APAVTAEFSY
1360 1370 1380 1390 1400
LSACSSSSAF LSPLCDIPSS LPPHPLGGTH PPPPLPLPDG THLPSPLFGS
1410 1420 1430 1440 1450
THPPPPLFGG TLIPPPSSLF GGTHLPPPPP LPGGTHIPPP PPIPGGTLIP
1460 1470 1480 1490 1500
PSSSLFGGTH LPPPPLLSAG THIPPPPLLS AGTHLPPPPL LPAGTHIPPP
1510 1520 1530 1540 1550
PPITGSTHPP PPSSLFGGTH LPPPPPLPGG THIPPPPPIP GGTLIPSPSS
1560 1570 1580 1590 1600
LFGGTHLPPP PLLPAGTHIP PPPPITGSTH PPPPSSLFGG THLPPPPPAG
1610 1620 1630 1640 1650
TQFSLSPIGF IPPKLGPPKL SHSHKLVGDT NIHDSEPPLL GFKDLCSRDM
1660 1670 1680 1690 1700
GFSCGTAFSG SFASSKDFDP GKFSQGPNNI SFSPKAPEMG VLHQSPFCSP
1710 1720 1730 1740 1750
PKPPSAPPLV TNVLCSEAPQ SYFLNLQSAA VHQSPNNRVS EIIMESVESS
1760 1770 1780 1790 1800
LPSDYSSRDA SSYLALEGAE DSLLGGSSFE TDTDEAAAFI ANDLLTSIET
1810 1820 1830 1840 1850
SSDEECAFCD EDQESPVPWA SLFALQTENG FWKLTPELGL ILNLNVNALL
1860 1870 1880 1890 1900
TSLEEKGIRS LGTKGRERLL DLIATLLVLQ FLYTKLEQEG MVAKSLIKMD
1910 1920 1930 1940 1950
DAFISRNIPW AFENIKKARE WARKTEGQYP SICQRLELGK DWESATKQLL
1960
GIQPQANTSL HRILYYSQG
Length:1,969
Mass (Da):216,133
Last modified:April 5, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB1EDC5481653F93A
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAD32185 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti611A → T in BAD32185 (PubMed:15368895).Curated1
Sequence conflicti1634D → N in AAH25847 (PubMed:15489334).Curated1
Sequence conflicti1691V → A in AAH25847 (PubMed:15489334).Curated1
Sequence conflicti1754D → H in BAC35611 (PubMed:16141072).Curated1
Sequence conflicti1918A → T in AAH25847 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC154731 Genomic DNA No translation available.
AC154837 Genomic DNA No translation available.
AK172907 mRNA Translation: BAD32185.1 Different initiation.
BC025847 mRNA Translation: AAH25847.1
BC046397 mRNA Translation: AAH46397.1
AK053992 mRNA Translation: BAC35611.1

NCBI Reference Sequences

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RefSeqi
NP_001139450.2, NM_001145978.2

UniGene gene-oriented nucleotide sequence clusters

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UniGenei
Mm.379357

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000161553; ENSMUSP00000124258; ENSMUSG00000054509

Database of genes from NCBI RefSeq genomes

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GeneIDi
328417

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:328417

UCSC genome browser

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UCSCi
uc007ucd.2 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC154731 Genomic DNA No translation available.
AC154837 Genomic DNA No translation available.
AK172907 mRNA Translation: BAD32185.1 Different initiation.
BC025847 mRNA Translation: AAH25847.1
BC046397 mRNA Translation: AAH46397.1
AK053992 mRNA Translation: BAC35611.1
RefSeqiNP_001139450.2, NM_001145978.2
UniGeneiMm.379357

3D structure databases

SMRiE9PYK3
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000124258

PTM databases

iPTMnetiE9PYK3
PhosphoSitePlusiE9PYK3

Proteomic databases

jPOSTiE9PYK3
MaxQBiE9PYK3
PaxDbiE9PYK3
PeptideAtlasiE9PYK3
PRIDEiE9PYK3

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000161553; ENSMUSP00000124258; ENSMUSG00000054509
GeneIDi328417
KEGGimmu:328417
UCSCiuc007ucd.2 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
143
MGIiMGI:2685589 Parp4

Rodent Unidentified Gene-Encoded large proteins database

More...
Rougei
Search...

Phylogenomic databases

eggNOGiKOG1037 Eukaryota
ENOG410XP18 LUCA
GeneTreeiENSGT00530000063006
HOGENOMiHOG000139369
HOVERGENiHBG053515
InParanoidiE9PYK3
KOiK10798
OMAiFHPHENT
OrthoDBi955432at2759
TreeFamiTF329720

Enzyme and pathway databases

ReactomeiR-MMU-197264 Nicotinamide salvaging

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Parp4 mouse

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000054509 Expressed in 183 organ(s), highest expression level in bone marrow macrophage
GenevisibleiE9PYK3 MM

Family and domain databases

CDDicd00027 BRCT, 1 hit
Gene3Di3.40.50.10190, 1 hit
3.40.50.410, 1 hit
InterProiView protein in InterPro
IPR001357 BRCT_dom
IPR036420 BRCT_dom_sf
IPR009408 Formin_homology_1
IPR031273 PARP4
IPR012317 Poly(ADP-ribose)pol_cat_dom
IPR004102 Poly(ADP-ribose)pol_reg_dom
IPR036616 Poly(ADP-ribose)pol_reg_dom_sf
IPR013694 VIT
IPR002035 VWF_A
IPR036465 vWFA_dom_sf
PANTHERiPTHR10338:SF127 PTHR10338:SF127, 1 hit
PfamiView protein in Pfam
PF16589 BRCT_2, 1 hit
PF06346 Drf_FH1, 1 hit
PF00644 PARP, 1 hit
PF08487 VIT, 1 hit
PF13768 VWA_3, 1 hit
SMARTiView protein in SMART
SM00292 BRCT, 1 hit
SM00609 VIT, 1 hit
SM00327 VWA, 1 hit
SUPFAMiSSF47587 SSF47587, 1 hit
SSF52113 SSF52113, 1 hit
SSF53300 SSF53300, 1 hit
PROSITEiView protein in PROSITE
PS50172 BRCT, 1 hit
PS51060 PARP_ALPHA_HD, 1 hit
PS51059 PARP_CATALYTIC, 1 hit
PS51468 VIT, 1 hit
PS50234 VWFA, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPARP4_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E9PYK3
Secondary accession number(s): Q6A0B1
, Q80UW6, Q8BW82, Q8R3A5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 16, 2019
Last sequence update: April 5, 2011
Last modified: January 16, 2019
This is version 64 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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