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Protein

Olfactory receptor

Gene

Olfr592

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer
Biological processOlfactionUniRule annotationSAAS annotation, Sensory transduction

Enzyme and pathway databases

ReactomeiR-MMU-381753 Olfactory Signaling Pathway

Names & Taxonomyi

Protein namesi
Recommended name:
Olfactory receptorUniRule annotation
Gene namesi
Name:Olfr592Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:3030426 Olfr592

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei26 – 51HelicalUniRule annotationAdd BLAST26
Transmembranei63 – 81HelicalUniRule annotationAdd BLAST19
Transmembranei101 – 123HelicalUniRule annotationAdd BLAST23
Transmembranei143 – 167HelicalUniRule annotationAdd BLAST25
Transmembranei199 – 223HelicalUniRule annotationAdd BLAST25
Transmembranei243 – 262HelicalUniRule annotationAdd BLAST20
Transmembranei274 – 294HelicalUniRule annotationAdd BLAST21

Keywords - Cellular componenti

Cell membraneUniRule annotationSAAS annotation, Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000073956 Expressed in 2 organ(s), highest expression level in spleen

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000095808

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini44 – 294G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST251

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG410J9ST Eukaryota
ENOG411193D LUCA
GeneTreeiENSGT00910000144038
KOiK04257
OMAiVHMWISL
OrthoDBiEOG091G0AZH
TreeFamiTF343679

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR000725 Olfact_rcpt
PfamiView protein in Pfam
PF13853 7tm_4, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PR00245 OLFACTORYR
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

E9PYB3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTIHNNRSVS HPDTFFLIGI PGLEEIHAWI SLPFCCIYLV ALMGNTMILV
60 70 80 90 100
VIKTERSLRE PMFYFLAILS SVDLALSTTS VPRMLGIFWF DAHEINFGGC
110 120 130 140 150
VAQMFLIHAF TGMEAEVLMA MAFDRYVAIC APLHYTTILT SRVLMGISIC
160 170 180 190 200
VVIRPALFIC PMVYLIYRLP FCQAHVIAHS YCEHMGIAKL SCGDIHINAV
210 220 230 240 250
YGLFVVSLFL LNLVLIGISY GYILRAVFRL PSQDARLKAL STCGSHVAVL
260 270 280 290 300
CVFYIPSVFS FLTHRFGHNI PHYIHILVAN LYLVIPPSLN PIIYSVRTKQ
310
IREHVLHIFT KR
Length:312
Mass (Da):35,239
Last modified:April 5, 2011 - v1
Checksum:i636950B22D38AAC0
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2I3BPE8A0A2I3BPE8_MOUSE
Olfactory receptor
Olfr592
323Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC109166 Genomic DNA No translation available.
RefSeqiNP_997439.2, NM_207556.2
UniGeneiMm.377359

Genome annotation databases

EnsembliENSMUST00000098207; ENSMUSP00000095808; ENSMUSG00000073956
ENSMUST00000106893; ENSMUSP00000102506; ENSMUSG00000073956
GeneIDi404317
KEGGimmu:404317
UCSCiuc009ith.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC109166 Genomic DNA No translation available.
RefSeqiNP_997439.2, NM_207556.2
UniGeneiMm.377359

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000095808

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000098207; ENSMUSP00000095808; ENSMUSG00000073956
ENSMUST00000106893; ENSMUSP00000102506; ENSMUSG00000073956
GeneIDi404317
KEGGimmu:404317
UCSCiuc009ith.1 mouse

Organism-specific databases

CTDi404317
MGIiMGI:3030426 Olfr592

Phylogenomic databases

eggNOGiENOG410J9ST Eukaryota
ENOG411193D LUCA
GeneTreeiENSGT00910000144038
KOiK04257
OMAiVHMWISL
OrthoDBiEOG091G0AZH
TreeFamiTF343679

Enzyme and pathway databases

ReactomeiR-MMU-381753 Olfactory Signaling Pathway

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000073956 Expressed in 2 organ(s), highest expression level in spleen

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR000725 Olfact_rcpt
PfamiView protein in Pfam
PF13853 7tm_4, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PR00245 OLFACTORYR
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE9PYB3_MOUSE
AccessioniPrimary (citable) accession number: E9PYB3
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: November 7, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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