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Protein
Submitted name:

ArfGAP with dual PH domains 1

Gene

Adap1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
ArfGAP with dual PH domains 1Imported
Gene namesi
Name:Adap1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 5

Organism-specific databases

MGIiMGI:2442201 Adap1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

MaxQBiE9PY16
PaxDbiE9PY16
PeptideAtlasiE9PY16
PRIDEiE9PY16

Expressioni

Gene expression databases

BgeeiENSMUSG00000056413 Expressed in 168 organ(s), highest expression level in intestine
GenevisibleiE9PY16 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000106489

Structurei

3D structure databases

ProteinModelPortaliE9PY16
SMRiE9PY16
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 126Arf-GAPInterPro annotationAdd BLAST121
Domaini129 – 230PHInterPro annotationAdd BLAST102
Domaini252 – 356PHInterPro annotationAdd BLAST105

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0703 Eukaryota
COG5347 LUCA
GeneTreeiENSGT00900000140892
InParanoidiE9PY16
OMAiYEERVPP
OrthoDBiEOG091G0789
TreeFamiTF324540

Family and domain databases

CDDicd13252 PH1_ADAP, 1 hit
cd01251 PH2_ADAP, 1 hit
Gene3Di2.30.29.30, 2 hits
3.30.40.160, 1 hit
InterProiView protein in InterPro
IPR037278 ARFGAP/RecO
IPR001164 ArfGAP_dom
IPR038508 ArfGAP_dom_sf
IPR011993 PH-like_dom_sf
IPR037849 PH1_ADAP
IPR037851 PH2_ADAP
IPR001849 PH_domain
PfamiView protein in Pfam
PF01412 ArfGap, 1 hit
PF00169 PH, 2 hits
PRINTSiPR00405 REVINTRACTNG
SMARTiView protein in SMART
SM00105 ArfGap, 1 hit
SM00233 PH, 2 hits
SUPFAMiSSF57863 SSF57863, 1 hit
PROSITEiView protein in PROSITE
PS50115 ARFGAP, 1 hit
PS50003 PH_DOMAIN, 2 hits

Sequencei

Sequence statusi: Complete.

E9PY16-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAGERRRALL ELLTRPGNTR CADCGAPDPD WASYTLGVFI CLSCSGIHRN
60 70 80 90 100
IPQVSKVKSV RLDAWDEAQV EFMASHGNEA ARATFESKVP PFYYRPTFSD
110 120 130 140 150
CQLLREQWIR AKYERQEFVH VEKQEPYSTG YREGLLWKRG RDNGQFLSRK
160 170 180 190 200
FVLTEREGAL KYFNKNDAKE PKAVMKIEHL NATFQPAKMG HPHGLQVTYL
210 220 230 240 250
KDNSTRNIFI YHEDGKEIVD WFNALRAARF HYLQVAFPGA SDADLVPKLS
260 270 280 290 300
RNYLKEGYME KTGPKQTEGF RKRWFTMDDR RLMYFKDPLD AFARGEVFIG
310 320 330 340 350
SKESGYTVLE GLPLSTQGHH WPHGITIVTP DRKFLFTCET ESDQREWIAA
360 370
FQKVVDRPML PQEYAVEAHF KHKP
Length:374
Mass (Da):43,370
Last modified:April 5, 2011 - v1
Checksum:i9D00C6516BFF7F52
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC125065 Genomic DNA No translation available.
AC161058 Genomic DNA No translation available.
RefSeqiNP_766311.2, NM_172723.4
UniGeneiMm.297819

Genome annotation databases

EnsembliENSMUST00000110865; ENSMUSP00000106489; ENSMUSG00000056413
GeneIDi231821
KEGGimmu:231821
UCSCiuc009agi.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC125065 Genomic DNA No translation available.
AC161058 Genomic DNA No translation available.
RefSeqiNP_766311.2, NM_172723.4
UniGeneiMm.297819

3D structure databases

ProteinModelPortaliE9PY16
SMRiE9PY16
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000106489

Proteomic databases

MaxQBiE9PY16
PaxDbiE9PY16
PeptideAtlasiE9PY16
PRIDEiE9PY16

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000110865; ENSMUSP00000106489; ENSMUSG00000056413
GeneIDi231821
KEGGimmu:231821
UCSCiuc009agi.1 mouse

Organism-specific databases

CTDi11033
MGIiMGI:2442201 Adap1

Phylogenomic databases

eggNOGiKOG0703 Eukaryota
COG5347 LUCA
GeneTreeiENSGT00900000140892
InParanoidiE9PY16
OMAiYEERVPP
OrthoDBiEOG091G0789
TreeFamiTF324540

Miscellaneous databases

ChiTaRSiAdap1 mouse
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000056413 Expressed in 168 organ(s), highest expression level in intestine
GenevisibleiE9PY16 MM

Family and domain databases

CDDicd13252 PH1_ADAP, 1 hit
cd01251 PH2_ADAP, 1 hit
Gene3Di2.30.29.30, 2 hits
3.30.40.160, 1 hit
InterProiView protein in InterPro
IPR037278 ARFGAP/RecO
IPR001164 ArfGAP_dom
IPR038508 ArfGAP_dom_sf
IPR011993 PH-like_dom_sf
IPR037849 PH1_ADAP
IPR037851 PH2_ADAP
IPR001849 PH_domain
PfamiView protein in Pfam
PF01412 ArfGap, 1 hit
PF00169 PH, 2 hits
PRINTSiPR00405 REVINTRACTNG
SMARTiView protein in SMART
SM00105 ArfGap, 1 hit
SM00233 PH, 2 hits
SUPFAMiSSF57863 SSF57863, 1 hit
PROSITEiView protein in PROSITE
PS50115 ARFGAP, 1 hit
PS50003 PH_DOMAIN, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiE9PY16_MOUSE
AccessioniPrimary (citable) accession number: E9PY16
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: November 7, 2018
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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