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Protein
Submitted name:

Metastasis-associated in colon cancer 1

Gene

Macc1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Metastasis-associated in colon cancer 1Imported
Gene namesi
Name:Macc1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 12

Organism-specific databases

MGIiMGI:2685113 Macc1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000041886 Expressed in 108 organ(s), highest expression level in epithelium of stomach
GenevisibleiE9PXX8 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000042955

Structurei

3D structure databases

ProteinModelPortaliE9PXX8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini212 – 349ZU5InterPro annotationAdd BLAST138
Domaini548 – 618SH3InterPro annotationAdd BLAST71

Keywords - Domaini

SH3 domainPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG410IHUQ Eukaryota
ENOG410YRKQ LUCA
GeneTreeiENSGT00390000013151
InParanoidiE9PXX8
OMAiVCGHSYM
OrthoDBiEOG091G012M
TreeFamiTF105572

Family and domain databases

InterProiView protein in InterPro
IPR001452 SH3_domain
IPR000906 ZU5_dom
PfamiView protein in Pfam
PF07653 SH3_2, 1 hit
PF00791 ZU5, 1 hit
PROSITEiView protein in PROSITE
PS50002 SH3, 1 hit
PS51145 ZU5, 1 hit

Sequencei

Sequence statusi: Complete.

E9PXX8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLISERAYCW PREIGRSRSE GNLIDMEASK RSKNQNITAR QGLGLPHNWP
60 70 80 90 100
DAPTLHRDSD AKATNPFWKE LSASNPFLED ITQLRNNKKR DNMSILKEDP
110 120 130 140 150
FLFLRQIETE NSFDSSGDEL DMDQGFKSSS SRKSGRSKSV SELLDVLGDR
160 170 180 190 200
THTHQSIHSS DQILIQDLEW LQNDREAYKM AWLSQRQLAR SCLDLNTINQ
210 220 230 240 250
SPGWAQTQIA ETIAVCKLNH QGGSVQLPDS DITIHIPQGH IAVGEFQEVS
260 270 280 290 300
LRAFLDPPPK LNHDLSCTVS PLLEIRLSNL NTMEAILLEM KTGAEVKTDP
310 320 330 340 350
LSQVMTKMVC LYSLDREGPF QALNTCYIYK DTIQAKLLDL SHVMYIVIAV
360 370 380 390 400
QATIIHPPAA TIWDYIHKTT SIGIYGPKYL HPSFTAVFTV CGHNYVPGKF
410 420 430 440 450
TVSDIRKGGK NTSPVVFHLW GKHSFSLDKP KDLIISAFSC DPDFEVKEEG
460 470 480 490 500
ERKVIAQRQL EAGVVVHQQV FFSSIDHREM HLFVFRVQVK TPNEKPVTQF
510 520 530 540 550
FVTSPDPSPN LKRFSYLPGF FQKREDKRVP LLSTGLVKYP TFQDKKLNFT
560 570 580 590 600
NYGVALKTVL RQNKIDYLLE YLKGDTIALL GEGTVRAIGQ SKVKEWYVGV
610 620 630 640 650
LRGKIGLVHC KNVKVISKEQ VMSMSDGILT TKNLLEQIAL PFKSLTYIYS
660 670 680 690 700
VVLTLVSEKV HDWKVLANVL GYSHLAQEDF NRIQADKEPE RVSYVVKKLK
710 720 730 740 750
EDCHEDRNTR KFLYELIVAL LKMDCQELVA HLIQEAVILT SAVKLGRSWR
760 770 780 790 800
ELAEKSAGLT KHQMQAYEIP HRGKSGDVSA EMMWKPAYDF LYAWSFHYGN
810 820 830 840 850
SYRDVLQDLQ SALDRMKNPV TKRWRDLTGT LILINSLEIL RVTAFSTSQE

I
Length:851
Mass (Da):96,836
Last modified:April 5, 2011 - v1
Checksum:iE87267AB1249BD2F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC132596 Genomic DNA No translation available.
AC138307 Genomic DNA No translation available.
RefSeqiNP_001156608.1, NM_001163136.1
XP_006515925.1, XM_006515862.2
XP_006515926.1, XM_006515863.3
UniGeneiMm.31376

Genome annotation databases

EnsembliENSMUST00000048880; ENSMUSP00000042955; ENSMUSG00000041886
ENSMUST00000221866; ENSMUSP00000152883; ENSMUSG00000041886
ENSMUST00000221917; ENSMUSP00000152808; ENSMUSG00000041886
ENSMUST00000222058; ENSMUSP00000152123; ENSMUSG00000041886
ENSMUST00000222784; ENSMUSP00000152677; ENSMUSG00000041886
GeneIDi238455
KEGGimmu:238455
UCSCiuc007pin.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC132596 Genomic DNA No translation available.
AC138307 Genomic DNA No translation available.
RefSeqiNP_001156608.1, NM_001163136.1
XP_006515925.1, XM_006515862.2
XP_006515926.1, XM_006515863.3
UniGeneiMm.31376

3D structure databases

ProteinModelPortaliE9PXX8
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000042955

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000048880; ENSMUSP00000042955; ENSMUSG00000041886
ENSMUST00000221866; ENSMUSP00000152883; ENSMUSG00000041886
ENSMUST00000221917; ENSMUSP00000152808; ENSMUSG00000041886
ENSMUST00000222058; ENSMUSP00000152123; ENSMUSG00000041886
ENSMUST00000222784; ENSMUSP00000152677; ENSMUSG00000041886
GeneIDi238455
KEGGimmu:238455
UCSCiuc007pin.2 mouse

Organism-specific databases

CTDi346389
MGIiMGI:2685113 Macc1

Phylogenomic databases

eggNOGiENOG410IHUQ Eukaryota
ENOG410YRKQ LUCA
GeneTreeiENSGT00390000013151
InParanoidiE9PXX8
OMAiVCGHSYM
OrthoDBiEOG091G012M
TreeFamiTF105572

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000041886 Expressed in 108 organ(s), highest expression level in epithelium of stomach
GenevisibleiE9PXX8 MM

Family and domain databases

InterProiView protein in InterPro
IPR001452 SH3_domain
IPR000906 ZU5_dom
PfamiView protein in Pfam
PF07653 SH3_2, 1 hit
PF00791 ZU5, 1 hit
PROSITEiView protein in PROSITE
PS50002 SH3, 1 hit
PS51145 ZU5, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE9PXX8_MOUSE
AccessioniPrimary (citable) accession number: E9PXX8
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: November 7, 2018
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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