Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Protein FAM170B

Gene

Fam170b

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Plays a role in fertilization through the acrosome reaction.1 Publication

GO - Biological processi

  • positive regulation of acrosome reaction Source: UniProtKB
  • regulation of fertilization Source: UniProtKB

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FAM170BCurated
Alternative name(s):
Acrosome-related protein1 Publication
Gene namesi
Name:Fam170bImported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 14

Organism-specific databases

MGIiMGI:2145650 Fam170b

Subcellular locationi

Keywords - Cellular componenti

Cytoplasmic vesicle, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004354741 – 378Protein FAM170BAdd BLAST378

Proteomic databases

PaxDbiE9PXT9
PRIDEiE9PXT9

PTM databases

PhosphoSitePlusiE9PXT9

Expressioni

Tissue specificityi

Exclusively expressed in adult testis (at protein level). Expression first started at postnatal week 3 in round spermatids, elongated spermatids and mature sperm.1 Publication

Gene expression databases

BgeeiENSMUSG00000078127 Expressed in 95 organ(s), highest expression level in testis
GenevisibleiE9PXT9 MM

Interactioni

Subunit structurei

Interacts with GOPC.By similarity

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi247 – 376Gln-richPROSITE-ProRule annotationAdd BLAST130

Sequence similaritiesi

Belongs to the FAM170 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410IZBZ Eukaryota
ENOG411181D LUCA
GeneTreeiENSGT00530000063963
InParanoidiE9PXT9
OMAiHAQYGIQ
OrthoDBiEOG091G0GNZ
TreeFamiTF337124

Family and domain databases

InterProiView protein in InterPro
IPR033377 FAM170B
PANTHERiPTHR33517:SF2 PTHR33517:SF2, 1 hit

Sequencei

Sequence statusi: Complete.

E9PXT9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKHHLIEHRG EQTPGTAVGM ASPDAAEEST GVCWPGGAMR RNESSPRPGP
60 70 80 90 100
AFLPDDDIYL AARAQGVLGW SSSPSSQSSS EYQSYSQYQS WDSSKSEEQQ
110 120 130 140 150
ETPPESVCAL YTHVQTVRGV AVAWETDDGF EPVTRKPLIR EAEFIKRQRR
160 170 180 190 200
KGSSFEMASN TDLRWELEDC KHYCPQTEDP VDCCMQELRA PPDWLVTTNH
210 220 230 240 250
GLRCVACCRV FPTLEALLDH AQHGIQDGFS CQIFFEEMLE RKRTRDQKQD
260 270 280 290 300
QQPVEEEQSL SDSSECTRLL TKVLPWQQQP QQQPQEQQKQ QQQQQQKQRQ
310 320 330 340 350
QEQQQHQQQQ QQPQPLKQQQ QQQQQQPLQP QPLKQQPLQP LQPQPQPQPQ
360 370
KQQQRQQQRQ QQPPRQQQKQ QPLQQQGK
Length:378
Mass (Da):43,766
Last modified:April 5, 2011 - v1
Checksum:i2D8AF2CE6CB13D53
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC133585 Genomic DNA No translation available.
CCDSiCCDS49439.1
RefSeqiNP_001157957.1, NM_001164485.1
UniGeneiMm.32231

Genome annotation databases

EnsembliENSMUST00000104926; ENSMUSP00000100529; ENSMUSG00000078127
GeneIDi105511
KEGGimmu:105511
UCSCiuc011ziq.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC133585 Genomic DNA No translation available.
CCDSiCCDS49439.1
RefSeqiNP_001157957.1, NM_001164485.1
UniGeneiMm.32231

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

PTM databases

PhosphoSitePlusiE9PXT9

Proteomic databases

PaxDbiE9PXT9
PRIDEiE9PXT9

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000104926; ENSMUSP00000100529; ENSMUSG00000078127
GeneIDi105511
KEGGimmu:105511
UCSCiuc011ziq.1 mouse

Organism-specific databases

CTDi170370
MGIiMGI:2145650 Fam170b

Phylogenomic databases

eggNOGiENOG410IZBZ Eukaryota
ENOG411181D LUCA
GeneTreeiENSGT00530000063963
InParanoidiE9PXT9
OMAiHAQYGIQ
OrthoDBiEOG091G0GNZ
TreeFamiTF337124

Miscellaneous databases

PROiPR:E9PXT9
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000078127 Expressed in 95 organ(s), highest expression level in testis
GenevisibleiE9PXT9 MM

Family and domain databases

InterProiView protein in InterPro
IPR033377 FAM170B
PANTHERiPTHR33517:SF2 PTHR33517:SF2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF170B_MOUSE
AccessioniPrimary (citable) accession number: E9PXT9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 17, 2016
Last sequence update: April 5, 2011
Last modified: November 7, 2018
This is version 51 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again