Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 73 (08 May 2019)
Sequence version 1 (05 Apr 2011)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein
Submitted name:

Zinc finger protein 712

Gene

Zfp712

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-212436 Generic Transcription Pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Zinc finger protein 712Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Zfp712Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 13

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1925501 Zfp712

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
E9PXJ4

MaxQB - The MaxQuant DataBase

More...
MaxQBi
E9PXJ4

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
E9PXJ4

PeptideAtlas

More...
PeptideAtlasi
E9PXJ4

PRoteomics IDEntifications database

More...
PRIDEi
E9PXJ4

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
E9PXJ4

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
E9PXJ4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000090641 Expressed in 89 organ(s), highest expression level in testis

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
E9PXJ4 MM

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
E9PXJ4

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini5 – 76KRABInterPro annotationAdd BLAST72
Domaini109 – 136C2H2-typeInterPro annotationAdd BLAST28
Domaini137 – 164C2H2-typeInterPro annotationAdd BLAST28
Domaini165 – 191C2H2-typeInterPro annotationAdd BLAST27
Domaini192 – 219C2H2-typeInterPro annotationAdd BLAST28
Domaini220 – 247C2H2-typeInterPro annotationAdd BLAST28
Domaini248 – 275C2H2-typeInterPro annotationAdd BLAST28
Domaini276 – 303C2H2-typeInterPro annotationAdd BLAST28
Domaini304 – 331C2H2-typeInterPro annotationAdd BLAST28
Domaini332 – 359C2H2-typeInterPro annotationAdd BLAST28
Domaini360 – 387C2H2-typeInterPro annotationAdd BLAST28
Domaini388 – 415C2H2-typeInterPro annotationAdd BLAST28
Domaini416 – 443C2H2-typeInterPro annotationAdd BLAST28
Domaini444 – 471C2H2-typeInterPro annotationAdd BLAST28
Domaini472 – 499C2H2-typeInterPro annotationAdd BLAST28
Domaini500 – 527C2H2-typeInterPro annotationAdd BLAST28
Domaini528 – 555C2H2-typeInterPro annotationAdd BLAST28
Domaini556 – 583C2H2-typeInterPro annotationAdd BLAST28
Domaini584 – 611C2H2-typeInterPro annotationAdd BLAST28
Domaini612 – 639C2H2-typeInterPro annotationAdd BLAST28
Domaini640 – 667C2H2-typeInterPro annotationAdd BLAST28
Domaini668 – 695C2H2-typeInterPro annotationAdd BLAST28

Keywords - Domaini

RepeatSAAS annotation, Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721 Eukaryota
COG5048 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155274

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
E9PXJ4

KEGG Orthology (KO)

More...
KOi
K09228

Identification of Orthologs from Complete Genome Data

More...
OMAi
KISCTNV

Database of Orthologous Groups

More...
OrthoDBi
1318335at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
E9PXJ4

TreeFam database of animal gene trees

More...
TreeFami
TF343410

Family and domain databases

Conserved Domains Database

More...
CDDi
cd07765 KRAB_A-box, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 17 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 21 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 12 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 20 hits
PS50157 ZINC_FINGER_C2H2_2, 21 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

E9PXJ4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEEMLSFRDV AIDFSEEEWE CLEPAQWDLY RDVMLENYSH LVFLGLAFSK
60 70 80 90 100
PYLVTFLEQR REPWNVKEAA TVAAHPGIKP YTFKECGKTF PWNSLLIQQH
110 120 130 140 150
KIRPGAKLYK CDECGKSFNV RSTLYKHHRT HTGEKPYKCK ECGKAFTCSS
160 170 180 190 200
SLNQHHRIHT GEKPYKCECG KAFNNSSALT QHQRIHTGER PYKCEECGKA
210 220 230 240 250
FNNCSARTRH QRIHTGERPY KCAECGKTFN FPTSLSQHQR IHTGEKPYKC
260 270 280 290 300
EECGKAFNCS SHLKQHRIIH TGKKPYKCKE CSKAFNCSSS LNQHRRIHTG
310 320 330 340 350
EKRYICEECG KAFNNCSALT QHQRIHSGEK PYKCEECGKA FYNCSALSRH
360 370 380 390 400
QKIHTGEKPY KCAECGKAFI FRSSLSQHQR IHTGEKPYKC KECGKAFNCS
410 420 430 440 450
SHLNQHGRIH SGEKPYKCEE CGQTFICSSY LHKHQKIHAI EKLYECKECG
460 470 480 490 500
KTFSCSSYLK YHQRFHTGGK SYTCKECDKT FRSSSYLRNH QRFHTGEKPY
510 520 530 540 550
TCKECGKAFV NSSSLLVHQR IHTGEKPYKC KECGKAFRCS SYFKYHQRLH
560 570 580 590 600
TGEKPYTCKE CGKAFAKSSC LILHQRIHTG EKPYKCEECG QAFICSSYLR
610 620 630 640 650
KHQRIHTGEK PYTCEECGKA FSIYSTYAQH QRIHTGEKPY KCKECDKAFN
660 670 680 690 700
NHSALIKHQR IHTGEKPYAC KECSKAFNNS SSLIRHQRIH IGIETLEIQG

IWQGL
Length:705
Mass (Da):81,681
Last modified:April 5, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA436B032B36A9532
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC124433 Genomic DNA No translation available.
AC187103 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
NP_001159690.1, NM_001166218.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000167565; ENSMUSP00000126665; ENSMUSG00000090641

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
78251

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:78251

UCSC genome browser

More...
UCSCi
uc007rab.2 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124433 Genomic DNA No translation available.
AC187103 Genomic DNA No translation available.
RefSeqiNP_001159690.1, NM_001166218.1

3D structure databases

SMRiE9PXJ4
ModBaseiSearch...
MobiDBiSearch...

PTM databases

iPTMnetiE9PXJ4
PhosphoSitePlusiE9PXJ4

Proteomic databases

jPOSTiE9PXJ4
MaxQBiE9PXJ4
PaxDbiE9PXJ4
PeptideAtlasiE9PXJ4
PRIDEiE9PXJ4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000167565; ENSMUSP00000126665; ENSMUSG00000090641
GeneIDi78251
KEGGimmu:78251
UCSCiuc007rab.2 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
78251
MGIiMGI:1925501 Zfp712

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00940000155274
InParanoidiE9PXJ4
KOiK09228
OMAiKISCTNV
OrthoDBi1318335at2759
PhylomeDBiE9PXJ4
TreeFamiTF343410

Enzyme and pathway databases

ReactomeiR-MMU-212436 Generic Transcription Pathway

Miscellaneous databases

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000090641 Expressed in 89 organ(s), highest expression level in testis
GenevisibleiE9PXJ4 MM

Family and domain databases

CDDicd07765 KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 17 hits
SMARTiView protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 21 hits
SUPFAMiSSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 12 hits
PROSITEiView protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 20 hits
PS50157 ZINC_FINGER_C2H2_2, 21 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiE9PXJ4_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E9PXJ4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: May 8, 2019
This is version 73 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again