UniProtKB - E9PXF8 (E9PXF8_MOUSE)

BLAST

>tr|E9PXF8|E9PXF8_MOUSE SET-binding factor 2 OS=Mus musculus OX=10090 GN=Sbf2 PE=1 SV=1
MARLADYFIVVGYDHEKPAGPGEGLGKIIQRFPQQDWDDTPFPQGIELFCQPGGWHLSRE
RKQPTFFVVVLTDIDSDRHYCSCLTFYEAEINLQGTKKEEIEGEEVSGLIQPAEVFAPKS
LVLVSRLDYPEIFRACLGLIYTVYVDSMSVSLESLIANLCACLVPAAGGSQKLFSLGAGD
RQLIQTPLHDSLPVTGTSVALLFQQLGIQNVLNLFCAVLTENKVLFHSASFQRLSDACRA
LESLMFPLKYSYPYIPILPAQLLEVLSSPTPFIIGVHSIFKTDVHELLDVIIADLDGGTI
KIPECIHLSSLPEPLLHQTQSALSLILHPDLEVADHAFPPPRTALSHSKMLDKEVRAVFL
RLFAQLFQGYRSCLQLIRIHAEPVIHFHKTAFLGQRGLVENDFLTKVLNGMAFAGFVSER
GPPYRACDLFDELVAFEVERIKVEEKNPLKMIKHIRELAEQLFKNENPNPHMAFQKVPRP
TEGSHLRVHILPFPKINEARVQELIQENLAKNQNAPPATRIEKKCVVPAGPPVVSIMEKV
ITVFNSAQRLEVVRNCISFIFENKTLETEKTLPAALRALKGKAARQCLTDELGLHVQQNR
AILDHQQFDYIIRMMNCTLQDCSSLEEYNIAAALLPLTSAFYRKLAPGVSQFAYTCVQDH
PIWTNQQFWETTFYNAVQEQVRSLYLSAKDDNHIPHLKQKLPDGQHQEKTAMDLAAEQLR
LWPTLSKSTQQELVQHEESTVFSQAIHFANLMVNLLVPLDTSKNKLLRASAPGDWESGSN
SIVTNSIAGSVAESYDTESGFEDSENSDVANSVVRFIARFIDKVCTESGVTQDHIRSLHC
MIPGIVAMHIETLEAVHRESRRLPPIQKPKILRPALLPGEEIVCEGLRVLLDPDGREEAT
GGLLGGPQLLPAEGALFLTTYRILFRGTPHDQLVGEQTVVRSFPIASITKEKKITMQNQL
QQSVQEGLQITSASFQLIKVAFDEEVSPEVVDIFKKQLMKFRYPQSIFSTFAFAAGQTTP
QIILPKQKEKNTSFRTFSKTIVKGAKKAGKMTIGRQYLLKKRTGTIVEERVNRPGWNEED
DISVSDDSELPTSTTLKASEKSTMEQLVEKACFRDYQRLGLGTISGNSSRSKPEYFRVTA
SNRLYSLCRSYPGLLVIPQAVQDSSLPRVARCYRHNRLPVVCWKNSRSGTLLLRSGGFHG
KGVVGLFKSQNSPQAVSTSSLESSSSIEQEKYLQALLTAVIVHQKLRGSSTLTVRPALAL
SPVHGYRDKSFTQSNPKSSAKEPVHNQGVWASLRSSTRLISSPTSFIDVGARLAGKDHSA
SFSNSTYLQNQLLKRQAALYIFGEKSQLRSSKVEFAFNCEFVPVEFHEIRQVKASFKKLM
RACIPSTIPTDSEVTFLKALGDSEWFPQLHRIMQLAVVVSEVLENGSSVWVCLEEGWDIT
TQVTSLAQLLSDPFYRTIAGFRTLVEKEWLSFGHKFSQRSSLALNSQGGGFAPIFLQFLD
CVHQVHNQYPTEFEFNLYYLKFLAFHYVSNRFKTFLLDSDYERLEHGTLFDDKGDKHAKK
GVCIWECIDKMHTRSPIFFNYLYSPVEVEALKPNVNVSSLKKWDYYTEETLSAGPSYDWM
MLTPKHFPYEESDVAGGAGPQSQRKTVWPCYDDVTCSQPDALTRLFSEIEKLEHKLNQTP
ERWHQLWEKVTTDLKEEPRTAHSLRHSAGSPGIASTNVPSYQKRPALHPLHRGLGEDQST
TTAPSNGVEHRAATLYSQYTSKNDENRSFEGTLYKRGALLKGWKPRWFVLDVTKHQLRYY
DSGEDTSCKGHIDLAEVEMVIPAGPSMGAPKYTSDKAFFDLKTSKRVYNFCAQDGQSAQQ
WMDRIQSCISDA

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History
Entry version 69 (07 Nov 2018)
Sequence version 1 (05 Apr 2011)
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Protein

Submitted name:

SET-binding factor 2

Gene

Sbf2

Organism

Mus musculus (Mouse)

Status

Unreviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

GO - Molecular functionⁱ

phosphatase binding
Source: MGI
Inferred from physical interactionⁱ
- 16399794
phosphatase regulator activity
Source: MGI
Inferred from direct assayⁱ
- 16399794
phosphatidylinositol binding
Source: MGI
Inferred from direct assayⁱ
- 16399794
protein homodimerization activity
Source: MGI
Inferred from physical interactionⁱ
- 16399794
Rab guanyl-nucleotide exchange factor activity Source: MGI

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

protein tetramerization
Source: MGI
Inferred from physical interactionⁱ
- 16399794
regulation of GTPase activity Source: InterPro

View the complete GO annotation on QuickGO ...

Enzyme and pathway databases

Reactomeⁱ	R-MMU-8876198 RAB GEFs exchange GTP for GDP on RABs

Reactomeⁱ

R-MMU-8876198 RAB GEFs exchange GTP for GDP on RABs

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: SET-binding factor 2Imported
Gene namesⁱ	Name:Sbf2Imported
Organismⁱ	Mus musculus (Mouse)Imported
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 7

Organism-specific databases

MGIⁱ	MGI:1921831 Sbf2

Subcellular locationⁱ

GO - Cellular component

PTM / Processingⁱ

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	E9PXF8
PaxDbⁱ	E9PXF8
PeptideAtlas More...PeptideAtlasⁱ	E9PXF8
PRIDEⁱ	E9PXF8

PTM databases

iPTMnetⁱ	E9PXF8
PhosphoSitePlusⁱ	E9PXF8

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSMUSG00000038371 Expressed in 288 organ(s), highest expression level in sciatic nerve
ExpressionAtlasⁱ	E9PXF8 baseline and differential
Genevisibleⁱ	E9PXF8 MM

Interactionⁱ

GO - Molecular functionⁱ

phosphatase binding
Source: MGI
Inferred from physical interactionⁱ
- 16399794
protein homodimerization activity
Source: MGI
Inferred from physical interactionⁱ
- 16399794
Rab guanyl-nucleotide exchange factor activity Source: MGI

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

STRINGⁱ	10090.ENSMUSP00000033058

STRINGⁱ

10090.ENSMUSP00000033058

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	E9PXF8
SMRⁱ	E9PXF8
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Domainⁱ	7 – 427	UDENNInterPro annotationAdd BLAST	421
Domainⁱ	1106 – 1607	Myotubularin phosphataseInterPro annotationAdd BLAST	502
Domainⁱ	1766 – 1870	PHInterPro annotationAdd BLAST	105

Sequence similaritiesⁱ

Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.SAAS annotation

Phylogenomic databases

eggNOGⁱ	KOG1090 Eukaryota KOG4471 Eukaryota ENOG410XTJ1 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000118832
InParanoidⁱ	E9PXF8
KEGG Orthology (KO) More...KOⁱ	K18061
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G00CQ
TreeFamⁱ	TF318583

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd13339 PH-GRAM_MTMR13, 1 hit
Gene3Dⁱ	2.30.29.30, 1 hit
InterProⁱ	View protein in InterPro IPR001194 cDENN_dom IPR005112 dDENN_dom IPR004182 GRAM IPR030567 MTMR13 IPR037823 MTMR13_PH-GRAM IPR010569 Myotubularin-like_Pase_dom IPR030564 Myotubularin_fam IPR011993 PH-like_dom_sf IPR001849 PH_domain IPR029021 Prot-tyrosine_phosphatase-like IPR022096 SBF1/SBF2 IPR037516 Tripartite_DENN IPR005113 uDENN_dom
PANTHERⁱ	PTHR10807 PTHR10807, 1 hit PTHR10807:SF4 PTHR10807:SF4, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF02141 DENN, 1 hit PF02893 GRAM, 1 hit PF06602 Myotub-related, 1 hit PF00169 PH, 1 hit PF12335 SBF2, 1 hit PF03456 uDENN, 1 hit
SMARTⁱ	View protein in SMART SM00801 dDENN, 1 hit SM00799 DENN, 1 hit SM00568 GRAM, 1 hit SM00233 PH, 1 hit SM00800 uDENN, 1 hit
SUPFAMⁱ	SSF52799 SSF52799, 1 hit
PROSITEⁱ	View protein in PROSITE PS50211 DENN, 1 hit PS50003 PH_DOMAIN, 1 hit PS51339 PPASE_MYOTUBULARIN, 1 hit

Sequence (1+)ⁱ

Sequence statusⁱ: Complete.

This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show all Align All

E9PXF8-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MARLADYFIV VGYDHEKPAG PGEGLGKIIQ RFPQQDWDDT PFPQGIELFC 
        60         70         80         90        100
QPGGWHLSRE RKQPTFFVVV LTDIDSDRHY CSCLTFYEAE INLQGTKKEE 
       110        120        130        140        150
IEGEEVSGLI QPAEVFAPKS LVLVSRLDYP EIFRACLGLI YTVYVDSMSV 
       160        170        180        190        200
SLESLIANLC ACLVPAAGGS QKLFSLGAGD RQLIQTPLHD SLPVTGTSVA 
       210        220        230        240        250
LLFQQLGIQN VLNLFCAVLT ENKVLFHSAS FQRLSDACRA LESLMFPLKY 
       260        270        280        290        300
SYPYIPILPA QLLEVLSSPT PFIIGVHSIF KTDVHELLDV IIADLDGGTI 
       310        320        330        340        350
KIPECIHLSS LPEPLLHQTQ SALSLILHPD LEVADHAFPP PRTALSHSKM 
       360        370        380        390        400
LDKEVRAVFL RLFAQLFQGY RSCLQLIRIH AEPVIHFHKT AFLGQRGLVE 
       410        420        430        440        450
NDFLTKVLNG MAFAGFVSER GPPYRACDLF DELVAFEVER IKVEEKNPLK 
       460        470        480        490        500
MIKHIRELAE QLFKNENPNP HMAFQKVPRP TEGSHLRVHI LPFPKINEAR 
       510        520        530        540        550
VQELIQENLA KNQNAPPATR IEKKCVVPAG PPVVSIMEKV ITVFNSAQRL 
       560        570        580        590        600
EVVRNCISFI FENKTLETEK TLPAALRALK GKAARQCLTD ELGLHVQQNR 
       610        620        630        640        650
AILDHQQFDY IIRMMNCTLQ DCSSLEEYNI AAALLPLTSA FYRKLAPGVS 
       660        670        680        690        700
QFAYTCVQDH PIWTNQQFWE TTFYNAVQEQ VRSLYLSAKD DNHIPHLKQK 
       710        720        730        740        750
LPDGQHQEKT AMDLAAEQLR LWPTLSKSTQ QELVQHEEST VFSQAIHFAN 
       760        770        780        790        800
LMVNLLVPLD TSKNKLLRAS APGDWESGSN SIVTNSIAGS VAESYDTESG 
       810        820        830        840        850
FEDSENSDVA NSVVRFIARF IDKVCTESGV TQDHIRSLHC MIPGIVAMHI 
       860        870        880        890        900
ETLEAVHRES RRLPPIQKPK ILRPALLPGE EIVCEGLRVL LDPDGREEAT 
       910        920        930        940        950
GGLLGGPQLL PAEGALFLTT YRILFRGTPH DQLVGEQTVV RSFPIASITK 
       960        970        980        990       1000
EKKITMQNQL QQSVQEGLQI TSASFQLIKV AFDEEVSPEV VDIFKKQLMK 
      1010       1020       1030       1040       1050
FRYPQSIFST FAFAAGQTTP QIILPKQKEK NTSFRTFSKT IVKGAKKAGK 
      1060       1070       1080       1090       1100
MTIGRQYLLK KRTGTIVEER VNRPGWNEED DISVSDDSEL PTSTTLKASE 
      1110       1120       1130       1140       1150
KSTMEQLVEK ACFRDYQRLG LGTISGNSSR SKPEYFRVTA SNRLYSLCRS 
      1160       1170       1180       1190       1200
YPGLLVIPQA VQDSSLPRVA RCYRHNRLPV VCWKNSRSGT LLLRSGGFHG 
      1210       1220       1230       1240       1250
KGVVGLFKSQ NSPQAVSTSS LESSSSIEQE KYLQALLTAV IVHQKLRGSS 
      1260       1270       1280       1290       1300
TLTVRPALAL SPVHGYRDKS FTQSNPKSSA KEPVHNQGVW ASLRSSTRLI 
      1310       1320       1330       1340       1350
SSPTSFIDVG ARLAGKDHSA SFSNSTYLQN QLLKRQAALY IFGEKSQLRS 
      1360       1370       1380       1390       1400
SKVEFAFNCE FVPVEFHEIR QVKASFKKLM RACIPSTIPT DSEVTFLKAL 
      1410       1420       1430       1440       1450
GDSEWFPQLH RIMQLAVVVS EVLENGSSVW VCLEEGWDIT TQVTSLAQLL 
      1460       1470       1480       1490       1500
SDPFYRTIAG FRTLVEKEWL SFGHKFSQRS SLALNSQGGG FAPIFLQFLD 
      1510       1520       1530       1540       1550
CVHQVHNQYP TEFEFNLYYL KFLAFHYVSN RFKTFLLDSD YERLEHGTLF 
      1560       1570       1580       1590       1600
DDKGDKHAKK GVCIWECIDK MHTRSPIFFN YLYSPVEVEA LKPNVNVSSL 
      1610       1620       1630       1640       1650
KKWDYYTEET LSAGPSYDWM MLTPKHFPYE ESDVAGGAGP QSQRKTVWPC 
      1660       1670       1680       1690       1700
YDDVTCSQPD ALTRLFSEIE KLEHKLNQTP ERWHQLWEKV TTDLKEEPRT 
      1710       1720       1730       1740       1750
AHSLRHSAGS PGIASTNVPS YQKRPALHPL HRGLGEDQST TTAPSNGVEH 
      1760       1770       1780       1790       1800
RAATLYSQYT SKNDENRSFE GTLYKRGALL KGWKPRWFVL DVTKHQLRYY 
      1810       1820       1830       1840       1850
DSGEDTSCKG HIDLAEVEMV IPAGPSMGAP KYTSDKAFFD LKTSKRVYNF 
      1860       1870 
CAQDGQSAQQ WMDRIQSCIS DA

Length:1,872

Mass (Da):210,458

Last modified:April 5, 2011 - v1

Checksum:ⁱF3D86BAEA404F561

Computationally mapped potential isoform sequencesⁱ

There are 8 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

E9Q305	E9Q305_MOUSE	SET-binding factor 2 SET-binding factor 2	Sbf2	1,847	Annotation score:
E9Q0D4	E9Q0D4_MOUSE	SET-binding factor 2 SET-binding factor 2	Sbf2	1,826	Annotation score:
F7BBM8	F7BBM8_MOUSE	SET-binding factor 2 SET-binding factor 2	Sbf2	245	Annotation score:
F6ZDC5	F6ZDC5_MOUSE	SET-binding factor 2 SET-binding factor 2	Sbf2	339	Annotation score:
F6QZ02	F6QZ02_MOUSE	SET-binding factor 2 SET-binding factor 2	Sbf2	198	Annotation score:
F6QG63	F6QG63_MOUSE	SET-binding factor 2 SET-binding factor 2	Sbf2	177	Annotation score:
E9Q372	E9Q372_MOUSE	SET-binding factor 2 SET-binding factor 2	Sbf2	408	Annotation score:
E9Q4I8	E9Q4I8_MOUSE	SET-binding factor 2 SET-binding factor 2	Sbf2	44	Annotation score:

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC122921 Genomic DNA No translation available. AC124472 Genomic DNA No translation available. AC154911 Genomic DNA No translation available.
NCBI Reference Sequences More...RefSeqⁱ	NP_796298.2, NM_177324.2
UniGeneⁱ	Mm.102970

Genome annotation databases

Ensemblⁱ	ENSMUST00000033058; ENSMUSP00000033058; ENSMUSG00000038371
GeneIDⁱ	319934
KEGGⁱ	mmu:319934
UCSC genome browser More...UCSCⁱ	uc009jfe.2 mouse

Protein	Similar proteins		Species	Score	Length	Source
E9PXF8	myotubularin-related protein 13 isoform X2		DELLE		1881	UniRef90_E9PXF8
Uncharacterized protein		CHLSB		1881
Uncharacterized protein		PIG		1881
myotubularin-related protein 13 isoform X1		ODORO		1878
Uncharacterized protein		RABIT		1878
+91

Protein	Similar proteins		Species	Score	Length	Source
E9PXF8	Myotubularin-related protein 5		HUMAN		1868	UniRef50_O95248
Myotubularin-related protein 5	)	MOUSE		1867
Myotubularin-related protein 13		XENLA		1873
Uncharacterized protein		CERAT		1979
myotubularin-related protein 5 isoform X4		ERIEU		1888
+905

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC122921 Genomic DNA No translation available. AC124472 Genomic DNA No translation available. AC154911 Genomic DNA No translation available.
RefSeqⁱ	NP_796298.2, NM_177324.2
UniGeneⁱ	Mm.102970

3D structure databases

ProteinModelPortalⁱ	E9PXF8
SMRⁱ	E9PXF8
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10090.ENSMUSP00000033058

STRINGⁱ

10090.ENSMUSP00000033058

PTM databases

iPTMnetⁱ	E9PXF8
PhosphoSitePlusⁱ	E9PXF8

Proteomic databases

MaxQBⁱ	E9PXF8
PaxDbⁱ	E9PXF8
PeptideAtlasⁱ	E9PXF8
PRIDEⁱ	E9PXF8

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000033058; ENSMUSP00000033058; ENSMUSG00000038371
GeneIDⁱ	319934
KEGGⁱ	mmu:319934
UCSCⁱ	uc009jfe.2 mouse

Organism-specific databases

CTDⁱ	81846
MGIⁱ	MGI:1921831 Sbf2

Phylogenomic databases

eggNOGⁱ	KOG1090 Eukaryota KOG4471 Eukaryota ENOG410XTJ1 LUCA
GeneTreeⁱ	ENSGT00760000118832
InParanoidⁱ	E9PXF8
KOⁱ	K18061
OrthoDBⁱ	EOG091G00CQ
TreeFamⁱ	TF318583

Enzyme and pathway databases

Reactomeⁱ	R-MMU-8876198 RAB GEFs exchange GTP for GDP on RABs

Reactomeⁱ

R-MMU-8876198 RAB GEFs exchange GTP for GDP on RABs

Miscellaneous databases

ChiTaRSⁱ	Sbf2 mouse
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000038371 Expressed in 288 organ(s), highest expression level in sciatic nerve
ExpressionAtlasⁱ	E9PXF8 baseline and differential
Genevisibleⁱ	E9PXF8 MM

Family and domain databases

CDDⁱ	cd13339 PH-GRAM_MTMR13, 1 hit
Gene3Dⁱ	2.30.29.30, 1 hit
InterProⁱ	View protein in InterPro IPR001194 cDENN_dom IPR005112 dDENN_dom IPR004182 GRAM IPR030567 MTMR13 IPR037823 MTMR13_PH-GRAM IPR010569 Myotubularin-like_Pase_dom IPR030564 Myotubularin_fam IPR011993 PH-like_dom_sf IPR001849 PH_domain IPR029021 Prot-tyrosine_phosphatase-like IPR022096 SBF1/SBF2 IPR037516 Tripartite_DENN IPR005113 uDENN_dom
PANTHERⁱ	PTHR10807 PTHR10807, 1 hit PTHR10807:SF4 PTHR10807:SF4, 1 hit
Pfamⁱ	View protein in Pfam PF02141 DENN, 1 hit PF02893 GRAM, 1 hit PF06602 Myotub-related, 1 hit PF00169 PH, 1 hit PF12335 SBF2, 1 hit PF03456 uDENN, 1 hit
SMARTⁱ	View protein in SMART SM00801 dDENN, 1 hit SM00799 DENN, 1 hit SM00568 GRAM, 1 hit SM00233 PH, 1 hit SM00800 uDENN, 1 hit
SUPFAMⁱ	SSF52799 SSF52799, 1 hit
PROSITEⁱ	View protein in PROSITE PS50211 DENN, 1 hit PS50003 PH_DOMAIN, 1 hit PS51339 PPASE_MYOTUBULARIN, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	E9PXF8_MOUSE
Accessionⁱ	E9PXF8Primary (citable) accession number: E9PXF8
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	April 5, 2011
	Last sequence update:	April 5, 2011
	Last modified:	November 7, 2018
	This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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UniProtKB - E9PXF8 (E9PXF8_MOUSE)

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SET-binding factor 2

Sbf2

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Other locations

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ