Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 69 (16 Oct 2019)
Sequence version 1 (05 Apr 2011)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

ATP-binding cassette sub-family A member 17

Gene

Abca17

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Promotes cholesterol efflux from sperm which renders sperm capable of fertilization (PubMed:22237709). Has also been shown to decrease levels of intracellular esterified neutral lipids including cholesteryl esters, fatty acid esters and triacylglycerols (PubMed:15810880).2 Publications

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi555 – 562ATPPROSITE-ProRule annotation8
Nucleotide bindingi1401 – 1408ATPPROSITE-ProRule annotation8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processLipid metabolism, Lipid transport, Transport
LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
ATP-binding cassette sub-family A member 17Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Abca17Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:3625331 Abca17

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei22 – 42HelicalSequence analysisAdd BLAST21
Transmembranei262 – 282HelicalSequence analysisAdd BLAST21
Transmembranei306 – 326HelicalSequence analysisAdd BLAST21
Transmembranei342 – 362HelicalSequence analysisAdd BLAST21
Transmembranei372 – 392HelicalSequence analysisAdd BLAST21
Transmembranei403 – 423HelicalSequence analysisAdd BLAST21
Transmembranei444 – 464HelicalSequence analysisAdd BLAST21
Transmembranei906 – 926HelicalSequence analysisAdd BLAST21
Transmembranei1082 – 1102HelicalSequence analysisAdd BLAST21
Transmembranei1128 – 1148HelicalSequence analysisAdd BLAST21
Transmembranei1160 – 1180HelicalSequence analysisAdd BLAST21
Transmembranei1192 – 1212HelicalSequence analysisAdd BLAST21
Transmembranei1230 – 1250HelicalSequence analysisAdd BLAST21
Transmembranei1287 – 1307HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Cytoplasm, Endoplasmic reticulum, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004364761 – 1733ATP-binding cassette sub-family A member 17Add BLAST1733

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi609N-linked (GlcNAc...) asparagineSequence analysis1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

N-glycosylated.1 Publication

Keywords - PTMi

Glycoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
E9PX95

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
E9PX95

PRoteomics IDEntifications database

More...
PRIDEi
E9PX95

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

In the testis, detected predominantly in elongated spermatids at the late stage of germ cell development and in sperm, with no expression detected in immature germ cells such as spermatogonia and spermatocytes or in somatic cells such as Sertoli cells (at protein level) (PubMed:15810880). Expressed in the head and tail midpiece of elongated spermatids and sperm (at protein level) (PubMed:22237709). Expressed exclusively in the testis (PubMed:15810880, PubMed:22237709).2 Publications

<p>This subsection of the ‘Expression’ section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified ‘at the protein level’.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Detected in the testis at low levels at postnatal day 5 but increases at postnatal days 20 and 45 (at protein level).1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000035435 Expressed in 7 organ(s), highest expression level in testis

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000112538

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
E9PX95

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini519 – 752ABC transporter 1PROSITE-ProRule annotationAdd BLAST234
Domaini1366 – 1599ABC transporter 2PROSITE-ProRule annotationAdd BLAST234

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1698 – 1730Pro-richPROSITE-ProRule annotationAdd BLAST33

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0059 Eukaryota
COG1131 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000163933

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000006613

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
E9PX95

KEGG Orthology (KO)

More...
KOi
K05643

Identification of Orthologs from Complete Genome Data

More...
OMAi
KFQLVYI

Database of Orthologous Groups

More...
OrthoDBi
131191at2759

TreeFam database of animal gene trees

More...
TreeFami
TF105191

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003593 AAA+_ATPase
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR026082 ABCA
IPR027417 P-loop_NTPase

The PANTHER Classification System

More...
PANTHERi
PTHR19229 PTHR19229, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00005 ABC_tran, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00382 AAA, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00211 ABC_TRANSPORTER_1, 1 hit
PS50893 ABC_TRANSPORTER_2, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

E9PX95-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEVLKKLKLL LWKNFILKRR KTLITLLEML MPLLFCAIVL YLRLNSMPRK
60 70 80 90 100
KSSTNYPAVD VSLLPVYFYN YPLKSKFQLA YIPSKSETLK AVTEVVEQTF
110 120 130 140 150
AVDFEVLGFP SVPLFEDYII KDPKSFYILV GIIFHHDFNS SNEPLPLVVK
160 170 180 190 200
YDLRFSYVQR NFVSPPRHLF FQEEIEGWCT AFLYPPNLSQ APREFSYADG
210 220 230 240 250
GNPGYNKEGF LAIQHAVDKA IMRHHAPKAA LNMFKDLHVL VQRFPFGPHI
260 270 280 290 300
QDPFLVILQN EFPLLLMLSF ICVELIITNS VLSEKERKQK EYMSMMGVES
310 320 330 340 350
WLHWVAWFIT FFISVSITVS VMTVLFCTKI NRVAVFRNSN PTLIFIFLMC
360 370 380 390 400
FAIATIFFAF MMSTFFQRAH VGTVIGGTVF FFTYLPYMYI TFSYHQRTYT
410 420 430 440 450
QKILSCLFSN VAMATGVRFI SLFEAEGTGI QWRNIGSVWG DFSFAQVLGM
460 470 480 490 500
LLLDSFLYCL IAFLVESLFP RKFGIPKSWY IFAKKPVPEI PPLLNIGDPE
510 520 530 540 550
KPSKGNFMQD EPTNQMNTIE IQHLYKVFYS GRSKRTAIRD LSMNLYKGQV
560 570 580 590 600
TVLLGHNGAG KTTVCSVLTG LITPSKGHAY IHGCEISKDM VQIRKSLGWC
610 620 630 640 650
PQHDILFDNF TVTDHLYFYG QLKGLSPQDC HEQTQEMLHL LGLKDKWNSR
660 670 680 690 700
SKFLSGGMKR KLSIGIALIA GSKVLILDEP TSGLDSPSRR AIWDLLQQQK
710 720 730 740 750
GDRTVLLTTH FMDEADLLGD RIAILAKGEL QCCGSPSFLK QKYGAGYYMT
760 770 780 790 800
IIKTPLCDTS KLSEVIYHHI PNAVLESNIG EEMIVTLPKK TIHRFEALFN
810 820 830 840 850
DLELRQTELG ISTFATSVTT MEEVFIRVCK LADPSTNVLT EKRHSLHPLP
860 870 880 890 900
RHHRVPVDRI KCLHSGTFPV STEQPMRLNT GFCLLCQQFY AMLLKKITYS
910 920 930 940 950
RRNWMLVLSV QVLLPLAIIM LSLTFFNFKL RKLDNVPLEL TLQTYGQTIV
960 970 980 990 1000
PFFIAENSHL DPQLSDDFVK MLVAAGQVPL RIQGSVEDFL LKKAKEAPEG
1010 1020 1030 1040 1050
FDKLYVVAAS FEDVNNHTTV KALFNNQAYH SPSLALTLVD NLLFKLLSGA
1060 1070 1080 1090 1100
NASITTTNYP QPQTAIEVSE SILYQGPKGH YLVVNFLFGI AFLSSSFSIL
1110 1120 1130 1140 1150
TVGEKSVKSK SLQFVSGVST AVFWLSALLW DLISFLVPTL LLVLVFLWYK
1160 1170 1180 1190 1200
EEAFAHHESI PAVVLIMMLY GWAVIPLVYT VSFSFNTPGS ACVKLVVMLT
1210 1220 1230 1240 1250
FLSISPVVLV TVTSEKDLGY TELSDSLDHI FLILPGHCLG MALSNLYYNF
1260 1270 1280 1290 1300
ELKKFCSAKN LSDIDCNDVL EGYVVQENIY AWESLGIGKY LTALAVLGPV
1310 1320 1330 1340 1350
YITMLFLTEA NAFYVLKSRL SGFFPSFWKE KSGMIFDVAE PEDEDVLEEA
1360 1370 1380 1390 1400
ETIKRYLETL VKKNPLVVKE VSKVYKDKVP LLAVNKVSFV VKEEECFGLL
1410 1420 1430 1440 1450
GLNGAGKTSI FNMLTSEQPI TSGDAFVKGF NIKSDIAKVR QWIGYCPEFD
1460 1470 1480 1490 1500
ALLNFMTGRE MLVMYARIRG IPECHIKACV DLILENLLMC VCADKLVKTY
1510 1520 1530 1540 1550
SGGNKRMLST GIALVGEPAV ILLDEPSTGM DPVARRLLWD TVERVRESGK
1560 1570 1580 1590 1600
TIVITSHSME ECEALCTRLA IMVQGQFKCL GSPQHLKSKF GISYSLQAKV
1610 1620 1630 1640 1650
RRKWQQQMLE EFKAFVDLTF PGSNLEDEHQ NMLQYYLPGP NLSWAKVFSI
1660 1670 1680 1690 1700
MEQAKKDYML EDYSISQLSL EDIFLNFTRP ESSTKEQIQQ EQAVLASPSP
1710 1720 1730
PSNSRPISSP PSRLSSPTPK PLPSPPPSEP ILL
Length:1,733
Mass (Da):196,020
Last modified:April 5, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i91CAA7309F01BF81
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A3Q4ECA2A0A3Q4ECA2_MOUSE
ATP-binding cassette sub-family A m...
Abca17
214Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti67Y → C in BAD97416 (PubMed:15810880).Curated1
Sequence conflicti415T → M in BAD97416 (PubMed:15810880).Curated1
Sequence conflicti652K → R in BAD97416 (PubMed:15810880).Curated1
Sequence conflicti657G → D in BAD97416 (PubMed:15810880).Curated1
Sequence conflicti1166I → L in BAD97416 (PubMed:15810880).Curated1
Sequence conflicti1350 – 1355AETIKR → TEAIKH in BAD97416 (PubMed:15810880).Curated6
Sequence conflicti1361V → I in BAD97416 (PubMed:15810880).Curated1
Sequence conflicti1378K → E in BAD97416 (PubMed:15810880).Curated1
Sequence conflicti1394E → G in BAD97416 (PubMed:15810880).Curated1
Sequence conflicti1578K → E in BAD97416 (PubMed:15810880).Curated1
Sequence conflicti1593S → G in BAD97416 (PubMed:15810880).Curated1
Sequence conflicti1694V → A in BAD97416 (PubMed:15810880).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB112584 mRNA Translation: BAD97416.1
AC117577 Genomic DNA No translation available.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS37485.1

NCBI Reference Sequences

More...
RefSeqi
NP_001026792.2, NM_001031621.2
XP_006524539.1, XM_006524476.3
XP_006524540.1, XM_006524477.3
XP_006524541.1, XM_006524478.3
XP_006524542.1, XM_006524479.3
XP_017173021.1, XM_017317532.1
XP_017173022.1, XM_017317533.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000039324; ENSMUSP00000046218; ENSMUSG00000035435
ENSMUST00000121226; ENSMUSP00000112538; ENSMUSG00000035435

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
381072

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:381072

UCSC genome browser

More...
UCSCi
uc008avk.1 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB112584 mRNA Translation: BAD97416.1
AC117577 Genomic DNA No translation available.
CCDSiCCDS37485.1
RefSeqiNP_001026792.2, NM_001031621.2
XP_006524539.1, XM_006524476.3
XP_006524540.1, XM_006524477.3
XP_006524541.1, XM_006524478.3
XP_006524542.1, XM_006524479.3
XP_017173021.1, XM_017317532.1
XP_017173022.1, XM_017317533.1

3D structure databases

SMRiE9PX95
ModBaseiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000112538

Proteomic databases

MaxQBiE9PX95
PaxDbiE9PX95
PRIDEiE9PX95

Genome annotation databases

EnsembliENSMUST00000039324; ENSMUSP00000046218; ENSMUSG00000035435
ENSMUST00000121226; ENSMUSP00000112538; ENSMUSG00000035435
GeneIDi381072
KEGGimmu:381072
UCSCiuc008avk.1 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
381072
MGIiMGI:3625331 Abca17

Phylogenomic databases

eggNOGiKOG0059 Eukaryota
COG1131 LUCA
GeneTreeiENSGT00940000163933
HOGENOMiHOG000006613
InParanoidiE9PX95
KOiK05643
OMAiKFQLVYI
OrthoDBi131191at2759
TreeFamiTF105191

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Abca17 mouse

Protein Ontology

More...
PROi
PR:E9PX95

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000035435 Expressed in 7 organ(s), highest expression level in testis

Family and domain databases

InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR026082 ABCA
IPR027417 P-loop_NTPase
PANTHERiPTHR19229 PTHR19229, 1 hit
PfamiView protein in Pfam
PF00005 ABC_tran, 2 hits
SMARTiView protein in SMART
SM00382 AAA, 2 hits
SUPFAMiSSF52540 SSF52540, 2 hits
PROSITEiView protein in PROSITE
PS00211 ABC_TRANSPORTER_1, 1 hit
PS50893 ABC_TRANSPORTER_2, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiABCAH_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E9PX95
Secondary accession number(s): Q4H4D7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 8, 2016
Last sequence update: April 5, 2011
Last modified: October 16, 2019
This is version 69 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again