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Protein
Submitted name:

Remodeling and spacing factor 1

Gene

Rsf1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • histone acetyltransferase activity Source: GO_Central
  • histone binding Source: MGI
  • metal ion binding Source: UniProtKB-KW

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Remodeling and spacing factor 1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Rsf1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2682305 Rsf1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
E9PWW9

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
E9PWW9

PeptideAtlas

More...
PeptideAtlasi
E9PWW9

PRoteomics IDEntifications database

More...
PRIDEi
E9PWW9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000035623 Expressed in 249 organ(s), highest expression level in manus

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
E9PWW9 baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-463 RSF complex

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000037409

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
E9PWW9

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
E9PWW9

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini894 – 944PHD-typeInterPro annotationAdd BLAST51

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili947 – 970Sequence analysisAdd BLAST24
Coiled coili993 – 1014Sequence analysisAdd BLAST22

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IFYI Eukaryota
ENOG410YTDT LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00530000064411

KEGG Orthology (KO)

More...
KOi
K11657

Identification of Orthologs from Complete Genome Data

More...
OMAi
RQINYKE

Database of Orthologous Groups

More...
OrthoDBi
917466at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR028938 Rsf-1
IPR028942 WHIM1_dom
IPR019786 Zinc_finger_PHD-type_CS
IPR011011 Znf_FYVE_PHD
IPR001965 Znf_PHD
IPR019787 Znf_PHD-finger
IPR013083 Znf_RING/FYVE/PHD

The PANTHER Classification System

More...
PANTHERi
PTHR10615:SF156 PTHR10615:SF156, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00628 PHD, 1 hit
PF15612 WHIM1, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00249 PHD, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57903 SSF57903, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01359 ZF_PHD_1, 1 hit
PS50016 ZF_PHD_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

E9PWW9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAAAAAAAA AAAAAMAPPG CPGSCPNFAV VCSFLERYGP LLDLPELPFP
60 70 80 90 100
ELERVLQAPP PDIGNGEVPK ELVELHLKLM RKIGKSVTAD RWEKYLIKIC
110 120 130 140 150
QEFNSTWAWE MEKKGYLEMS VECKLALLKY LCECQFDDNL KFKNIINEED
160 170 180 190 200
ADTMRLQPIG RDKDGLMYWY QLDQDHNVRM YIEEQDDQDG SSWKCIVRNR
210 220 230 240 250
NELAETLALL KAQIDPVLLK NSSQQEDSSR ESPTLEDEET KKDEETPKQE
260 270 280 290 300
ASKENEKTGA DERSVDSGKC SAASALEEPA VKTEKADEKE LAKLPVIVKL
310 320 330 340 350
EKPLPETEEK KIIREESDSF KENVKPIKVE AKECRADPKD LKGSLERLGS
360 370 380 390 400
QEPERADFGS NIKSQDIIEK STEETEKLKN DQQAKIPLKK REIKLSDDFD
410 420 430 440 450
SPVKGPLCKS ATPTKEVLKD DIKQEEETCK RVSTISALSH EGKQLVNGEI
460 470 480 490 500
NDDKVIPNFK TEQMEIQLCD TKEDSASIPA KDGNACMEGN GTECLNSVIT
510 520 530 540 550
STKTSELEKE APLGKGIDSS VPDIESLSQK ARLEEPGLLN MDMPLEPSEK
560 570 580 590 600
ATDLSLKPTL SATEPCSTKV EEKAPRSKSE NHTPGIECLE RVEKAKKTSI
610 620 630 640 650
DKDIQKLSPI PEEVVRGALE SEKSGPCEVA ETPLPLSMAG AKEKQTSEKK
660 670 680 690 700
DVDCSRGSSE SQSLENASPE ILKEDSESSR EEVAKLDNAQ TSGMEDTSET
710 720 730 740 750
KGSVQKNKFK YKLVSERNST ASENTEITSE RKKEGIKLTI RISSRKKKPD
760 770 780 790 800
CPPQTVDSES KEEKAGKEEE KASVGRTLRR SPRISRPTAK VAEIRVQKAD
810 820 830 840 850
KRRADGEDGV EGEPASLQTA DKKDHLKKAE KDTNSKASKV KPKGKVRWTG
860 870 880 890 900
SRTRGRWKYS SNDESEGSES DKSSAALEEE EGKEGEEAVL PDDDEPCKKC
910 920 930 940 950
GLPNHPELIL LCDSCDSGYH TACLRPPLMI IPDGEWFCPP CQHKLLCEKL
960 970 980 990 1000
EEQLQDLDVA LKKKERAERR KERLVYVGIS IENIIPPQEP EFSEEQEEKK
1010 1020 1030 1040 1050
KDAKKSKANA LERRSTRTRK CISYRFDEFD EAIDEAIEDD IKEADGGGVG
1060 1070 1080 1090 1100
RGKDISTITG HRGKDISTIL DEERKENKRP QRAAAARRKK RRRLNDLDSD
1110 1120 1130 1140 1150
SNLDEEESED EFKISDGSQD EFVVSDENPD ESEEEPPSNE DSDTDFCSRR
1160 1170 1180 1190 1200
LRRHPSRPMR QSRRLRRKTP KKKYSDDDEE EEESEENSRD SESDFSDDFS
1210 1220 1230 1240 1250
DDFVETRRRR SRRNQKRQIN YKEDSESDGS QKSLRRGKEI RRVHKRRLSS
1260 1270 1280 1290 1300
SESEESFMSK NSEDDELTKE SKRSVRKRGR STDDYSEADE DDEEEGKPSR
1310 1320 1330 1340 1350
KRLHRIETDE ESCDNAHGDA DQPARDSQPS ALPSEQESSK KPYRIESDEE
1360 1370 1380 1390 1400
EDFENKVGSP LDYSLVDLPS TNGQSPGKAI ENLMGKATEK SQTPKDNGTA
1410 1420 1430 1440
SASLAPNGTS GGQEVGAPEE DEDELLRVTD LVDYVCNSEQ L
Length:1,441
Mass (Da):161,750
Last modified:February 17, 2016 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6F5B28E3B7976E9A
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0U1RP31A0A0U1RP31_MOUSE
Remodeling and spacing factor 1
Rsf1
121Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0U1RPA7A0A0U1RPA7_MOUSE
Remodeling and spacing factor 1
Rsf1
109Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0U1RNQ5A0A0U1RNQ5_MOUSE
Remodeling and spacing factor 1
Rsf1
14Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC124541 Genomic DNA No translation available.
AC149605 Genomic DNA No translation available.
AC151477 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
NP_001074736.1, NM_001081267.2

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Mm.43977
Mm.479833

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000107153; ENSMUSP00000102771; ENSMUSG00000035623

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
233532

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:233532

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124541 Genomic DNA No translation available.
AC149605 Genomic DNA No translation available.
AC151477 Genomic DNA No translation available.
RefSeqiNP_001074736.1, NM_001081267.2
UniGeneiMm.43977
Mm.479833

3D structure databases

ProteinModelPortaliE9PWW9
SMRiE9PWW9
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

ComplexPortaliCPX-463 RSF complex
STRINGi10090.ENSMUSP00000037409

Proteomic databases

jPOSTiE9PWW9
PaxDbiE9PWW9
PeptideAtlasiE9PWW9
PRIDEiE9PWW9

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000107153; ENSMUSP00000102771; ENSMUSG00000035623
GeneIDi233532
KEGGimmu:233532

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
51773
MGIiMGI:2682305 Rsf1

Phylogenomic databases

eggNOGiENOG410IFYI Eukaryota
ENOG410YTDT LUCA
GeneTreeiENSGT00530000064411
KOiK11657
OMAiRQINYKE
OrthoDBi917466at2759

Miscellaneous databases

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000035623 Expressed in 249 organ(s), highest expression level in manus
ExpressionAtlasiE9PWW9 baseline and differential

Family and domain databases

Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR028938 Rsf-1
IPR028942 WHIM1_dom
IPR019786 Zinc_finger_PHD-type_CS
IPR011011 Znf_FYVE_PHD
IPR001965 Znf_PHD
IPR019787 Znf_PHD-finger
IPR013083 Znf_RING/FYVE/PHD
PANTHERiPTHR10615:SF156 PTHR10615:SF156, 1 hit
PfamiView protein in Pfam
PF00628 PHD, 1 hit
PF15612 WHIM1, 1 hit
SMARTiView protein in SMART
SM00249 PHD, 1 hit
SUPFAMiSSF57903 SSF57903, 1 hit
PROSITEiView protein in PROSITE
PS01359 ZF_PHD_1, 1 hit
PS50016 ZF_PHD_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiE9PWW9_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E9PWW9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: February 17, 2016
Last modified: January 16, 2019
This is version 66 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health

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