UniProtKB - E9PWW6 (E9PWW6_MOUSE)
Protein
Submitted name:
Zinc finger CCCH type-containing 7 A
Gene
Zc3h7a
Organism
Mus musculus (Mouse)
Status
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 633 – 655 | C3H1-typePROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 768 – 796 | C3H1-typePROSITE-ProRule annotationAdd BLAST | 29 | |
Zinc fingeri | 905 – 927 | C3H1-typePROSITE-ProRule annotationAdd BLAST | 23 |
GO - Molecular functioni
- metal ion binding Source: UniProtKB-KW
- miRNA binding Source: MGI
GO - Biological processi
- posttranscriptional regulation of gene expression Source: MGI
- production of miRNAs involved in gene silencing by miRNA Source: MGI
Keywordsi
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: Zinc finger CCCH type-containing 7 AImported |
Gene namesi | Name:Zc3h7aImported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:2445044, Zc3h7a |
PTM / Processingi
Proteomic databases
EPDi | E9PWW6 |
MaxQBi | E9PWW6 |
PaxDbi | E9PWW6 |
PeptideAtlasi | E9PWW6 |
PRIDEi | E9PWW6 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000037965, Expressed in female gonad and 241 other tissues |
ExpressionAtlasi | E9PWW6, baseline and differential |
Interactioni
Protein-protein interaction databases
STRINGi | 10090.ENSMUSP00000041308 |
Miscellaneous databases
RNActi | E9PWW6, protein |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 633 – 655 | C3H1-typeInterPro annotationAdd BLAST | 23 | |
Domaini | 768 – 796 | C3H1-typeInterPro annotationAdd BLAST | 29 | |
Domaini | 905 – 927 | C3H1-typeInterPro annotationAdd BLAST | 23 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 929 – 949 | Sequence analysisAdd BLAST | 21 |
Zinc finger
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 633 – 655 | C3H1-typePROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 768 – 796 | C3H1-typePROSITE-ProRule annotationAdd BLAST | 29 | |
Zinc fingeri | 905 – 927 | C3H1-typePROSITE-ProRule annotationAdd BLAST | 23 |
Keywords - Domaini
Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotationARBA annotationPhylogenomic databases
eggNOGi | ENOG502QSHP, Eukaryota |
GeneTreei | ENSGT00390000018542 |
HOGENOMi | CLU_012672_0_0_1 |
InParanoidi | E9PWW6 |
TreeFami | TF329017 |
Family and domain databases
Gene3Di | 1.25.40.10, 1 hit |
InterProi | View protein in InterPro IPR011990, TPR-like_helical_dom_sf IPR019734, TPR_repeat IPR039691, ZC3H7A/B IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type IPR000571, Znf_CCCH IPR036855, Znf_CCCH_sf |
PANTHERi | PTHR14928, PTHR14928, 1 hit |
SMARTi | View protein in SMART SM00028, TPR, 2 hits SM00356, ZnF_C3H1, 3 hits |
SUPFAMi | SSF48452, SSF48452, 1 hit SSF57667, SSF57667, 1 hit SSF90229, SSF90229, 1 hit |
PROSITEi | View protein in PROSITE PS50103, ZF_C3H1, 3 hits PS00028, ZINC_FINGER_C2H2_1, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All
E9PWW6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSSVSEERRK RQHSIKEGLQ FIQPPLSYPG TQEQYAVYLH ALVRNLFNEG
60 70 80 90 100
NDIYRECDWR GSLIQYSEAL SIANYAKSEE ILIPTEIIEK LRINRIACYS
110 120 130 140 150
NMGLRDEVLE DCNAVLSVNA SNCKALYRKA KALSDLGHYR EAYDAVAKCS
160 170 180 190 200
LAVPQDEHVI KLTQELAQKL GFKIRKAYVR AEHLLKAVPG DGAPKAVNYS
210 220 230 240 250
VEDIEPDLLA PRQEALSVAS LPTSSFSHVI GSELASVPIM PVTSVLQLQV
260 270 280 290 300
DESPLPSTVF ANGGKIPFTI SDAFLDDDIV LGDEIDALLD SAPETNDAVM
310 320 330 340 350
SSTLVRGPLP TASAAPSLPF RTQSLLGTLP MGTRYPEPSF ADFFPPLTSS
360 370 380 390 400
LEEFYSSLNS FSVTESKRDL CTSTAREGTP LNNSNSSLLL MNGPGNLLAS
410 420 430 440 450
ENFLGITSQP RNDFGNFFGS VIAKPFSSGT PRHPLEGTHE LRQACQICFV
460 470 480 490 500
KSGPKLMDFT YHANVDHKCK KDILIGRIKN VEDKSWKKIR PRPTKTNYEG
510 520 530 540 550
PYYICKDVAA DDECRYPGHC TFAYCQEEID VWTLERKGAF SREAFFGGNG
560 570 580 590 600
KINLTVVRIL QEHHGEFTFL CEKCFDHKPR MISKRNKDNS TACSHPVTKH
610 620 630 640 650
EFEDNKCLVH ILRETTVKYS KIRSFHKQCQ FDICRHEVRY GCVREDECFY
660 670 680 690 700
AHSLIELKVW IMQSERGISH DDIAQQSKQY WRSLQASMPG VQVLGNQIMP
710 720 730 740 750
GLLNMEIKFV CAQCLRNGQV IEPDRNRKYC SAKAQHSWTK ERRAMRAMSF
760 770 780 790 800
ERKKWMNIRP LPTKKQMPLQ FDLCNHIANR KKCQYVGNCS FAHSPEEREV
810 820 830 840 850
WTYMKDNKIH DIEQFYELWL KNQKTEKSDE TASHCSKENG KQIHMPTDYA
860 870 880 890 900
EVTVDFHCWM CGKNCNSEKQ WQDHISSEKH KEKVFHTEDD QYCWQHRFPT
910 920 930 940 950
GYFSICERYI NGSCTEGSSC KFAHGNAELH EWEERRKALQ MKFKKARKDH
960 970
LIAPNDNDFG KYSFLFKDLK
Computationally mapped potential isoform sequencesi
There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketE9Q8M5 | E9Q8M5_MOUSE | Zinc finger CCCH type-containing 7 ... | Zc3h7a | 762 | Annotation score: | ||
F6X2N3 | F6X2N3_MOUSE | Zinc finger CCCH type-containing 7 ... | Zc3h7a | 174 | Annotation score: | ||
D3YZY2 | D3YZY2_MOUSE | Zinc finger CCCH type-containing 7 ... | Zc3h7a | 206 | Annotation score: | ||
D6RI42 | D6RI42_MOUSE | Zinc finger CCCH type-containing 7 ... | Zc3h7a | 390 | Annotation score: | ||
E9Q0D3 | E9Q0D3_MOUSE | Zinc finger CCCH type-containing 7 ... | Zc3h7a | 583 | Annotation score: | ||
D3YVH9 | D3YVH9_MOUSE | Zinc finger CCCH type-containing 7 ... | Zc3h7a | 84 | Annotation score: | ||
D3Z5I3 | D3Z5I3_MOUSE | Zinc finger CCCH type-containing 7 ... | Zc3h7a | 87 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC087541 Genomic DNA No translation available. |
RefSeqi | XP_006521727.1, XM_006521664.2 XP_006521728.1, XM_006521665.2 XP_006521729.1, XM_006521666.1 |
Genome annotation databases
Ensembli | ENSMUST00000037633; ENSMUSP00000041308; ENSMUSG00000037965 |
GeneIDi | 106205 |
UCSCi | uc033gxp.1, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC087541 Genomic DNA No translation available. |
RefSeqi | XP_006521727.1, XM_006521664.2 XP_006521728.1, XM_006521665.2 XP_006521729.1, XM_006521666.1 |
3D structure databases
SMRi | E9PWW6 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 10090.ENSMUSP00000041308 |
Proteomic databases
EPDi | E9PWW6 |
MaxQBi | E9PWW6 |
PaxDbi | E9PWW6 |
PeptideAtlasi | E9PWW6 |
PRIDEi | E9PWW6 |
Protocols and materials databases
Antibodypediai | 24731, 126 antibodies |
Genome annotation databases
Ensembli | ENSMUST00000037633; ENSMUSP00000041308; ENSMUSG00000037965 |
GeneIDi | 106205 |
UCSCi | uc033gxp.1, mouse |
Organism-specific databases
CTDi | 29066 |
MGIi | MGI:2445044, Zc3h7a |
Phylogenomic databases
eggNOGi | ENOG502QSHP, Eukaryota |
GeneTreei | ENSGT00390000018542 |
HOGENOMi | CLU_012672_0_0_1 |
InParanoidi | E9PWW6 |
TreeFami | TF329017 |
Miscellaneous databases
BioGRID-ORCSi | 106205, 3 hits in 17 CRISPR screens |
ChiTaRSi | Zc3h7a, mouse |
RNActi | E9PWW6, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000037965, Expressed in female gonad and 241 other tissues |
ExpressionAtlasi | E9PWW6, baseline and differential |
Family and domain databases
Gene3Di | 1.25.40.10, 1 hit |
InterProi | View protein in InterPro IPR011990, TPR-like_helical_dom_sf IPR019734, TPR_repeat IPR039691, ZC3H7A/B IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type IPR000571, Znf_CCCH IPR036855, Znf_CCCH_sf |
PANTHERi | PTHR14928, PTHR14928, 1 hit |
SMARTi | View protein in SMART SM00028, TPR, 2 hits SM00356, ZnF_C3H1, 3 hits |
SUPFAMi | SSF48452, SSF48452, 1 hit SSF57667, SSF57667, 1 hit SSF90229, SSF90229, 1 hit |
PROSITEi | View protein in PROSITE PS50103, ZF_C3H1, 3 hits PS00028, ZINC_FINGER_C2H2_1, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | E9PWW6_MOUSE | |
Accessioni | E9PWW6Primary (citable) accession number: E9PWW6 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 5, 2011 |
Last sequence update: | April 5, 2011 | |
Last modified: | December 2, 2020 | |
This is version 71 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |