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Protein
Submitted name:

Olfactory receptor 218

Gene

Olfr218

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorSAAS annotation, Receptor, Transducer
Biological processOlfactionSAAS annotation, Sensory transduction

Enzyme and pathway databases

ReactomeiR-MMU-381753 Olfactory Signaling Pathway

Names & Taxonomyi

Protein namesi
Submitted name:
Olfactory receptor 218Imported
Submitted name:
Olfr218Imported
Gene namesi
Name:Olfr218Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 1

Organism-specific databases

MGIiMGI:3030052 Olfr218

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei26 – 49HelicalSequence analysisAdd BLAST24
Transmembranei61 – 82HelicalSequence analysisAdd BLAST22
Transmembranei102 – 121HelicalSequence analysisAdd BLAST20
Transmembranei141 – 159HelicalSequence analysisAdd BLAST19
Transmembranei201 – 227HelicalSequence analysisAdd BLAST27
Transmembranei239 – 261HelicalSequence analysisAdd BLAST23
Transmembranei273 – 293HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000046643 Expressed in 2 organ(s), highest expression level in brown adipose tissue

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000053317

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini42 – 291G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST250

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiENOG410IJU6 Eukaryota
ENOG41113GG LUCA
GeneTreeiENSGT00760000119043
InParanoidiE9PWV2
KOiK04257
OMAiSMAIVQV
OrthoDBiEOG091G0AZH
TreeFamiTF337624

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR000725 Olfact_rcpt
PfamiView protein in Pfam
PF13853 7tm_4, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PR00245 OLFACTORYR
PROSITEiView protein in PROSITE
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequencei

Sequence statusi: Complete.

E9PWV2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPKKNSTVVA EFLFEGFSSF DWQHRLGFFI VFLTLYLLTL SGNMIIVTII
60 70 80 90 100
RLDRHLHTPM YFFLSMLSIS ETFYTIAIIP RMLAGLLNPY QAIDIQGCAT
110 120 130 140 150
QLFFYLTFGI NNCFLLTAMG YDRYVAICNP LRYSVIMGKK ACILLASGSL
160 170 180 190 200
GIGLSMAIVQ VTSVFGLPFC DGFVIAHFFC DVRPLLKLAC TDTTINEIIN
210 220 230 240 250
FIVSVCVLVL PMSLVFISYV VIISTILKIA SAEGRKKAFA TCASHLTVVI
260 270 280 290 300
IHYGCASIIY LKPKSQTSLG QDRLISVTYT VITPLLNPVV YSLRNKEVKE
310
ALRKAIGRRP LSS
Length:313
Mass (Da):34,867
Last modified:April 5, 2011 - v1
Checksum:i07850755229E8578
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC125268 Genomic DNA No translation available.
KP290798 Genomic DNA Translation: ALI87955.1
RefSeqiNP_001001809.2, NM_001001809.2
UniGeneiMm.377732

Genome annotation databases

EnsembliENSMUST00000057548; ENSMUSP00000053317; ENSMUSG00000046643
ENSMUST00000215844; ENSMUSP00000149832; ENSMUSG00000046643
ENSMUST00000216603; ENSMUSP00000150815; ENSMUSG00000046643
GeneIDi258880
KEGGimmu:258880
UCSCiuc007drc.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC125268 Genomic DNA No translation available.
KP290798 Genomic DNA Translation: ALI87955.1
RefSeqiNP_001001809.2, NM_001001809.2
UniGeneiMm.377732

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000053317

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000057548; ENSMUSP00000053317; ENSMUSG00000046643
ENSMUST00000215844; ENSMUSP00000149832; ENSMUSG00000046643
ENSMUST00000216603; ENSMUSP00000150815; ENSMUSG00000046643
GeneIDi258880
KEGGimmu:258880
UCSCiuc007drc.1 mouse

Organism-specific databases

CTDi258880
MGIiMGI:3030052 Olfr218

Phylogenomic databases

eggNOGiENOG410IJU6 Eukaryota
ENOG41113GG LUCA
GeneTreeiENSGT00760000119043
InParanoidiE9PWV2
KOiK04257
OMAiSMAIVQV
OrthoDBiEOG091G0AZH
TreeFamiTF337624

Enzyme and pathway databases

ReactomeiR-MMU-381753 Olfactory Signaling Pathway

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000046643 Expressed in 2 organ(s), highest expression level in brown adipose tissue

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR000725 Olfact_rcpt
PfamiView protein in Pfam
PF13853 7tm_4, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PR00245 OLFACTORYR
PROSITEiView protein in PROSITE
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE9PWV2_MOUSE
AccessioniPrimary (citable) accession number: E9PWV2
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: November 7, 2018
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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