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Entry version 64 (31 Jul 2019)
Sequence version 1 (05 Apr 2011)
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Protein
Submitted name:

Transformation/transcription domain-associated protein

Gene

Trrap

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionKinasePROSITE-ProRule annotation, Transferase

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Transformation/transcription domain-associated proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TrrapImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2153272 Trrap

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
E9PWT1

MaxQB - The MaxQuant DataBase

More...
MaxQBi
E9PWT1

PeptideAtlas

More...
PeptideAtlasi
E9PWT1

PRoteomics IDEntifications database

More...
PRIDEi
E9PWT1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000045482 Expressed in 271 organ(s), highest expression level in dorsal pancreas

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
E9PWT1 baseline and differential

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini2703 – 3274FATInterPro annotationAdd BLAST572
Domaini3527 – 3738PI3K/PI4KInterPro annotationAdd BLAST212
Domaini3826 – 3858FATCInterPro annotationAdd BLAST33

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni489 – 542DisorderedSequence analysisAdd BLAST54
Regioni2542 – 2577DisorderedSequence analysisAdd BLAST36

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili2785 – 2809Sequence analysisAdd BLAST25

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi489 – 526Pro-richSequence analysisAdd BLAST38

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the PI3/PI4-kinase family.SAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0889 Eukaryota
COG5032 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000017961

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016024 ARM-type_fold
IPR003152 FATC_dom
IPR011009 Kinase-like_dom_sf
IPR000403 PI3/4_kinase_cat_dom
IPR003151 PIK-rel_kinase_FAT
IPR014009 PIK_FAT
IPR033317 TRA1/TRRAP

The PANTHER Classification System

More...
PANTHERi
PTHR11139:SF1 PTHR11139:SF1, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02259 FAT, 1 hit
PF00454 PI3_PI4_kinase, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01343 FATC, 1 hit
SM00146 PI3Kc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371 SSF48371, 3 hits
SSF56112 SSF56112, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51189 FAT, 1 hit
PS51190 FATC, 1 hit
PS50290 PI3_4_KINASE_3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

E9PWT1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAFVATQGAT VVDQTTLMKK YLQFVAALTD VNTPDETKLK MMQEVSENFE
60 70 80 90 100
NVTSSPQYST FLEHIIPRFL TFLQDGEVQF LQEKPAQQLR KLVLEILHRI
110 120 130 140 150
PTNEHLRPHT KNVLSVMFRF LETENEENVL ICLRIIIELH KQFRPPITQE
160 170 180 190 200
IHHFLDFVKQ IYKELPKVVN RYFENPQGIP ENTVPPPEMV GMITTVAVKV
210 220 230 240 250
NPEREDSETR THSIIPRGSL SLKVLAELPI IVVLMYQLYK LNIHNVVAEF
260 270 280 290 300
VPLIMNTIAI QVSTQARQHK LYNKELYADF IAAQIKTLSF LAYIIRIYQE
310 320 330 340 350
LVTKYSQQMV KGMLQLLSNC PAETAHLRKE LLIAAKHILT TELRNQFIPC
360 370 380 390 400
MDKLFDESIL IGSGYTARET LRPLAYSTLA DLVHHVRQHL PLSDLSLAVQ
410 420 430 440 450
LFAKNIDDES LPSSIQTMSC KLLLNLVDCI RSKSEQESGN GRDVLMRMLE
460 470 480 490 500
VFVLKFHTIA RYQLSAIFKK CKPQSELGAA EAALPGVPTA PAAPGPAPSP
510 520 530 540 550
APVPAPAPPP PPPPAPATPV TPAPVPPFEK QGEKDKEDKQ TFQVTDCRSL
560 570 580 590 600
VKTLVCGVKT ITWGITSCKA PGAQFIPNKQ LQPKETQIYI KLVKYAMQAL
610 620 630 640 650
DIYQVQIAGN GQTYIRVANC QTVRMKEEKE VLEHFAGVFT MMNPLTFKEI
660 670 680 690 700
FQTTVPYMVE RISKNYALQI VANSFLANPT TSALFATILV EYLLERLPEM
710 720 730 740 750
GSNVELSNLY LKLFKLVFGS VSLFAAENEQ MLKPHLHKIV NSSMELAQTA
760 770 780 790 800
KEPYNYFLLL RALFRSIGGG SHDLLYQEFL PLLPNLLQGL NMLQSGLHKQ
810 820 830 840 850
HMKDLFVELC LTVPVRLSSL LPYLPMLMDP LVSALNGSQT LVSQGLRTLE
860 870 880 890 900
LCVDNLQPDF LYDHIQPVRA ELMQALWRTL RNPADSISHV AYRVLGKFGG
910 920 930 940 950
SNRKMLKESQ KLHYVVTEVQ GPSITVEFSD CKASLQLPME KAIETALDCL
960 970 980 990 1000
KSANTEPYYR RQAWEVIRCF LVAMMSLEDN KHALYQLLAH PNFTEKTIPN
1010 1020 1030 1040 1050
VIISHRYKAQ DTPARKTFEQ ALTGAFMSAV IKDLRPSALP FVASLIRHYT
1060 1070 1080 1090 1100
MVAVAQQCGP FLLPCYQVGS QPSTAMFHSE ENGSKGMDPL VLIDAIAICM
1110 1120 1130 1140 1150
AYEEKELCKI GEVALAVIFD VASIILGSKE RACQLPLFSY IVERLCACCY
1160 1170 1180 1190 1200
EQAWYAKLGG VVSIKFLMER LPLTWVLQNQ QTFLKALLFV MMDLTGEVSN
1210 1220 1230 1240 1250
GAVAMAKTTL EQLLMRCATP LKDEERAEEI VLAQEKSFHH VTHDLVREVT
1260 1270 1280 1290 1300
SPNSTVRKQA MHSLQVLAQV TGKSVTVIME PHKEVLQDMV PPKKHLLRHQ
1310 1320 1330 1340 1350
PANAQIGLME GNTFCTTLQP RLFTMDLNVV EHKVFYTELL NLCEAEDSAL
1360 1370 1380 1390 1400
TKLPCYKSLP SLVPLRIAAL NALAACNYLP QSREKIIAAL FKALNSTNSE
1410 1420 1430 1440 1450
LQEAGEACMR KFLEGATIEV DQIHTHMRPL LMMLGDYRSL TLNVVNRLTS
1460 1470 1480 1490 1500
VTRLFPNSFN DKFCDQMMQH LRKWMEVVVI THKGGQRSDG NESLSECGRC
1510 1520 1530 1540 1550
SLSPFCQFEE MKICSAIINL FHLIPAAPQT LVKPLLEVVM KTERAMLIEA
1560 1570 1580 1590 1600
GSPFREPLIK FLTRHPSQTV ELFMMEATLN DPQWSRMFMS FLKHKDARPL
1610 1620 1630 1640 1650
RDVLAANPNR FITLLLPGGA QTAVRPGSPS TSNMRLDLQF QAIKIISIIV
1660 1670 1680 1690 1700
KNDDAWLASQ HSLVSQLRRV WVSETFQERH RKENMAATNW KEPKLLAFCL
1710 1720 1730 1740 1750
LNYCKRNYGD IELLFQLLRA FTGRFLCNMT FLKEYMEEEI PKNYSIAQKR
1760 1770 1780 1790 1800
ALFFRFVEFN DPNFGDELKA KVLQHILNPA FLYSFEKGEG EQLLGPPNPE
1810 1820 1830 1840 1850
GDNPESITSV FITKVLDPEK QADMLDSLRI YLLQYATLLV EHAPHHIHDN
1860 1870 1880 1890 1900
NKNRNSKLRR LMTFAWPCLL SKACVDPACK YSGHLLLAHI IAKFAIHKKI
1910 1920 1930 1940 1950
VLQVFHSLLK AHAMEARAIV RQAMAILTPA VPARMEDGHQ MLTHWTRKII
1960 1970 1980 1990 2000
VEEGHTVPQL VHILHLIVQH FKVYYPVRHH LVQHMVSAMQ RLGFTPSVTI
2010 2020 2030 2040 2050
EQRRLAVDLS EVVIKWELQR IKDQQPDSDM DPNSSGEGVN SVSIKRGLSV
2060 2070 2080 2090 2100
DSAQEVKRFR AATGAISAVF GRSQSLPGAD SLLAKPIDKQ HTDTVVNFLI
2110 2120 2130 2140 2150
RVACQVNDNT NTAGSPGEVL SRRCVNLLKT ALRPDMWCKS ELKLQWFDKL
2160 2170 2180 2190 2200
LMTVEQPNQV NYGNICTGLE VLNFLLTVLQ SPAILSSFKP LQRGIAACMT
2210 2220 2230 2240 2250
CGNTKVLRAV HSLLSRLMSI FPTEPSTSSV ASKYEELECL YAAVGKVIYE
2260 2270 2280 2290 2300
GLTNYEKATS ANPSQLFGTL MILKSACCNN PSYIDRLISV FMRSLQKMVR
2310 2320 2330 2340 2350
EHLNPQTASG STEATAAGTS ELVMLSLDLV KTRLAVMSME MRKNFIQTIL
2360 2370 2380 2390 2400
TSLIEKSPDA KILRAVVKIV EEWVKNNSPM AANQTPTLRE KSILLVKMMT
2410 2420 2430 2440 2450
YIEKRFPEDL ELNAQFLDLV NYVYRDEALS GSELTAKLEP AFLSGLRCAQ
2460 2470 2480 2490 2500
PLIRAKFFEV FDNSMKRRVY ERLLYVTCSQ NWEAMGSHFW IKQCIELLLA
2510 2520 2530 2540 2550
VCEKSTAIGT SCQGAMLPSI TNVINLADSH DRAAFAMVTH VKQEPREREN
2560 2570 2580 2590 2600
SESKEEDVEI DIELAPGDQT STPKTKELSE KDIGNQLHML TNRHDKFLDT
2610 2620 2630 2640 2650
LREVKTGALL SAFVQLCHIS TTLAEKTWVQ LFPRLWKILS DRQQHALAGE
2660 2670 2680 2690 2700
ISPFLCSGSH QVQRDCQPSA LNCFVEAMSQ CVPPIPMRPC VLKYLGKTHN
2710 2720 2730 2740 2750
LWFRSTLMLE HQAFEKGLSL PIKPKQTTEF YEQESITPPQ QEILDSLAEL
2760 2770 2780 2790 2800
YSLLQEEDMW AGLWQKRCKF SETATAIAYE QHGFFEQAQE SYEKAMDKAK
2810 2820 2830 2840 2850
KEHERSNASP AIFPEYQLWE DHWIRCSKEL NQWEALTEFG QSKGHINPYL
2860 2870 2880 2890 2900
VLECAWRVSN WTAMKEALVQ VEVSCPKEMA WKVNMYRGYL AICHPEEQQL
2910 2920 2930 2940 2950
SFIERLVEMA SSLAIREWRR LPHVVSHVHT PLLQAAQQII ELQEAAQINA
2960 2970 2980 2990 3000
GLQPTNLGRN NSLHDMKTVV KTWRNRLPIV SDDLSHWSSV FMWRQHHYQG
3010 3020 3030 3040 3050
KPTWSGMHSS SIVTAYENSS HHDPSSNNAM LGVHASASAI IQYGKIARKQ
3060 3070 3080 3090 3100
GLVNVALDIL SRIHTIPTVP IVDCFQKIRQ QVKCYLQLAG VMGKNECMQG
3110 3120 3130 3140 3150
LEVIESTNLK YFTKEMTAEF YALKGMFLAQ INKSEEANKA FSAAVQMHDV
3160 3170 3180 3190 3200
LVKAWAMWGD YLESIFVKER QLHLGVSAIT CYLHACRHQN ESKSRKYLAK
3210 3220 3230 3240 3250
VLWLLSFDDD KNTLADAVDK YCIGVPPIQW LAWIPQLLTC LVGSEGKLLL
3260 3270 3280 3290 3300
NLISQVGRVY PQAVYFPIRT LYLTLKIEQR ERYKSDPGPI RATAPMWRCS
3310 3320 3330 3340 3350
RIMHMQRELH PTLLSSLEGI VDQMVWFREN WHEEVLRQLQ QGLAKCYSVA
3360 3370 3380 3390 3400
FEKSGAVSDA KITPHTLNFV KKLVSTFGVG LENVSNVSTM FSSAASESLA
3410 3420 3430 3440 3450
RRAQATAQDP VFQKLKGQFT TDFDFSVPGS MKLHNLISKL KKWIKILEAK
3460 3470 3480 3490 3500
TKQLPKFFLI EEKCRFLSNF SAQTAEVEIP GEFLMPKPTH YYIKIARFMP
3510 3520 3530 3540 3550
RVEIVQKHNT AARRLHIRGH NGKIYPYLVM NDACLTESRR EERVLQLLRL
3560 3570 3580 3590 3600
LNPCLEKRKE TTKRHLFFTV PRVVAVSPQM RLVEDNPSSL SLVEIYKQRC
3610 3620 3630 3640 3650
AKKGIEHDNP ISRYYDRLAT VQARGTQASH QVLRDILKEV QSNMVPRSML
3660 3670 3680 3690 3700
KEWALHTFPN ATDYWTFRKM FTIQLALIGF AEFVLHLNRL NPEMLQIAQD
3710 3720 3730 3740 3750
TGKLNVAYFR FDINDATGDL DANRPVPFRL TPNISEFLTT IGVSGPLTAS
3760 3770 3780 3790 3800
MIAVARCFAQ PNFKVDGVLK TVLRDEIIAW HKKTQEDTSS PLSAAGQPEN
3810 3820 3830 3840 3850
MDSQQLVSLV QKAVTAIMTR LHNLAQFDGG ESKVNTLVAA ANSLDNLCRM

DPAWHPWL
Length:3,858
Mass (Da):437,223
Last modified:April 5, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB384575CDD10E45E
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q80YV3TRRAP_MOUSE
Transformation/transcription domain...
Trrap
2,565Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9QLK7E9QLK7_MOUSE
Transformation/transcription domain...
Trrap
3,847Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PZA7E9PZA7_MOUSE
Transformation/transcription domain...
Trrap
3,829Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F7CGG2F7CGG2_MOUSE
Transformation/transcription domain...
Trrap
3,587Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1D5RLL4A0A1D5RLL4_MOUSE
Transformation/transcription domain...
Trrap
3,859Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D3YY11D3YY11_MOUSE
Transformation/transcription domain...
Trrap
58Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC113295 Genomic DNA No translation available.
AC131728 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000094120; ENSMUSP00000091668; ENSMUSG00000045482

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC113295 Genomic DNA No translation available.
AC131728 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Proteomic databases

EPDiE9PWT1
MaxQBiE9PWT1
PeptideAtlasiE9PWT1
PRIDEiE9PWT1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000094120; ENSMUSP00000091668; ENSMUSG00000045482

Organism-specific databases

MGIiMGI:2153272 Trrap

Phylogenomic databases

eggNOGiKOG0889 Eukaryota
COG5032 LUCA
GeneTreeiENSGT00390000017961

Miscellaneous databases

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSMUSG00000045482 Expressed in 271 organ(s), highest expression level in dorsal pancreas
ExpressionAtlasiE9PWT1 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR003152 FATC_dom
IPR011009 Kinase-like_dom_sf
IPR000403 PI3/4_kinase_cat_dom
IPR003151 PIK-rel_kinase_FAT
IPR014009 PIK_FAT
IPR033317 TRA1/TRRAP
PANTHERiPTHR11139:SF1 PTHR11139:SF1, 1 hit
PfamiView protein in Pfam
PF02259 FAT, 1 hit
PF00454 PI3_PI4_kinase, 1 hit
SMARTiView protein in SMART
SM01343 FATC, 1 hit
SM00146 PI3Kc, 1 hit
SUPFAMiSSF48371 SSF48371, 3 hits
SSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS51189 FAT, 1 hit
PS51190 FATC, 1 hit
PS50290 PI3_4_KINASE_3, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiE9PWT1_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E9PWT1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: July 31, 2019
This is version 64 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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