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Protein
Submitted name:

Armadillo repeat-containing, X-linked 4

Gene

Armcx4

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Armadillo repeat-containing, X-linked 4Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Armcx4Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2147887 Armcx4

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
E9PWM3

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
E9PWM3

PeptideAtlas

More...
PeptideAtlasi
E9PWM3

PRoteomics IDEntifications database

More...
PRIDEi
E9PWM3

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
E9PWM3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
E9PWM3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000049804 Expressed in 241 organ(s), highest expression level in humerus cartilage element

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
E9PWM3 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
E9PWM3, 1 interactor

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000132914

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini2096 – 2349Arm_2InterPro annotationAdd BLAST254
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati2149 – 2186ARMPROSITE-ProRule annotationAdd BLAST38

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410JB0F Eukaryota
ENOG4111A6X LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000162587

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
E9PWM3

Identification of Orthologs from Complete Genome Data

More...
OMAi
VSIGYWT

Database of Orthologous Groups

More...
OrthoDBi
EOG091G0PCU

TreeFam database of animal gene trees

More...
TreeFami
TF335652

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR006911 ARM-rpt_dom
IPR016024 ARM-type_fold
IPR000225 Armadillo

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF04826 Arm_2, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371 SSF48371, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50176 ARM_REPEAT, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

E9PWM3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGRVQDVGWA TAGLVIWAGT CYCIYRLTKG RTQSVSGHAR NGSRIETETV
60 70 80 90 100
VGEQNQTLAT SEAMAGREAE TRVKTEPETG EGGEPVAEVD SKVPVLVRSS
110 120 130 140 150
GNCQAKTMLE EEIETQSETS SLVETMVMTE AVTLTESTSQ AKEVTMKEAV
160 170 180 190 200
TQTDAEAEAV GKKEAVTQTK AKAWAMAGRA EVKKEAMTQT KAEARTLAEK
210 220 230 240 250
ETEINRVTVT QSEVLAVTKE VVKIGTMNET GVVAEAMIRP LEETVSVTRT
260 270 280 290 300
QSEARLDAAV DTKENLNDMS VVVTGVDTKS CAQSQAVAII QNDDMAGAEA
310 320 330 340 350
DKEDLKNMSK AGSGIDMKVP GQPHIAANNL AEAVPGAKND AWDNAKDICE
360 370 380 390 400
AEADIRTCLI QSETVAKIET EATSSATMDG GKDANAKAMT DVNVTDTQPQ
410 420 430 440 450
AVTSDQTEAM PDAKVKGKGN ASAMAKAGAK ANTKTSSQTD ALPDAGDKNR
460 470 480 490 500
SDNNVTAKAE TGIDMVSCTQ TEPVAKDNAN TTSKEGAQAT GQSQGEALPN
510 520 530 540 550
TKGKARGKAK AKCKAAAGTD TKTCAQPQAG TKTQAEALSD SKVDSKSDSN
560 570 580 590 600
GVSKAGAKAD QKASGQPQPV ANCQNEALPG TKNKVKGNPN PTPKTEAGTA
610 620 630 640 650
TTSSAQTNVT SSQGETTPGA KNKAKGNRNS VPKAGAGPDT TGSAQSQTVA
660 670 680 690 700
NSHSEALPGA KNKVKSNSNV VPKAEAGVGA CPQSVPASQG TALTGTKTKV
710 720 730 740 750
KGNSSAVSKP DAGAGTMGSA HAKTAANSQG ETLPGSKNKV KGNSNAVPKA
760 770 780 790 800
EAGAGTTEPN QPQAEALLGA RNKVKGNSNS VPKAESGAST ILALASSQAE
810 820 830 840 850
ALLGARNKVR GSSNAAPKAE AGVGARGSAQ SQAVVSSQNE ALLGARNKIR
860 870 880 890 900
SNAGTKSGAR TGTRGSAQPQ AVVSSQNEAL LGARDKGLSS SQVEATGDNR
910 920 930 940 950
VYAKPMVGAV PASEMVTVAG AQPNVHDYYW NGIGVEDWIA AERWIKFRFQ
960 970 980 990 1000
TIDGDWENSV SWTEDESGAT IGPWTGAAND KAGLVSSWAV ACDESSIKSW
1010 1020 1030 1040 1050
TGARPENEVA LGSWVSAGDQ ATGAIWAGAQ TTDGTWVADK ASAGSWTGAE
1060 1070 1080 1090 1100
NQISAGSWVV SGNQAIAGPW AVSQVTDGSW PAVQASGVSW VVDQATGTWT
1110 1120 1130 1140 1150
VAENQTGAVS WAGAGNIVSI GYWTGAVDQT NAVSWTGTTD QVGVEVKPRF
1160 1170 1180 1190 1200
EDQASEKGSW VVAGVQTSGE TRLGSEDQSS GRSWTETVDQ ANAASRLGTV
1210 1220 1230 1240 1250
DQAGGTSWAG TGDQVGGVST SGSADQSSSG SWAGTRNLAG ERSWTGTGDQ
1260 1270 1280 1290 1300
SDGAAKPGFE NQTSDEGSWA GTIGQPSGGS KSVSEAQSAG RSWADSADQL
1310 1320 1330 1340 1350
SGGFLVGPLD QANGESQPVS GELAASGVDQ TSGGGCWTGS GDQSGGESRL
1360 1370 1380 1390 1400
GPRDQSNGES WPGTGDQTGG WYCTYTGTQT IGGGPWVGVS GQDVGGPKPV
1410 1420 1430 1440 1450
HMNQATGGAW LGTGTQVSAV SWTGDQVGGC SKPGFEDQAI GGGFWAGAGD
1460 1470 1480 1490 1500
QTTGGSRPAV SEDQSSGGVS WGGAGGHVIG GSRTDQSSGT SWPGMGSQVS
1510 1520 1530 1540 1550
GGSWIGSVDQ TSGCTKSGFE DQTCAGGSWV GTGEQTSGDS WPGSRASNEA
1560 1570 1580 1590 1600
SGGSRLDPQD QASGGSWIRS EDQASGRFLV SAEVEANEGF WFGPGSEAFI
1610 1620 1630 1640 1650
GSWCWTEEAT ILPVAGMKDE ASTESTSGTR EETSISSGLG DEKKTSPESW
1660 1670 1680 1690 1700
TRSEEAALTG TCDGGEAKTV AGAEAEVDPE SKTRAEAKAE AEAETKVEAE
1710 1720 1730 1740 1750
VRVETRAEAG AAATTASEAG AEAGARVEAG AGAEAGMGFW PWNGDDTTKG
1760 1770 1780 1790 1800
SRLGAEAEAG AGGGAEAGAE TENSMGFWFW NGDAATKGSK LGTEAEAETG
1810 1820 1830 1840 1850
IGTGTGAGTG TGTGTGTGVG AGVEVQAVAD TSMGFWFWDG AGATKGSRLG
1860 1870 1880 1890 1900
TEAEAGVGAG AQAGAEAVGG TSMEFWSWDG DEATKGSRLG AEAEPGTGVV
1910 1920 1930 1940 1950
AEPGAETSMG FWFWNEDSTT KGSGLGTEVG AGLGSWTFST NVNDGEEEEE
1960 1970 1980 1990 2000
EDELSRESSP GIEEISLRTL FGAESEDSND LRSTNEKDVS SEPGTGDKAD
2010 2020 2030 2040 2050
DTKDQFDAAN GVDIRSWFYT GNENKCEDES SSQVKVKKST ESRGIYPSMV
2060 2070 2080 2090 2100
PGAGMGVWDG TIVCSESKLL HKTSFPGEDG FRRQVSTGVK VHSCNCRCKR
2110 2120 2130 2140 2150
TVNLDPHDLE KLICMIEMTE DPSVHEIATN ALYNSADYPY PQEIDRNIGG
2160 2170 2180 2190 2200
ISVIQSLLSN PYPNVRQKAL NALNNISVAA ENHRTVKTYL SQVCEDTVTY
2210 2220 2230 2240 2250
PLNSNVQVAG LRLIKHLTIT SEYQHMVTNY ISEFLRLLAL GSGETKDHVL
2260 2270 2280 2290 2300
GMLVNFSKNP SMTRDLLIAN APTALINIFS KKETKENILN ALLLFENINR
2310 2320 2330 2340 2350
HFKKRGKTYP QDRFSKTSLY FLFQRPKACA KKLRALAADC SDPEVKERVE

VLINKL
Length:2,356
Mass (Da):242,954
Last modified:April 5, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE23BAB38913D3828
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BX004852 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
NP_001189429.2, NM_001202500.3
XP_006528531.1, XM_006528468.3
XP_006528532.1, XM_006528469.3
XP_006528533.1, XM_006528470.3
XP_006528535.1, XM_006528472.3

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Mm.31961

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000124226; ENSMUSP00000132914; ENSMUSG00000049804

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
100503043

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:100503043

UCSC genome browser

More...
UCSCi
uc029xmw.1 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX004852 Genomic DNA No translation available.
RefSeqiNP_001189429.2, NM_001202500.3
XP_006528531.1, XM_006528468.3
XP_006528532.1, XM_006528469.3
XP_006528533.1, XM_006528470.3
XP_006528535.1, XM_006528472.3
UniGeneiMm.31961

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Protein-protein interaction databases

IntActiE9PWM3, 1 interactor
STRINGi10090.ENSMUSP00000132914

PTM databases

iPTMnetiE9PWM3
PhosphoSitePlusiE9PWM3

Proteomic databases

MaxQBiE9PWM3
PaxDbiE9PWM3
PeptideAtlasiE9PWM3
PRIDEiE9PWM3

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000124226; ENSMUSP00000132914; ENSMUSG00000049804
GeneIDi100503043
KEGGimmu:100503043
UCSCiuc029xmw.1 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
100131755
MGIiMGI:2147887 Armcx4

Phylogenomic databases

eggNOGiENOG410JB0F Eukaryota
ENOG4111A6X LUCA
GeneTreeiENSGT00940000162587
InParanoidiE9PWM3
OMAiVSIGYWT
OrthoDBiEOG091G0PCU
TreeFamiTF335652

Miscellaneous databases

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000049804 Expressed in 241 organ(s), highest expression level in humerus cartilage element
GenevisibleiE9PWM3 MM

Family and domain databases

InterProiView protein in InterPro
IPR006911 ARM-rpt_dom
IPR016024 ARM-type_fold
IPR000225 Armadillo
PfamiView protein in Pfam
PF04826 Arm_2, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit
PROSITEiView protein in PROSITE
PS50176 ARM_REPEAT, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiE9PWM3_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E9PWM3
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: December 5, 2018
This is version 57 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
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