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Protein
Submitted name:

Trafficking protein particle complex 8

Gene

Trappc8

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-MMU-8876198 RAB GEFs exchange GTP for GDP on RABs

Names & Taxonomyi

Protein namesi
Submitted name:
Trafficking protein particle complex 8Imported
Gene namesi
Name:Trappc8Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 18

Organism-specific databases

MGIiMGI:2443008 Trappc8

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

MaxQBiE9PWG2
PaxDbiE9PWG2
PeptideAtlasiE9PWG2
PRIDEiE9PWG2

PTM databases

iPTMnetiE9PWG2
PhosphoSitePlusiE9PWG2

Expressioni

Gene expression databases

BgeeiENSMUSG00000033382 Expressed in 240 organ(s), highest expression level in blastocyst
ExpressionAtlasiE9PWG2 baseline and differential
GenevisibleiE9PWG2 MM

Interactioni

Protein-protein interaction databases

IntActiE9PWG2, 20 interactors
STRINGi10090.ENSMUSP00000025177

Family & Domainsi

Phylogenomic databases

eggNOGiKOG1938 Eukaryota
ENOG410XPCJ LUCA
GeneTreeiENSGT00390000000568
InParanoidiE9PWG2
OMAiCHRNNLS
OrthoDBiEOG091G062Q
TreeFamiTF106128

Family and domain databases

InterProiView protein in InterPro
IPR011990 TPR-like_helical_dom_sf
IPR024420 TRAPP_III_complex_Trs85
PANTHERiPTHR12975 PTHR12975, 1 hit
PfamiView protein in Pfam
PF12739 TRAPPC-Trs85, 1 hit
SUPFAMiSSF48452 SSF48452, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

E9PWG2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAQCVQSVQE LIPDSFVPCV AALCSDEAER LTRLNHLSFS ELLKPFSRLT
60 70 80 90 100
SEVHMRDPNN QLHIIKNLKI AVSNIVTQPP QPGAIGKLLN DVVSGSQPAE
110 120 130 140 150
GLVANVITAG DYDLNISATT PWFESYRETF LQSMPASDHE FLNHYLACML
160 170 180 190 200
VASSGEAEPM EQFSKLSQEQ HRIQHNNDYS YPKWFIPNTL KYYVLLHDVT
210 220 230 240 250
SGDEQRAESI YEEMKQKYGT QGCYLLKINS RAPNRASDEQ IPDPWSQYLQ
260 270 280 290 300
KNSIQNQESY EDGPCTMTSS KNSDSNLLSL DGLDNEVKVD GLPNNFRIHP
310 320 330 340 350
LQIDQCGDPP NNTDGSESKS ASSVHETKKA STAVIRGACL TLTDHDRIRQ
360 370 380 390 400
FIQEFTFRGL LPHIEKTIRQ LNDQLISRKG LSRSLFSATK KWFSGSKVPE
410 420 430 440 450
KSINELKNTS GLLYPPEAPE LQIRKMADLC FLVQHYDLAY SCYHTAKKDF
460 470 480 490 500
LNDQAMLYAA GALEMAAVSA FLQPGAPRPY PAHYMDTAIQ TYRDICKNMV
510 520 530 540 550
LAERCVLLSA EILKSQSKYS EAAALLIRLT SEDSDLRSAL LLEQAAHCFI
560 570 580 590 600
NMKSPMVRKY AFHMILAGHR FSKAGQKKHA LRCYCQAMQV YKGKGWSLAE
610 620 630 640 650
DHINFTIGRQ SYTLRQLDNA VSAFRHILIN ESKQSAAQQG AFLREYLYVY
660 670 680 690 700
KNVNQLSPDG PLPQLPLPYI NSSATRVFFG HDRRPADGEK QAATHISLDQ
710 720 730 740 750
EYDSESSQQW RELEEHVVAV ANKGVIPSSF YPTQYCLNSY SDNSRFPLAV
760 770 780 790 800
VEEPITVEVA FRNPLKVPLL LSDLSLLWKF QPKDASGKDI EKVKERVTGE
810 820 830 840 850
PEMIGTEVIS EFLINSEESK VARLKLFPHH IGELHILGVV YNLGTIQGSG
860 870 880 890 900
TVDGIGALPG CHTGKHSLSM SVRGRQDLEI QGPRLNNTKE EKTSVKYGPD
910 920 930 940 950
RRLDPIVTEE MPLLEVFFIH FPTGLLCGEI RKAYVEFVNV SKCPLTGLKV
960 970 980 990 1000
VSKRPEFFTF GGNTAALTPL SPSTSENCSA YKTVVTASPS LGTALVSTAS
1010 1020 1030 1040 1050
SMDFGTGTGQ QLEAIPVPLP DSVLLPGASI QLPMWLRGPD EEGVHEINFL
1060 1070 1080 1090 1100
FYYESVKKQP KKRHRILRHT AVICTSRSLN VRATVCRSNS LEDEEGRGGN
1110 1120 1130 1140 1150
MLVFVDVENT NTSEAGVKEF HMVQVSSSSK HWQLHKSVNI SENKDAKLAS
1160 1170 1180 1190 1200
REKGKFCFKA VRCKQKEGGI QSSEKYTFAD IIFGNEQIIS SASPCADFFY
1210 1220 1230 1240 1250
RSLSSELKKT QDQLSAYPEK HREATEGAVR LVEKCSEVDL SIVILWKAYV
1260 1270 1280 1290 1300
VEDNKQLILE GQHHVVVRTV GKEAFSHSQK EEPPEMELLK FFRPENTTVS
1310 1320 1330 1340 1350
TRPSVEQLSN LIKTSLHYPE SFHHPFHQKS LCLVPVTLLL SNCSKADVDV
1360 1370 1380 1390 1400
IVDLRHKTTS PEALETHGSF TWLGQTQYKL QLKSQEMHSL QLKACFVHTG
1410 1420 1430
VYNLGTPRVF AKLSDHVTVF ETSQQNSMPA LIIINNA
Length:1,437
Mass (Da):160,911
Last modified:April 5, 2011 - v1
Checksum:iB9356E5AB047453E
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9PY51E9PY51_MOUSE
Trafficking protein particle comple...
Trappc8
822Annotation score:
A0A286YCX6A0A286YCX6_MOUSE
Trafficking protein particle comple...
Trappc8
1,436Annotation score:
A0A286YCE0A0A286YCE0_MOUSE
Trafficking protein particle comple...
Trappc8
112Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC122118 Genomic DNA No translation available.
AC129078 Genomic DNA No translation available.
RefSeqiNP_796012.2, NM_177038.3
UniGeneiMm.273769

Genome annotation databases

EnsembliENSMUST00000025177; ENSMUSP00000025177; ENSMUSG00000033382
GeneIDi75964
UCSCiuc012bad.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC122118 Genomic DNA No translation available.
AC129078 Genomic DNA No translation available.
RefSeqiNP_796012.2, NM_177038.3
UniGeneiMm.273769

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiE9PWG2, 20 interactors
STRINGi10090.ENSMUSP00000025177

PTM databases

iPTMnetiE9PWG2
PhosphoSitePlusiE9PWG2

Proteomic databases

MaxQBiE9PWG2
PaxDbiE9PWG2
PeptideAtlasiE9PWG2
PRIDEiE9PWG2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000025177; ENSMUSP00000025177; ENSMUSG00000033382
GeneIDi75964
UCSCiuc012bad.1 mouse

Organism-specific databases

CTDi22878
MGIiMGI:2443008 Trappc8

Phylogenomic databases

eggNOGiKOG1938 Eukaryota
ENOG410XPCJ LUCA
GeneTreeiENSGT00390000000568
InParanoidiE9PWG2
OMAiCHRNNLS
OrthoDBiEOG091G062Q
TreeFamiTF106128

Enzyme and pathway databases

ReactomeiR-MMU-8876198 RAB GEFs exchange GTP for GDP on RABs

Miscellaneous databases

ChiTaRSiTrappc8 mouse
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000033382 Expressed in 240 organ(s), highest expression level in blastocyst
ExpressionAtlasiE9PWG2 baseline and differential
GenevisibleiE9PWG2 MM

Family and domain databases

InterProiView protein in InterPro
IPR011990 TPR-like_helical_dom_sf
IPR024420 TRAPP_III_complex_Trs85
PANTHERiPTHR12975 PTHR12975, 1 hit
PfamiView protein in Pfam
PF12739 TRAPPC-Trs85, 1 hit
SUPFAMiSSF48452 SSF48452, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE9PWG2_MOUSE
AccessioniPrimary (citable) accession number: E9PWG2
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: October 10, 2018
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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