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Protein
Submitted name:

Nuclear receptor coactivator 4

Gene

Ncoa4

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

  • cellular iron ion homeostasis Source: MGI
  • protein targeting to lysosome Source: MGI

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear receptor coactivator 4Imported
Gene namesi
Name:Ncoa4Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 14

Organism-specific databases

MGIiMGI:1350932 Ncoa4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

MaxQBiE9PVM8
PRIDEiE9PVM8

Expressioni

Gene expression databases

BgeeiENSMUSG00000056234 Expressed in 26 organ(s), highest expression level in colon
ExpressionAtlasiE9PVM8 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini43 – 131ARA70InterPro annotationAdd BLAST89

Phylogenomic databases

eggNOGiENOG410IHT6 Eukaryota
ENOG410YJ5B LUCA
GeneTreeiENSGT00390000008403

Family and domain databases

InterProiView protein in InterPro
IPR022174 ARA70
IPR039947 NCoA-4
PANTHERiPTHR17085 PTHR17085, 1 hit
PfamiView protein in Pfam
PF12489 ARA70, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All

E9PVM8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAQGTVSRMN TSLEQSGCYS NRETLLRCSD ARRELELAIG GVLRAEQQIK
60 70 80 90 100
DNLREVKAQI HSCISRHLEC LRSREVWLNE QVDLIYQLKE ETLQQQAQQL
110 120 130
YWLMGQFNCL IHQLEYTQNK DLANQVSVCL E
Length:131
Mass (Da):15,271
Last modified:April 5, 2011 - v1
Checksum:i481A819329B23B50
GO

Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q5U4H9Q5U4H9_MOUSE
Nuclear receptor coactivator 4
Ncoa4
625Annotation score:
E9Q0D2E9Q0D2_MOUSE
Nuclear receptor coactivator 4
Ncoa4
205Annotation score:
E9PWU9E9PWU9_MOUSE
Nuclear receptor coactivator 4
Ncoa4
99Annotation score:
E9Q2H3E9Q2H3_MOUSE
Nuclear receptor coactivator 4
Ncoa4
338Annotation score:
E9Q8Q4E9Q8Q4_MOUSE
Nuclear receptor coactivator 4
Ncoa4
96Annotation score:
E9PZ59E9PZ59_MOUSE
Nuclear receptor coactivator 4
Ncoa4
106Annotation score:
A0A2I3BRC7A0A2I3BRC7_MOUSE
Nuclear receptor coactivator 4
Ncoa4
102Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei131Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC154532 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSMUST00000168034; ENSMUSP00000129422; ENSMUSG00000056234

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC154532 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiE9PVM8
PRIDEiE9PVM8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000168034; ENSMUSP00000129422; ENSMUSG00000056234

Organism-specific databases

MGIiMGI:1350932 Ncoa4

Phylogenomic databases

eggNOGiENOG410IHT6 Eukaryota
ENOG410YJ5B LUCA
GeneTreeiENSGT00390000008403

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000056234 Expressed in 26 organ(s), highest expression level in colon
ExpressionAtlasiE9PVM8 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR022174 ARA70
IPR039947 NCoA-4
PANTHERiPTHR17085 PTHR17085, 1 hit
PfamiView protein in Pfam
PF12489 ARA70, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE9PVM8_MOUSE
AccessioniPrimary (citable) accession number: E9PVM8
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: November 7, 2018
This is version 33 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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