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Entry version 87 (29 Sep 2021)
Sequence version 1 (05 Apr 2011)
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Protein
Submitted name:

Talin-2

Gene

Tln2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Talin-2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Tln2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 9

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1917799, Tln2

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSMUSG00000052698

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

CytoplasmARBA annotation

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PeptideAtlas

More...
PeptideAtlasi
E9PUM4

PRoteomics IDEntifications database

More...
PRIDEi
E9PUM4

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
334481

PTM databases

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
E9PUM4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000052698, Expressed in adult mammalian kidney and 265 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
E9PUM4, baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
E9PUM4

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini88 – 406FERMInterPro annotationAdd BLAST319
Domaini2294 – 2533I/LWEQInterPro annotationAdd BLAST240

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1052 – 1079Sequence analysisAdd BLAST28
Coiled coili1237 – 1257Sequence analysisAdd BLAST21
Coiled coili2501 – 2528Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154699

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000364_1_1_1

Identification of Orthologs from Complete Genome Data

More...
OMAi
NMVKHSK

Database of Orthologous Groups

More...
OrthoDBi
9839at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
E9PUM4

TreeFam database of animal gene trees

More...
TreeFami
TF314677

Family and domain databases

Conserved Domains Database

More...
CDDi
cd14473, FERM_B-lobe, 1 hit
cd12150, talin-RS, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.80.10, 1 hit
2.30.29.30, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036723, Alpha-catenin/vinculin-like_sf
IPR019749, Band_41_domain
IPR014352, FERM/acyl-CoA-bd_prot_sf
IPR035963, FERM_2
IPR019748, FERM_central
IPR019747, FERM_CS
IPR000299, FERM_domain
IPR032425, FERM_f0
IPR035964, I/LWEQ_dom_sf
IPR002558, ILWEQ_dom
IPR011993, PH-like_dom_sf
IPR037438, Talin1/2-RS
IPR015224, Talin_cent
IPR036476, Talin_cent_sf
IPR029071, Ubiquitin-like_domsf
IPR015009, Vinculin-bd_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF16511, FERM_f0, 1 hit
PF00373, FERM_M, 1 hit
PF01608, I_LWEQ, 3 hits
PF09141, Talin_middle, 1 hit
PF08913, VBS, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00295, B41, 1 hit
SM00307, ILWEQ, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF109880, SSF109880, 1 hit
SSF109885, SSF109885, 5 hits
SSF47031, SSF47031, 1 hit
SSF47220, SSF47220, 5 hits
SSF54236, SSF54236, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00661, FERM_2, 1 hit
PS50057, FERM_3, 1 hit
PS50945, I_LWEQ, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

E9PUM4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVALSLKICV RHCNVVKTMQ FEPSTAVYDA CRVIRERVPE AQTGQASDYG
60 70 80 90 100
LFLSDEDPRK GIWLEAGRTL DYYMLRNGDI LEYKKKQRPQ KIRMLDGSVK
110 120 130 140 150
TVMVDDSKTV GELLVTICSR IGITNYEEYS LIQETIEEKK EEGTGTLKKD
160 170 180 190 200
RTLLRDERKM EKLKAKLHTD DDLNWLDHSR TFREQGVDEN ETLLLRRKFF
210 220 230 240 250
YSDQNVDSRD PVQLNLLYVQ ARDDILNGSH PVSFEKACEF GGFQAQIQFG
260 270 280 290 300
PHVEHKHKPG FLDLKEFLPK EYIKQRGAEK RIFQEHKNCG EMSEIEAKVK
310 320 330 340 350
YVKLARSLRT YGVSFFLVKE KMKGKNKLVP RLLGITKDSV MRVDEKTKEV
360 370 380 390 400
LQEWPLTTVK RWAASPKSFT LDFGEYQESY YSVQTTEGEQ ISQLIAGYID
410 420 430 440 450
IILKKKQSKD RFGLEGDEES TMLEESVSPK KSTILQQQFN RTGKAEHGSV
460 470 480 490 500
ALPAVMRSGS SGPETFNVGS MPSPQQQVMV GQMHRGHMPP LTSAQQALMG
510 520 530 540 550
TINTSMHAVQ QAQDDLSELD SLPPLGQDMA SRVWVQNKVD ESKHEIHSQV
560 570 580 590 600
DAITAGTASV VNLTAGDPAD TDYTAVGCAI TTISSNLTEM SKGVKLLAAL
610 620 630 640 650
MDDDVGSGED LLRAARTLAG AVSDLLKAVQ PTSGEPRQTV LTAAGSIGQA
660 670 680 690 700
SGDLLRQIGE NETDERFQDV LMSLAKAVAN AAAMLVLKAK NVAQVAEDTV
710 720 730 740 750
LQNRVIAAAT QCALSTSQLV ACAKVVSPTI SSPVCQEQLI EAGKLVDRSV
760 770 780 790 800
ENCVRACQAA TSDSELLKQV SAAASVVSQA LHDLLQHVRQ FASRGEPIGR
810 820 830 840 850
YDQATDTIMC VTESIFSSMG DAGEMVRQAR VLAQATSDLV NAMRSDAEAE
860 870 880 890 900
IDMENSKKLL AAAKLLADST ARMVEAAKGA AANPENEDQQ QRLREAAEGL
910 920 930 940 950
RVATNAAAQN AIKKKIVNRL EVAAKQAAAA ATQTIAASQN AAISNKNPSA
960 970 980 990 1000
QQQLVQSCKA VADHIPQLVQ GVRGSQAQAE DLSAQLALII SSQNFLQPGS
1010 1020 1030 1040 1050
KMVSSAKAAV PTVSDQAAAM QLSQCAKNLA TSLAELRTAS QKAHEACGPM
1060 1070 1080 1090 1100
EIDSALNTVQ TLKNELQDAK MAAAESQLKP LPGETLEKCA QDLGSTSKGV
1110 1120 1130 1140 1150
GSSMAQLLTC AAQGNEHYTG VAARETAQAL KTLAQAARGV AASTNDPEAA
1160 1170 1180 1190 1200
HAMLDSARDV MEGSAMLIQE AKQALIAPGD TESQQRLAQV AKAVSHSLNN
1210 1220 1230 1240 1250
CVNCLPGQKD VDVALKSIGE ASKKLLVDSL PPSTKPFQEA QSELNQAAAD
1260 1270 1280 1290 1300
LNQSAGEVVH ATRGQSGELA AASGKFSDDF DEFLDAGIEM AGQAQTKEDQ
1310 1320 1330 1340 1350
MQVIGNLKNI SMASSKLLLA AKSLSVDPGA PNAKNLLAAA ARAVTESINQ
1360 1370 1380 1390 1400
LIMLCTQQAP GQKECDNALR ELETVKGMLE NPNEPVSDLS YFDCIESVME
1410 1420 1430 1440 1450
NSKVLGESMA GISQNAKTGD LPAFGECVGI ASKALCGLTE AAAQAAYLVG
1460 1470 1480 1490 1500
ISDPNSQAGH QGLVDPIQFA RANQAIQMAC QNLVDPGSSP SQVLSAATIV
1510 1520 1530 1540 1550
AKHTSALCNA CRIASSKTAN PVAKRHFVQS AKEVANSTAN LVKTIKALDG
1560 1570 1580 1590 1600
DFSEDNRNKC RIATTPLIEA VENLTAFASN PEFASIPAQI SSEGSQAQEP
1610 1620 1630 1640 1650
ILVSAKTMLE SSSYLIRTAR SLAINPKDPP TWSVLAGHSH TVSDSIKSLI
1660 1670 1680 1690 1700
TSIRDKAPGQ RECDYSIDGI NRCIRDIEQA SLAAVSQSLA TRDDISVEAL
1710 1720 1730 1740 1750
QEQLTSVVQE IGHLIDPIAT AARGEAAQLG HKVTQLASYF EPLILAAVGV
1760 1770 1780 1790 1800
ASKMLDHQQQ MTVLDQTKTL AESALQMLYA AKEGGGNPKA QHTHDAITEA
1810 1820 1830 1840 1850
AQLMKEAVDD IMVTLNEAAS EVGLVGGMVD AIAEAMSKLD EGTPPEPKGT
1860 1870 1880 1890 1900
FVDYQTTVVK YSKAIAVTAQ EMMTKSVTNP EELGGLASQM TTDYGHLALQ
1910 1920 1930 1940 1950
GQMAAATAEP EEIGFQIRTR VQDLGHGCIF LVQKAGALQV CPTDSYTKRE
1960 1970 1980 1990 2000
LIECARSVTE KVSLVLSALQ AGNKGTQACI TAATAVSGII ADLDTTIMFA
2010 2020 2030 2040 2050
TAGTLNAENG ETFADHRENI LKTAKALVED TKLLVSGAAS TPDKLAQAAQ
2060 2070 2080 2090 2100
SSAATITQLA EVVKLGAASL GSNDPETQVV LINAIKDVAK ALSDLIGATK
2110 2120 2130 2140 2150
GAASKPADDP SMYQLKGAAK VMVTNVTSLL KTVKAVEDEA TRGTRALEAT
2160 2170 2180 2190 2200
IEYIKQELTV FQSKDIPEKT SSPEESIRMT KGITMATAKA VAAGNSCRQE
2210 2220 2230 2240 2250
DVIATANLSR KAVSDMLIAC KQASFYPDVS EEVRTRALRY GTECTLGYLD
2260 2270 2280 2290 2300
LLEHVLVILQ KPTPELKHQL AAFSKRVAGA VTELIQAAEA MKGTEWVDPE
2310 2320 2330 2340 2350
DPTVIAETEL LGAAASIEAA AKKLEQLKPR AKPKQADETL DFEEQILEAA
2360 2370 2380 2390 2400
KSIAAATSAL VKSASAAQRE LVAQGKVGSI PANAADDGQW SQGLISAARM
2410 2420 2430 2440 2450
VAAATSSLCE AANASVQGHA SEEKLISSAK QVAASTAQLL VACKVKADQD
2460 2470 2480 2490 2500
SEAMKRLQAA GNAVKRASDN LVRAAQKAAF GKADDDDVVV KTKFVGGIAQ
2510 2520 2530 2540
IIAAQEEMLK KERELEEARK KLAQIRQQQY KFLPTELRED EG
Length:2,542
Mass (Da):271,667
Last modified:April 5, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDF5FCF24035E5011
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q71LX4TLN2_MOUSE
Talin-2
Tln2
2,375Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1L1SQ51A0A1L1SQ51_MOUSE
Talin-2
Tln2
2,544Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q8CDM9Q8CDM9_MOUSE
Talin-2
Tln2
1,452Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1L1SRI1A0A1L1SRI1_MOUSE
Talin-2
Tln2
1,471Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1L1SQP9A0A1L1SQP9_MOUSE
Talin-2
Tln2
923Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1L1SVA8A0A1L1SVA8_MOUSE
Talin-2
Tln2
137Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

NCBI Reference Sequences

More...
RefSeqi
NP_001074711.2, NM_001081242.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000039662; ENSMUSP00000035272; ENSMUSG00000052698
ENSMUST00000040025; ENSMUSP00000039633; ENSMUSG00000052698

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
70549

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:70549

UCSC genome browser

More...
UCSCi
uc012gvz.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiNP_001074711.2, NM_001081242.2

3D structure databases

SMRiE9PUM4
ModBaseiSearch...

PTM databases

SwissPalmiE9PUM4

Proteomic databases

PeptideAtlasiE9PUM4
PRIDEiE9PUM4
ProteomicsDBi334481

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
25560, 197 antibodies

Genome annotation databases

EnsembliENSMUST00000039662; ENSMUSP00000035272; ENSMUSG00000052698
ENSMUST00000040025; ENSMUSP00000039633; ENSMUSG00000052698
GeneIDi70549
KEGGimmu:70549
UCSCiuc012gvz.1, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
83660
MGIiMGI:1917799, Tln2
VEuPathDBiHostDB:ENSMUSG00000052698

Phylogenomic databases

GeneTreeiENSGT00940000154699
HOGENOMiCLU_000364_1_1_1
OMAiNMVKHSK
OrthoDBi9839at2759
PhylomeDBiE9PUM4
TreeFamiTF314677

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
70549, 2 hits in 65 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Tln2, mouse

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000052698, Expressed in adult mammalian kidney and 265 other tissues
ExpressionAtlasiE9PUM4, baseline and differential

Family and domain databases

CDDicd14473, FERM_B-lobe, 1 hit
cd12150, talin-RS, 1 hit
Gene3Di1.20.80.10, 1 hit
2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR036723, Alpha-catenin/vinculin-like_sf
IPR019749, Band_41_domain
IPR014352, FERM/acyl-CoA-bd_prot_sf
IPR035963, FERM_2
IPR019748, FERM_central
IPR019747, FERM_CS
IPR000299, FERM_domain
IPR032425, FERM_f0
IPR035964, I/LWEQ_dom_sf
IPR002558, ILWEQ_dom
IPR011993, PH-like_dom_sf
IPR037438, Talin1/2-RS
IPR015224, Talin_cent
IPR036476, Talin_cent_sf
IPR029071, Ubiquitin-like_domsf
IPR015009, Vinculin-bd_dom
PfamiView protein in Pfam
PF16511, FERM_f0, 1 hit
PF00373, FERM_M, 1 hit
PF01608, I_LWEQ, 3 hits
PF09141, Talin_middle, 1 hit
PF08913, VBS, 1 hit
SMARTiView protein in SMART
SM00295, B41, 1 hit
SM00307, ILWEQ, 1 hit
SUPFAMiSSF109880, SSF109880, 1 hit
SSF109885, SSF109885, 5 hits
SSF47031, SSF47031, 1 hit
SSF47220, SSF47220, 5 hits
SSF54236, SSF54236, 1 hit
PROSITEiView protein in PROSITE
PS00661, FERM_2, 1 hit
PS50057, FERM_3, 1 hit
PS50945, I_LWEQ, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiE9PUM4_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E9PUM4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: September 29, 2021
This is version 87 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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