Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 76 (11 Dec 2019)
Sequence version 1 (05 Apr 2011)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein
Submitted name:

RNA-binding protein 26

Gene

Rbm26

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri288 – 316C3H1-typePROSITE-ProRule annotationAdd BLAST29

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRNA-bindingPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
RNA-binding protein 26Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Rbm26Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 14

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1921463 Rbm26

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
E9PUF4

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
E9PUF4

MaxQB - The MaxQuant DataBase

More...
MaxQBi
E9PUF4

PeptideAtlas

More...
PeptideAtlasi
E9PUF4

PRoteomics IDEntifications database

More...
PRIDEi
E9PUF4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000022119 Expressed in 274 organ(s), highest expression level in pineal body

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
E9PUF4 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
E9PUF4 MM

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini288 – 316C3H1-typeInterPro annotationAdd BLAST29
Domaini532 – 606RRMInterPro annotationAdd BLAST75
Domaini867 – 936RRMInterPro annotationAdd BLAST70

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni106 – 236DisorderedSequence analysisAdd BLAST131
Regioni334 – 404DisorderedSequence analysisAdd BLAST71
Regioni460 – 519DisorderedSequence analysisAdd BLAST60
Regioni642 – 664DisorderedSequence analysisAdd BLAST23
Regioni829 – 860DisorderedSequence analysisAdd BLAST32
Regioni941 – 983DisorderedSequence analysisAdd BLAST43

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili696 – 719Sequence analysisAdd BLAST24
Coiled coili746 – 766Sequence analysisAdd BLAST21
Coiled coili800 – 820Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi106 – 124PolyampholyteSequence analysisAdd BLAST19
Compositional biasi135 – 170PolyampholyteSequence analysisAdd BLAST36
Compositional biasi183 – 226PolyampholyteSequence analysisAdd BLAST44
Compositional biasi334 – 392Pro-richSequence analysisAdd BLAST59
Compositional biasi648 – 664PolarSequence analysisAdd BLAST17
Compositional biasi837 – 853BasicSequence analysisAdd BLAST17
Compositional biasi945 – 975AcidicSequence analysisAdd BLAST31

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri288 – 316C3H1-typePROSITE-ProRule annotationAdd BLAST29

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2135 Eukaryota
ENOG41119BA LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00510000046929

KEGG Orthology (KO)

More...
KOi
K13192

Database of Orthologous Groups

More...
OrthoDBi
741871at2759

TreeFam database of animal gene trees

More...
TreeFami
TF319253

Family and domain databases

Conserved Domains Database

More...
CDDi
cd12516 RRM1_RBM26, 1 hit
cd12258 RRM2_RBM26_like, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.70.330, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR002483 PWI_dom
IPR035979 RBD_domain_sf
IPR034861 RBM26
IPR039511 RBM26-like_RRM2
IPR034859 RBM26_RRM1
IPR000504 RRM_dom
IPR000571 Znf_CCCH

The PANTHER Classification System

More...
PANTHERi
PTHR14398:SF2 PTHR14398:SF2, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01480 PWI, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00360 RRM, 2 hits
SM00356 ZnF_C3H1, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54928 SSF54928, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50102 RRM, 2 hits
PS50103 ZF_C3H1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

E9PUF4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVSKMIIENF EALKSWLSKT LEPICDADPS ALAKYVLALV KKDKSEKELK
60 70 80 90 100
ALCIDQLDVF LQKETQIFVE KLFDAVNTKS YLPPPEQPSS GSLKVDFLQH
110 120 130 140 150
QEKDIKKEEL TKEEEREKKF SRRLNHSPPQ SSSRYRDNRS RDERKKDDRS
160 170 180 190 200
RKRDYDRNPP RRDSYRDRYN RRRGRSRSYS RSRSRSWSKE RLRDRDRDRS
210 220 230 240 250
RTRSRSRTRS RERDLVKPKY DLDRTDPLEN NYTPVSSVSN ISSGHYPVPT
260 270 280 290 300
LSSTITVIAP THHGNNTTES WSEFHEDQVD HNSYVRPPMP KKRCRDYDEK
310 320 330 340 350
GFCMRGDMCP FDHGSDPVVV EDVNLPGMLP FPAQPPVVEG PPPPGLPPPP
360 370 380 390 400
PILTPPPVNL RPPVPPPGPL PPSLPPVTGP PPPLPPLQPS GMDAPPNSAT
410 420 430 440 450
SSVPTVVTTG IHHQPPPAPP SLFTADTYDT DGYNPEAPSI TNTSRPMYRH
460 470 480 490 500
RVHAQRPNLI GLTSGDMDLP PREKPPNKSS MRIVVDSESR KRTIGSGEPG
510 520 530 540 550
VSTKKTWFDK PNFNRTNSPG FQKKVQFGNE NTKLELRKVP PELNNISKLN
560 570 580 590 600
EHFSRFGTLV NLQVAYNGDP EGALIQFATY EEAKKAISST EAVLNNRFIK
610 620 630 640 650
VYWHREGTTQ QLQTTSPKVI QPLVQQPILP VVKQSVKERL GPVPSATTEP
660 670 680 690 700
AEAQSATSEL PQVLSTSTGL TKTVYNPAAL KAAQKTLSVS TPAVDNNEAQ
710 720 730 740 750
KKKQEALKLQ QDVRKRKQEI LEKHIETQKM LISKLEKNKT MKSEDKAEIM
760 770 780 790 800
KTLEILTKNI TKLKDEVKST SPGRCLPKSI KTKTQMQKEL LDTELDLYKK
810 820 830 840 850
MQAGEEVTEL RRKYTELQLE AAKRGILSSG RGRGIHTRGR GTAHGRGRGR
860 870 880 890 900
GRGRGVPGHA VVDHRPRALE ISAFTESDRE DLLPHFAQYG EIEDCQIDDA
910 920 930 940 950
SLHAIITFKT RAEAEAAAIH GARFKGQDLK LAWNKPIANM SAVDTEEAEP
960 970 980
DEEEFQEESL VDDSLLQDDD EEEEDNESRS WRR
Length:983
Mass (Da):111,014
Last modified:April 5, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC8003F36439F7004
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q6NZN0RBM26_MOUSE
RNA-binding protein 26
Rbm26
1,012Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9Q640E9Q640_MOUSE
RNA-binding protein 26
Rbm26
1,001Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PYZ7E9PYZ7_MOUSE
RNA-binding protein 26
Rbm26
1,009Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0R4J214A0A0R4J214_MOUSE
RNA-binding protein 26
Rbm26
210Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC113125 Genomic DNA No translation available.
AC146601 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
NP_598838.3, NM_134077.4

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000100327; ENSMUSP00000097901; ENSMUSG00000022119

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
74213

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:74213

UCSC genome browser

More...
UCSCi
uc007uxk.1 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC113125 Genomic DNA No translation available.
AC146601 Genomic DNA No translation available.
RefSeqiNP_598838.3, NM_134077.4

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Proteomic databases

EPDiE9PUF4
jPOSTiE9PUF4
MaxQBiE9PUF4
PeptideAtlasiE9PUF4
PRIDEiE9PUF4

Genome annotation databases

EnsembliENSMUST00000100327; ENSMUSP00000097901; ENSMUSG00000022119
GeneIDi74213
KEGGimmu:74213
UCSCiuc007uxk.1 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
64062
MGIiMGI:1921463 Rbm26

Phylogenomic databases

eggNOGiKOG2135 Eukaryota
ENOG41119BA LUCA
GeneTreeiENSGT00510000046929
KOiK13192
OrthoDBi741871at2759
TreeFamiTF319253

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Rbm26 mouse

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000022119 Expressed in 274 organ(s), highest expression level in pineal body
ExpressionAtlasiE9PUF4 baseline and differential
GenevisibleiE9PUF4 MM

Family and domain databases

CDDicd12516 RRM1_RBM26, 1 hit
cd12258 RRM2_RBM26_like, 1 hit
Gene3Di3.30.70.330, 2 hits
InterProiView protein in InterPro
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR002483 PWI_dom
IPR035979 RBD_domain_sf
IPR034861 RBM26
IPR039511 RBM26-like_RRM2
IPR034859 RBM26_RRM1
IPR000504 RRM_dom
IPR000571 Znf_CCCH
PANTHERiPTHR14398:SF2 PTHR14398:SF2, 2 hits
PfamiView protein in Pfam
PF01480 PWI, 1 hit
SMARTiView protein in SMART
SM00360 RRM, 2 hits
SM00356 ZnF_C3H1, 1 hit
SUPFAMiSSF54928 SSF54928, 2 hits
PROSITEiView protein in PROSITE
PS50102 RRM, 2 hits
PS50103 ZF_C3H1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiE9PUF4_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E9PUF4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: December 11, 2019
This is version 76 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again