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Entry version 69 (02 Jun 2021)
Sequence version 2 (03 Apr 2013)
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Protein

C-Jun-amino-terminal kinase-interacting protein 3

Gene

Mapk8ip3

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins (By similarity).

Promotes neuronal axon elongation in a kinesin- and JNK-dependent manner. Activates cofilin at axon tips via local activation of JNK, thereby regulating filopodial dynamics and enhancing axon elongation. Its binding to kinesin heavy chains (KHC), promotes kinesin-1 motility along microtubules and is essential for axon elongation and regeneration. Regulates cortical neuronal migration by mediating NTRK2/TRKB anterograde axonal transport during brain development. Acts as an adapter that bridges the interaction between NTRK2/TRKB and KLC1 and drives NTRK2/TRKB axonal but not dendritic anterograde transport, which is essential for subsequent BDNF-triggered signaling and filopodia formation.

By similarity4 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
C-Jun-amino-terminal kinase-interacting protein 3
Short name:
JIP-3
Short name:
JNK-interacting protein 3
Alternative name(s):
JNK MAP kinase scaffold protein 3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Mapk8ip3
Synonyms:Jip3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002494 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Rat genome database

More...
RGDi
1563691, Mapk8ip3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cell projection, Cytoplasm, Cytoplasmic vesicle, Golgi apparatus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004448931 – 1322C-Jun-amino-terminal kinase-interacting protein 3Add BLAST1322

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei266PhosphothreonineBy similarity1
Modified residuei276PhosphothreonineBy similarity1
Modified residuei287PhosphothreonineBy similarity1
Modified residuei315PhosphoserineBy similarity1
Modified residuei365PhosphoserineBy similarity1
Modified residuei366PhosphoserineBy similarity1
Modified residuei588PhosphoserineBy similarity1
Modified residuei662PhosphoserineBy similarity1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Phosphorylation by ROCK1 is crucial for the recruitment of JNK.By similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
E9PSK7

PeptideAtlas

More...
PeptideAtlasi
E9PSK7

PRoteomics IDEntifications database

More...
PRIDEi
E9PSK7

PTM databases

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
E9PSK7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSRNOG00000033568, Expressed in frontal cortex and 21 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Forms homo- or heterooligomeric complexes. The central region of MAPK8IP3 interacts with the C-terminal of MAPK8IP2 but not MAPK8IP1. Binds specific components of the JNK signaling pathway namely MAPK8/JNK1, MAPK9/JNK2 and MAPK10/JNK3 to the N-terminal region, MAP2K4/MKK4 and MAP2K7/MKK7 to the central region and MAP3K11 to the C-terminal region. Binds the TPR motif-containing C-terminal of kinesin light chain, KLC1. Pre-assembled MAPK8IP1 scaffolding complexes are then transported as a cargo of kinesin, to the required subcellular location.

Interacts with ROCK1 and this interaction is enhanced by ultraviolet-B (UVB) radiation (By similarity).

Interacts with SH3RF2 (PubMed:22128169).

Interacts with NTRK3/TRKC (By similarity).

Interacts with NTRK2/TRKB (PubMed:21775604).

By similarity3 Publications

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10116.ENSRNOP00000039682

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini12 – 100RH1PROSITE-ProRule annotationAdd BLAST89
Domaini506 – 580RH2PROSITE-ProRule annotationAdd BLAST75

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni50 – 80Kinesin-binding domain (KBD); essential for its function in axon elongationBy similarityAdd BLAST31
Regioni183 – 211DisorderedSequence analysisAdd BLAST29
Regioni210 – 226JNK-binding domain (JBD); essential for its function in axon elongationBy similarityAdd BLAST17
Regioni245 – 317DisorderedSequence analysisAdd BLAST73
Regioni424 – 459Leucine zipper-like domain (LZ); essential for its function in axon elongation1 PublicationAdd BLAST36
Regioni459 – 515Interaction with NTRK21 PublicationAdd BLAST57
Regioni704 – 754DisorderedSequence analysisAdd BLAST51
Regioni844 – 952DisorderedSequence analysisAdd BLAST109
Regioni1281 – 1307DisorderedSequence analysisAdd BLAST27

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili66 – 167Sequence analysisAdd BLAST102
Coiled coili443 – 534Sequence analysisAdd BLAST92

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi245 – 301Polar residuesSequence analysisAdd BLAST57
Compositional biasi722 – 752Basic and acidic residuesSequence analysisAdd BLAST31
Compositional biasi868 – 883Polar residuesSequence analysisAdd BLAST16
Compositional biasi911 – 952Polar residuesSequence analysisAdd BLAST42

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the JIP scaffold family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2077, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153496

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_003841_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
E9PSK7

Identification of Orthologs from Complete Genome Data

More...
OMAi
CLRRIKM

Database of Orthologous Groups

More...
OrthoDBi
324912at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.130.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR039911, JIP3/JIP4
IPR032486, JIP_LZII
IPR019143, JNK/Rab-associated_protein-1_N
IPR034743, RH1
IPR034744, RH2
IPR015943, WD40/YVTN_repeat-like_dom_sf
IPR036322, WD40_repeat_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR13886, PTHR13886, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF16471, JIP_LZII, 1 hit
PF09744, Jnk-SapK_ap_N, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50978, SSF50978, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51776, RH1, 1 hit
PS51777, RH2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

E9PSK7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMEIQMDEGG GVVVYQDDYC SGSVMSERVS GLAGSIYREF ERLIHCYDEE
60 70 80 90 100
VVKELMPLVV NVLENLDSVL SENQEHEVEL ELLREDNEQL LTQYEREKAL
110 120 130 140 150
RKQAEEKFIE FEDALEQEKK ELQIQVEHYE FQTRQLELKA KNYADQISRL
160 170 180 190 200
EERESEMKKE YNALHQRHTE MIQTYVEHIE RSKMQQVGGG GQTESSLPGR
210 220 230 240 250
SRKERPTSLN VFPLADGMVR AQMGGKLVPA GDHWHLSDLG QLQSSSSYQC
260 270 280 290 300
PNDEMSESGQ SSAAATPSTT GTKSNTPTSS VPSAAVTPLN ESLQPLGDYG
310 320 330 340 350
SVTKNNKRAR EKRNSRNMEV QVTQEMRNVS IGMGSSDEWS DVQDIIDSTP
360 370 380 390 400
ELDVCPETRL DRTGSSPTQG IVNKAFGINT DSLYHELSTA GSEVIGDVDE
410 420 430 440 450
GADLLGEFSG MGKEVGNLLL ENSQLLETKN ALNVVKNDLI AKVDQLSGEQ
460 470 480 490 500
EVLKGELEAA KQAKVKLENR IKELEEELKR VKSEAVTARR EPREEVEDDK
510 520 530 540 550
IPMAQRRRFT RVEMARVLME RNQYKERLME LQEAVRWTEM IRASREHPSV
560 570 580 590 600
QEKKKSTIWQ FFSRLFSSSS SPPPAKRSYP SVNIHYKSPT TAGFSQRRNH
610 620 630 640 650
ALCQISAGSR PLEFFPDDDC TSSARREQKR EQYRQVREHV RNDDGRLQAC
660 670 680 690 700
GWSLPAKYKQ LSPNGGQEDT RMKNVPVPVY CRPLVEKDPS TKLWCAAGVN
710 720 730 740 750
LSGWKPNEED SSNGPKPAPG RDPLTCDREG EGEPKSTHPS PEKKKAKEVP
760 770 780 790 800
EADATSSRVW ILTSTLTTSK VVIIDANQPG TVVDQFTVCN AHVLCISSIP
810 820 830 840 850
AASDSDYPPG DMFLDSDVNP EDSGADGVLA GITLVGCATR CNVPRSNCSS
860 870 880 890 900
RGDTPVLDKG QGDVAATANG KVNPSQSTEE ATEATEVPDP GPSESEATTV
910 920 930 940 950
RPGPLTEHVF TDPAPTQSSS TQPASENGSE SDGSIVQPQV EPSGESSATT
960 970 980 990 1000
SSAAPTMWLG AQNGWLYVHS AVANWKKCLH SIKLKDSVLS LVHVKGRVLV
1010 1020 1030 1040 1050
ALADGTLAIF HRGEDGQWDL SNYHLMDLGH PHHSIRCMAV VDDRVWCGYK
1060 1070 1080 1090 1100
NKVHVIQPKT MQIEKSFDAH PRRESQVRQL AWIGDGVWVS IRLDSTLRLY
1110 1120 1130 1140 1150
HAHTHQHLQD VDIEPYVSKM LGTGKLGFSF VRITALLIAG NRLWVGTGNG
1160 1170 1180 1190 1200
VVISIPLTET VVLHRGQLLG LRANKTSPTS GEGTRPGGII HVYGDDSSDK
1210 1220 1230 1240 1250
TASSFIPYCS MAQAQLCFHG HRDAVKFFVS VPGNVLATLN GSVLDSPSEG
1260 1270 1280 1290 1300
PGPAAPAADA EGQKLKNALV LSGGEGYIDF RIGDGEDDET EEGTGDVNQT
1310 1320
KPSLSKAERS HIIVWQVSYT PE
Length:1,322
Mass (Da):145,650
Last modified:April 3, 2013 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i01C4DAF1DFEDAA35
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti440I → V in ABD24061 (PubMed:21076496).Curated1
Sequence conflicti940V → M in ABD24061 (PubMed:21076496).Curated1
Sequence conflicti1208Y → N in ABD24061 (PubMed:21076496).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
DQ377222 mRNA Translation: ABD24061.1
AC130925 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
NP_001094143.1, NM_001100673.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSRNOT00000042066; ENSRNOP00000039682; ENSRNOG00000033568

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
302983

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
rno:302983

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ377222 mRNA Translation: ABD24061.1
AC130925 Genomic DNA No translation available.
RefSeqiNP_001094143.1, NM_001100673.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000039682

PTM databases

PhosphoSitePlusiE9PSK7

Proteomic databases

PaxDbiE9PSK7
PeptideAtlasiE9PSK7
PRIDEiE9PSK7

Genome annotation databases

EnsembliENSRNOT00000042066; ENSRNOP00000039682; ENSRNOG00000033568
GeneIDi302983
KEGGirno:302983

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
23162
RGDi1563691, Mapk8ip3

Phylogenomic databases

eggNOGiKOG2077, Eukaryota
GeneTreeiENSGT00940000153496
HOGENOMiCLU_003841_0_0_1
InParanoidiE9PSK7
OMAiCLRRIKM
OrthoDBi324912at2759

Miscellaneous databases

Protein Ontology

More...
PROi
PR:E9PSK7

Gene expression databases

BgeeiENSRNOG00000033568, Expressed in frontal cortex and 21 other tissues

Family and domain databases

Gene3Di2.130.10.10, 1 hit
InterProiView protein in InterPro
IPR039911, JIP3/JIP4
IPR032486, JIP_LZII
IPR019143, JNK/Rab-associated_protein-1_N
IPR034743, RH1
IPR034744, RH2
IPR015943, WD40/YVTN_repeat-like_dom_sf
IPR036322, WD40_repeat_dom_sf
PANTHERiPTHR13886, PTHR13886, 1 hit
PfamiView protein in Pfam
PF16471, JIP_LZII, 1 hit
PF09744, Jnk-SapK_ap_N, 1 hit
SUPFAMiSSF50978, SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS51776, RH1, 1 hit
PS51777, RH2, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiJIP3_RAT
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E9PSK7
Secondary accession number(s): B0VXR4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 18, 2018
Last sequence update: April 3, 2013
Last modified: June 2, 2021
This is version 69 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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