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Protein
Submitted name:

Alpha-parvin

Gene

PARVA

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Alpha-parvinImported
Gene namesi
Name:PARVAImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000197702.11
HGNCiHGNC:14652 PARVA

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000197702

PTM / Processingi

Proteomic databases

MaxQBiE9PS97
PeptideAtlasiE9PS97
PRIDEiE9PS97

Expressioni

Gene expression databases

BgeeiENSG00000197702 Expressed in 225 organ(s), highest expression level in lower esophagus
ExpressionAtlasiE9PS97 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliE9PS97
SMRiE9PS97
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini59 – 166Calponin-homology (CH)InterPro annotationAdd BLAST108

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili93 – 113Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG3631 Eukaryota
ENOG410XQWH LUCA
GeneTreeiENSGT00390000009673

Family and domain databases

Gene3Di1.10.418.10, 1 hit
InterProiView protein in InterPro
IPR001715 CH-domain
IPR036872 CH_dom_sf
IPR028433 Parvin
PANTHERiPTHR12114 PTHR12114, 1 hit
PfamiView protein in Pfam
PF00307 CH, 1 hit
SUPFAMiSSF47576 SSF47576, 1 hit
PROSITEiView protein in PROSITE
PS50021 CH, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

E9PS97-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGCGALCPQV SELQEEGMNA INLPLSPIPF ELDPEDTMLE ENEVRTMVDP
60 70 80 90 100
NSRSDPKLQE LMKVLIDWIN DVLVGERIIV KDLAEDLYDG QVLQKLFEKL
110 120 130 140 150
ESEKLNVAEV TQSEIAQKQK LQTVLEKINE TLKLPPRSIK WNVDSVHAKS
160 170 180 190 200
LVAILHLLVA LSQYFRAPIR LPDHVSIQVV VVQKREGILQ SRQIQEEITG

NTEALSGRH
Length:209
Mass (Da):23,620
Last modified:April 5, 2011 - v1
Checksum:i43D522A39C9D0040
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9NVD7PARVA_HUMAN
Alpha-parvin
PARVA MXRA2
372Annotation score:
J3KNQ4J3KNQ4_HUMAN
Alpha-parvin
PARVA hCG_23646
412Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei209Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009806 Genomic DNA No translation available.
AC025300 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000528916; ENSP00000435860; ENSG00000197702
UCSCiuc057zfi.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009806 Genomic DNA No translation available.
AC025300 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliE9PS97
SMRiE9PS97
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiE9PS97
PeptideAtlasiE9PS97
PRIDEiE9PS97

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000528916; ENSP00000435860; ENSG00000197702
UCSCiuc057zfi.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000197702.11
HGNCiHGNC:14652 PARVA
OpenTargetsiENSG00000197702
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3631 Eukaryota
ENOG410XQWH LUCA
GeneTreeiENSGT00390000009673

Miscellaneous databases

ChiTaRSiPARVA human

Gene expression databases

BgeeiENSG00000197702 Expressed in 225 organ(s), highest expression level in lower esophagus
ExpressionAtlasiE9PS97 baseline and differential

Family and domain databases

Gene3Di1.10.418.10, 1 hit
InterProiView protein in InterPro
IPR001715 CH-domain
IPR036872 CH_dom_sf
IPR028433 Parvin
PANTHERiPTHR12114 PTHR12114, 1 hit
PfamiView protein in Pfam
PF00307 CH, 1 hit
SUPFAMiSSF47576 SSF47576, 1 hit
PROSITEiView protein in PROSITE
PS50021 CH, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE9PS97_HUMAN
AccessioniPrimary (citable) accession number: E9PS97
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: September 12, 2018
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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