UniProtKB - E9PS96 (E9PS96_HUMAN)

BLAST

>tr|E9PS96|E9PS96_HUMAN Regulator of G-protein-signaling 5 (Fragment) OS=Homo sapiens OX=9606 GN=RGS5 PE=1 SV=1
MCKGLAALPHSCLERTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIAC
EDYKKIKSPAK

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History
Entry version 41 (12 Sep 2018)
Sequence version 1 (05 Apr 2011)
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Protein

Submitted name:

Regulator of G-protein-signaling 5

Gene

RGS5

Organism

Homo sapiens (Human)

Status

Unreviewed-Annotation score: -Experimental evidence at protein levelⁱ

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Regulator of G-protein-signaling 5Imported
Gene namesⁱ	Name:RGS5Imported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 1

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000143248.12
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:10001 RGS5

Pathology & Biotechⁱ

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000143248

OpenTargetsⁱ

ENSG00000143248

PTM / Processingⁱ

Proteomic databases

PRIDEⁱ	E9PS96

PRIDEⁱ

E9PS96

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000143248 Expressed in 252 organ(s), highest expression level in blood vessel layer
ExpressionAtlasⁱ	E9PS96 baseline and differential

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	E9PS96
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	27 – 71	RGSInterPro annotationAdd BLAST		45

Phylogenomic databases

Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000118903

GeneTreeⁱ

ENSGT00760000118903

Family and domain databases

Gene3Dⁱ	1.10.196.10, 1 hit
InterProⁱ	View protein in InterPro IPR016137 RGS IPR034955 RGS5 IPR036305 RGS_sf IPR024066 RGS_subdom1/3
PANTHERⁱ	PTHR10845:SF42 PTHR10845:SF42, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00615 RGS, 1 hit
PRINTSⁱ	PR01301 RGSPROTEIN
SUPFAMⁱ	SSF48097 SSF48097, 1 hit
PROSITEⁱ	View protein in PROSITE PS50132 RGS, 1 hit

Sequence (1+)ⁱ

Sequence statusⁱ: Fragment.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show all Align All

E9PS96-1 [UniParc]FASTA Add to basket

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        10         20         30         40         50
MCKGLAALPH SCLERTSLDE ALQWRDSLDK LLQNNYGLAS FKSFLKSEFS 
        60         70 
EENLEFWIAC EDYKKIKSPA K

Length:71

Mass (Da):8,187

Last modified:April 5, 2011 - v1

Checksum:ⁱB72567B67209CC7E

Computationally mapped potential isoform sequencesⁱ

There are 2 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

O15539	RGS5_HUMAN	Regulator of G-protein signaling 5 Regulator of G-protein signaling 5, RGS5	RGS5	181	Annotation score:
B1APM2	B1APM2_HUMAN	Regulator of G-protein signalling 5... Regulator of G-protein signalling 5, isoform CRA_a (Regulator of G-protein-signaling 5)	RGS5 hCG_15193	201	Annotation score:

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Non-terminal residueⁱ	71	Imported		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL451063 Genomic DNA No translation available. AL499616 Genomic DNA No translation available. AL583850 Genomic DNA No translation available. AL592435 Genomic DNA No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AL451063 Genomic DNA No translation available.
AL499616 Genomic DNA No translation available.
AL583850 Genomic DNA No translation available.
AL592435 Genomic DNA No translation available.

Genome annotation databases

Ensemblⁱ	ENST00000531476; ENSP00000435861; ENSG00000143248
UCSC genome browser More...UCSCⁱ	uc057mvy.1 human

Protein	Similar proteins		Species	Score	Length	Source
E9PS96	RGS5 isoform 10 (Fragment)		PONAB		71	UniRef90_E9PS96
RGS5 isoform 10 (Fragment)		PANTR		71

Protein	Similar proteins		Species	Score	Length	Source
E9PS96	RGS5 isoform 10 (Fragment)		PONAB		71	UniRef50_E9PS96
RGS5 isoform 10 (Fragment)		PANTR		71

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL451063 Genomic DNA No translation available. AL499616 Genomic DNA No translation available. AL583850 Genomic DNA No translation available. AL592435 Genomic DNA No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AL451063 Genomic DNA No translation available.
AL499616 Genomic DNA No translation available.
AL583850 Genomic DNA No translation available.
AL592435 Genomic DNA No translation available.

3D structure databases

ProteinModelPortalⁱ	E9PS96
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Proteomic databases

PRIDEⁱ	E9PS96

PRIDEⁱ

E9PS96

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000531476; ENSP00000435861; ENSG00000143248
UCSCⁱ	uc057mvy.1 human

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000143248.12
HGNCⁱ	HGNC:10001 RGS5
OpenTargetsⁱ	ENSG00000143248
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

GeneTreeⁱ	ENSGT00760000118903

GeneTreeⁱ

ENSGT00760000118903

Miscellaneous databases

ChiTaRSⁱ	RGS5 human

ChiTaRSⁱ

RGS5 human

Gene expression databases

Bgeeⁱ	ENSG00000143248 Expressed in 252 organ(s), highest expression level in blood vessel layer
ExpressionAtlasⁱ	E9PS96 baseline and differential

Family and domain databases

Gene3Dⁱ	1.10.196.10, 1 hit
InterProⁱ	View protein in InterPro IPR016137 RGS IPR034955 RGS5 IPR036305 RGS_sf IPR024066 RGS_subdom1/3
PANTHERⁱ	PTHR10845:SF42 PTHR10845:SF42, 1 hit
Pfamⁱ	View protein in Pfam PF00615 RGS, 1 hit
PRINTSⁱ	PR01301 RGSPROTEIN
SUPFAMⁱ	SSF48097 SSF48097, 1 hit
PROSITEⁱ	View protein in PROSITE PS50132 RGS, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	E9PS96_HUMAN
Accessionⁱ	E9PS96Primary (citable) accession number: E9PS96
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	April 5, 2011
	Last sequence update:	April 5, 2011
	Last modified:	September 12, 2018
	This is version 41 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

UniProtKB - E9PS96 (E9PS96_HUMAN)

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Regulator of G-protein-signaling 5

RGS5

Select a section on the left to see content.

Names & Taxonomyⁱ

Organism-specific databases

Pathology & Biotechⁱ

Organism-specific databases

PTM / Processingⁱ

Proteomic databases

Expressionⁱ

Gene expression databases

Structureⁱ

3D structure databases

Family & Domainsⁱ

Domains and Repeats

Phylogenomic databases

Family and domain databases

Sequence (1+)ⁱ

Computationally mapped potential isoform sequencesⁱ

Experimental Info

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

UniProt is an ELIXIR core data resource

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Supporting data

UniProtKB - E9PS96 (E9PS96_HUMAN)

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Regulator of G-protein-signaling 5

RGS5

Select a section on the left to see content.

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

UniProt is an ELIXIR core data resource

Your basket is currently empty. ⁱ

Names & Taxonomyⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Structureⁱ

Family & Domainsⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ