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Protein
Submitted name:

Receptor-type tyrosine-protein phosphatase kappa

Gene

PTPRK

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Receptor-type tyrosine-protein phosphatase kappaImported
Gene namesi
Name:PTPRKImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 6

Organism-specific databases

EuPathDBiHostDB:ENSG00000152894.14
HGNCiHGNC:9674 PTPRK

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei164 – 186HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000152894

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 27Sequence analysisAdd BLAST27
ChainiPRO_501457101028 – 248Sequence analysisAdd BLAST221

Proteomic databases

MaxQBiE9PRW2
PRIDEiE9PRW2

Expressioni

Gene expression databases

BgeeiENSG00000152894

Structurei

3D structure databases

SMRiE9PRW2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini34 – 168MAMInterPro annotationAdd BLAST135

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG4228 Eukaryota
COG5599 LUCA
GeneTreeiENSGT00760000118900

Family and domain databases

CDDicd06263 MAM, 1 hit
InterProiView protein in InterPro
IPR013320 ConA-like_dom_sf
IPR000998 MAM_dom
PfamiView protein in Pfam
PF00629 MAM, 1 hit
PRINTSiPR00020 MAMDOMAIN
SMARTiView protein in SMART
SM00137 MAM, 1 hit
SUPFAMiSSF49899 SSF49899, 1 hit
PROSITEiView protein in PROSITE
PS00740 MAM_1, 1 hit
PS50060 MAM_2, 1 hit

Sequencei

Sequence statusi: Complete.

E9PRW2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDTTAAAALP AFVALLLLSP WPLLGSAQGQ FSAGGCTFDD GPGACDYHQD
60 70 80 90 100
LYDDFEWVHV SAQEPHYLPP EMPQGSYMIV DSSDHDPGEK ARLQLPTMKE
110 120 130 140 150
NDTHCIDFSY LLYSQKGLNP GTLNILVRVN KGPLANPIWN VTGFTGRDWL
160 170 180 190 200
RAELAVSTFW PNEYQVIICT FLVYVLMSSV LTICVIHRCK YASHGNERLP
210 220 230 240
SCLPHPHYWG SVIHRYTYAS HGNERLPLFL PHPVDEEVFG DIGTKPSN
Length:248
Mass (Da):27,691
Last modified:April 5, 2011 - v1
Checksum:iD4C62AEEE98ACDD6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC212491 Genomic DNA No translation available.
AL035465 Genomic DNA No translation available.
AL035470 Genomic DNA No translation available.
AL035594 Genomic DNA No translation available.
AL357621 Genomic DNA No translation available.
AL451073 Genomic DNA No translation available.
AL590006 Genomic DNA No translation available.
KF458278 Genomic DNA No translation available.
KF458282 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000525459; ENSP00000434116; ENSG00000152894
ENST00000628472; ENSP00000486448; ENSG00000273993
UCSCiuc063rgo.1 human

Similar proteinsi

Entry informationi

Entry nameiE9PRW2_HUMAN
AccessioniPrimary (citable) accession number: E9PRW2
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: July 18, 2018
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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