UniProtKB - E9PQX1 (TM262_HUMAN)
Protein
Transmembrane protein 262
Gene
TMEM262
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Recommended name: Transmembrane protein 262 |
Gene namesi | Name:TMEM262 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000187066.8 |
HGNCi | HGNC:49389, TMEM262 |
neXtProti | NX_E9PQX1 |
Subcellular locationi
Other locations
- Membrane Curated; Multi-pass membrane protein Curated
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 14 – 34 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 55 – 75 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 89 – 109 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
MembranePathology & Biotechi
Organism-specific databases
OpenTargetsi | ENSG00000187066 |
Miscellaneous databases
Pharosi | E9PQX1, Tdark |
Polymorphism and mutation databases
BioMutai | TMEM262 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000424961 | 1 – 116 | Transmembrane protein 262Add BLAST | 116 |
Proteomic databases
MassIVEi | E9PQX1 |
PaxDbi | E9PQX1 |
PeptideAtlasi | E9PQX1 |
PRIDEi | E9PQX1 |
ProteomicsDBi | 23144 |
Expressioni
Gene expression databases
Bgeei | ENSG00000187066, Expressed in metanephric glomerulus and 144 other tissues |
ExpressionAtlasi | E9PQX1, baseline and differential |
Organism-specific databases
HPAi | ENSG00000187066, Tissue enriched (testis) |
Interactioni
Binary interactionsi
Hide detailsE9PQX1
Protein-protein interaction databases
BioGRIDi | 934641, 13 interactors |
IntActi | E9PQX1, 12 interactors |
Miscellaneous databases
RNActi | E9PQX1, protein |
Family & Domainsi
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | ENOG502S7IB, Eukaryota |
GeneTreei | ENSGT00530000064783 |
HOGENOMi | CLU_160801_0_0_1 |
InParanoidi | E9PQX1 |
OMAi | DKFLRCF |
OrthoDBi | 1596404at2759 |
PhylomeDBi | E9PQX1 |
Family and domain databases
InterProi | View protein in InterPro IPR040431, TM262 |
PANTHERi | PTHR37998, PTHR37998, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All
E9PQX1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MWLQDRIATF FFPKGMMLTT AALMLFFLHL GIFIRDVHNF CITYHYDHMS
60 70 80 90 100
FHYTVVLMFS QVISICWAAM GSLYAEMTEN KYVCFSALTI LMLNGAMFFN
110
RLSLEFLAIE YREEHH
Computationally mapped potential isoform sequencesi
There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketH0YEQ3 | H0YEQ3_HUMAN | Transmembrane protein 262 | TMEM262 | 112 | Annotation score: | ||
E9PME8 | E9PME8_HUMAN | Transmembrane protein 262 | TMEM262 | 106 | Annotation score: | ||
A0A096LNV8 | A0A096LNV8_HUMAN | Transmembrane protein 262 | TMEM262 | 110 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 2 | W → R in HY032040 (Ref. 2) Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AP003068 Genomic DNA No translation available. HY032040 mRNA No translation available. |
CCDSi | CCDS60845.1 |
RefSeqi | NP_001269377.1, NM_001282448.1 |
Genome annotation databases
Ensembli | ENST00000530719; ENSP00000432459; ENSG00000187066 |
GeneIDi | 100130348 |
KEGGi | hsa:100130348 |
UCSCi | uc031xrs.2, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AP003068 Genomic DNA No translation available. HY032040 mRNA No translation available. |
CCDSi | CCDS60845.1 |
RefSeqi | NP_001269377.1, NM_001282448.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 934641, 13 interactors |
IntActi | E9PQX1, 12 interactors |
Polymorphism and mutation databases
BioMutai | TMEM262 |
Proteomic databases
MassIVEi | E9PQX1 |
PaxDbi | E9PQX1 |
PeptideAtlasi | E9PQX1 |
PRIDEi | E9PQX1 |
ProteomicsDBi | 23144 |
Genome annotation databases
Ensembli | ENST00000530719; ENSP00000432459; ENSG00000187066 |
GeneIDi | 100130348 |
KEGGi | hsa:100130348 |
UCSCi | uc031xrs.2, human |
Organism-specific databases
CTDi | 100130348 |
EuPathDBi | HostDB:ENSG00000187066.8 |
GeneCardsi | TMEM262 |
HGNCi | HGNC:49389, TMEM262 |
HPAi | ENSG00000187066, Tissue enriched (testis) |
neXtProti | NX_E9PQX1 |
OpenTargetsi | ENSG00000187066 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | ENOG502S7IB, Eukaryota |
GeneTreei | ENSGT00530000064783 |
HOGENOMi | CLU_160801_0_0_1 |
InParanoidi | E9PQX1 |
OMAi | DKFLRCF |
OrthoDBi | 1596404at2759 |
PhylomeDBi | E9PQX1 |
Enzyme and pathway databases
PathwayCommonsi | E9PQX1 |
Miscellaneous databases
BioGRID-ORCSi | 100130348, 4 hits in 791 CRISPR screens |
ChiTaRSi | TMEM262, human |
GenomeRNAii | 100130348 |
Pharosi | E9PQX1, Tdark |
PROi | PR:E9PQX1 |
RNActi | E9PQX1, protein |
Gene expression databases
Bgeei | ENSG00000187066, Expressed in metanephric glomerulus and 144 other tissues |
ExpressionAtlasi | E9PQX1, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR040431, TM262 |
PANTHERi | PTHR37998, PTHR37998, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | TM262_HUMAN | |
Accessioni | E9PQX1Primary (citable) accession number: E9PQX1 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 22, 2014 |
Last sequence update: | April 5, 2011 | |
Last modified: | December 2, 2020 | |
This is version 52 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Human chromosome 11
Human chromosome 11: entries, gene names and cross-references to MIM