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Protein
Submitted name:

Gasdermin-D

Gene

GSDMD

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Gasdermin-DImported
Gene namesi
Name:GSDMDImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 8

Organism-specific databases

EuPathDBiHostDB:ENSG00000104518.10
HGNCiHGNC:25697 GSDMD

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000104518

PTM / Processingi

Proteomic databases

MaxQBiE9PQR9
PRIDEiE9PQR9

Expressioni

Gene expression databases

BgeeiENSG00000104518 Expressed in 171 organ(s), highest expression level in spleen
ExpressionAtlasiE9PQR9 baseline and differential

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410IKA4 Eukaryota
ENOG4111D9N LUCA
GeneTreeiENSGT00530000063218

Family and domain databases

InterProiView protein in InterPro
IPR007677 Gasdermin
PANTHERiPTHR16399 PTHR16399, 1 hit
PfamiView protein in Pfam
PF04598 Gasdermin, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All

E9PQR9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGSAFERVVR RVVQELDHGG EFIPVTSLQS STGFQPYCLV VRKPSSSWFW
60 70 80 90 100
KPRYKCVNLS IKDILEPDAA EPDVQRGRSF HFYDAMDGQI QGSVELAAPG
110 120 130 140 150
QAKIAGGAAV SDSSSTSMNV YSLSVDPNTW QTLLHERHLR QPEHKVLQQL
160
RSRGDNVYVV TEVL
Length:164
Mass (Da):18,320
Last modified:April 5, 2011 - v1
Checksum:iE158F47315732D57
GO

Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P57764GSDMD_HUMAN
Gasdermin-D
GSDMD DFNA5L, GSDMDC1, FKSG10
484Annotation score:
G3V1A6G3V1A6_HUMAN
Gasdermin domain containing 1, isof...
GSDMD GSDMDC1, hCG_32063
532Annotation score:
E9PIB2E9PIB2_HUMAN
Gasdermin-D
GSDMD
277Annotation score:
E9PQ48E9PQ48_HUMAN
Gasdermin-D
GSDMD
114Annotation score:
E9PRF1E9PRF1_HUMAN
Gasdermin-D
GSDMD
48Annotation score:
E9PNZ0E9PNZ0_HUMAN
Gasdermin-D
GSDMD
153Annotation score:
H0YDB0H0YDB0_HUMAN
Gasdermin-D
GSDMD
231Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei164Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC067930 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000533348; ENSP00000434386; ENSG00000104518
ENST00000633391; ENSP00000487934; ENSG00000278718
UCSCiuc064qza.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC067930 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiE9PQR9
PRIDEiE9PQR9

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000533348; ENSP00000434386; ENSG00000104518
ENST00000633391; ENSP00000487934; ENSG00000278718
UCSCiuc064qza.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000104518.10
HGNCiHGNC:25697 GSDMD
OpenTargetsiENSG00000104518
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IKA4 Eukaryota
ENOG4111D9N LUCA
GeneTreeiENSGT00530000063218

Miscellaneous databases

ChiTaRSiGSDMD human

Gene expression databases

BgeeiENSG00000104518 Expressed in 171 organ(s), highest expression level in spleen
ExpressionAtlasiE9PQR9 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR007677 Gasdermin
PANTHERiPTHR16399 PTHR16399, 1 hit
PfamiView protein in Pfam
PF04598 Gasdermin, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE9PQR9_HUMAN
AccessioniPrimary (citable) accession number: E9PQR9
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: October 10, 2018
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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