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Protein
Submitted name:

Glycosylphosphatidylinositol anchor attachment 1 protein

Gene

GPAA1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Glycosylphosphatidylinositol anchor attachment 1 proteinImported
Gene namesi
Name:GPAA1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 8

Organism-specific databases

EuPathDBiHostDB:ENSG00000197858.10
HGNCiHGNC:4446 GPAA1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei20 – 41HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000197858

PTM / Processingi

Proteomic databases

PeptideAtlasiE9PQ31
PRIDEiE9PQ31

Expressioni

Gene expression databases

BgeeiENSG00000197858 Expressed in 226 organ(s), highest expression level in heart left ventricle
ExpressionAtlasiE9PQ31 baseline and differential

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3566 Eukaryota
ENOG410XT16 LUCA
GeneTreeiENSGT00390000013685

Family and domain databases

InterProiView protein in InterPro
IPR007246 Gaa1
PANTHERiPTHR13304 PTHR13304, 2 hits
PfamiView protein in Pfam
PF04114 Gaa1, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

E9PQ31-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGLLSDPVRR RALARLVLRL NAPLCVLSYV AGIAWFLALV FPPLTQRTYM
60 70 80 90 100
SENAMGSTMV EEQFAGGDRA RAFARDFAAH RKKSGQAVGL LLALAAHFRG
110 120 130 140 150
QIYWAKDIVF LVTEHDLLGT EAWLEAYHDV NVTGMQSSPL QGRAGAIQAA
160 170 180 190 200
VALELSSDVV TSLDVAVEGL NGQLPNLDLL NLFQTFCQKG GLLCTLQGKL
210 220 230 240 250
QPEDWTSLDG PLQGLQTLLL MVLRQASGRP HGSHGLFLRY RVEALTLRGI
260 270
NSFRQYKYDL VAVGKALEGM FRK
Length:273
Mass (Da):29,984
Last modified:October 29, 2014 - v2
Checksum:iA6B139C401744B32
GO

Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
O43292GPAA1_HUMAN
Glycosylphosphatidylinositol anchor...
GPAA1 GAA1
621Annotation score:
E9PLV6E9PLV6_HUMAN
Glycosylphosphatidylinositol anchor...
GPAA1
234Annotation score:
E9PPZ9E9PPZ9_HUMAN
Glycosylphosphatidylinositol anchor...
GPAA1
260Annotation score:
E9PM11E9PM11_HUMAN
Glycosylphosphatidylinositol anchor...
GPAA1
158Annotation score:
E9PLG8E9PLG8_HUMAN
Glycosylphosphatidylinositol anchor...
GPAA1
81Annotation score:
E9PM94E9PM94_HUMAN
Glycosylphosphatidylinositol anchor...
GPAA1
98Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei273Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC109322 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000525087; ENSP00000434485; ENSG00000197858
UCSCiuc064rhs.1 human

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC109322 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiE9PQ31
PRIDEiE9PQ31

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000525087; ENSP00000434485; ENSG00000197858
UCSCiuc064rhs.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000197858.10
HGNCiHGNC:4446 GPAA1
OpenTargetsiENSG00000197858
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3566 Eukaryota
ENOG410XT16 LUCA
GeneTreeiENSGT00390000013685

Gene expression databases

BgeeiENSG00000197858 Expressed in 226 organ(s), highest expression level in heart left ventricle
ExpressionAtlasiE9PQ31 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR007246 Gaa1
PANTHERiPTHR13304 PTHR13304, 2 hits
PfamiView protein in Pfam
PF04114 Gaa1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE9PQ31_HUMAN
AccessioniPrimary (citable) accession number: E9PQ31
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: October 29, 2014
Last modified: September 12, 2018
This is version 41 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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