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Protein
Submitted name:

Cell adhesion molecule-related/down-regulated by oncogenes

Gene

CDON

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Cell adhesion molecule-related/down-regulated by oncogenesImported
Gene namesi
Name:CDONImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000064309.14
HGNCiHGNC:17104 CDON

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000064309

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Sequence analysisAdd BLAST25
ChainiPRO_500841394826 – 142Sequence analysisAdd BLAST117

Proteomic databases

PeptideAtlasiE9PPQ7

Expressioni

Gene expression databases

BgeeiENSG00000064309 Expressed in 161 organ(s), highest expression level in layer of synovial tissue
ExpressionAtlasiE9PPQ7 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliE9PPQ7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini29 – 114Ig-likeInterPro annotationAdd BLAST86

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IHIH Eukaryota
ENOG410XSVT LUCA
GeneTreeiENSGT00930000150975

Family and domain databases

Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR032983 CDO
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003599 Ig_sub
IPR003598 Ig_sub2
PANTHERiPTHR44170:SF1 PTHR44170:SF1, 1 hit
SMARTiView protein in SMART
SM00409 IG, 1 hit
SM00408 IGc2, 1 hit
SUPFAMiSSF48726 SSF48726, 1 hit
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

E9PPQ7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MHPDLGPLCT LLYVTLTILC SSVSSDLAPY FTSEPLSAVQ KLGGPVVLHC
60 70 80 90 100
SAQPVTTRIS WLHNGKTLDG NLEHVKIHQG TLTILSLNSS LLGYYQCLAN
110 120 130 140
NSIGAIVSGP ATVSVAVLGD FGSSTKHVIT AEEKSAGFIG CR
Length:142
Mass (Da):14,894
Last modified:October 5, 2016 - v8
Checksum:i7CBD77D06E49891D
GO

Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q4KMG0CDON_HUMAN
Cell adhesion molecule-related/down...
CDON CDO
1,287Annotation score:
E9PNF2E9PNF2_HUMAN
Cell adhesion molecule-related/down...
CDON
111Annotation score:
E9PRD8E9PRD8_HUMAN
Cell adhesion molecule-related/down...
CDON
165Annotation score:
E9PN78E9PN78_HUMAN
Cell adhesion molecule-related/down...
CDON
641Annotation score:
H0YEX4H0YEX4_HUMAN
Cell adhesion molecule-related/down...
CDON
650Annotation score:
H0YCZ4H0YCZ4_HUMAN
Cell adhesion molecule-related/down...
CDON
243Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei142Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP000821 Genomic DNA No translation available.
AP000842 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000527967; ENSP00000436940; ENSG00000064309
UCSCiuc058ixe.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP000821 Genomic DNA No translation available.
AP000842 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliE9PPQ7
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiE9PPQ7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000527967; ENSP00000436940; ENSG00000064309
UCSCiuc058ixe.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000064309.14
HGNCiHGNC:17104 CDON
OpenTargetsiENSG00000064309
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IHIH Eukaryota
ENOG410XSVT LUCA
GeneTreeiENSGT00930000150975

Miscellaneous databases

ChiTaRSiCDON human

Gene expression databases

BgeeiENSG00000064309 Expressed in 161 organ(s), highest expression level in layer of synovial tissue
ExpressionAtlasiE9PPQ7 baseline and differential

Family and domain databases

Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR032983 CDO
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003599 Ig_sub
IPR003598 Ig_sub2
PANTHERiPTHR44170:SF1 PTHR44170:SF1, 1 hit
SMARTiView protein in SMART
SM00409 IG, 1 hit
SM00408 IGc2, 1 hit
SUPFAMiSSF48726 SSF48726, 1 hit
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE9PPQ7_HUMAN
AccessioniPrimary (citable) accession number: E9PPQ7
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: October 5, 2016
Last modified: November 7, 2018
This is version 57 of the entry and version 8 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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