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Protein
Submitted name:

Radixin

Gene

RDX

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
RadixinImported
Gene namesi
Name:RDXImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000137710.14
HGNCiHGNC:9944 RDX

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000137710

PTM / Processingi

Proteomic databases

EPDiE9PNV3
MaxQBiE9PNV3
PeptideAtlasiE9PNV3
PRIDEiE9PNV3

Expressioni

Gene expression databases

BgeeiENSG00000137710 Expressed in 239 organ(s), highest expression level in metanephros
ExpressionAtlasiE9PNV3 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliE9PNV3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 148FERMInterPro annotationAdd BLAST148

Phylogenomic databases

eggNOGiKOG3529 Eukaryota
ENOG410XQFP LUCA
GeneTreeiENSGT00920000148976

Family and domain databases

CDDicd14473 FERM_B-lobe, 1 hit
InterProiView protein in InterPro
IPR019749 Band_41_domain
IPR000798 Ez/rad/moesin-like
IPR035963 FERM_2
IPR019748 FERM_central
IPR019747 FERM_CS
IPR000299 FERM_domain
IPR018979 FERM_N
IPR029071 Ubiquitin-like_domsf
PfamiView protein in Pfam
PF00373 FERM_M, 1 hit
PF09379 FERM_N, 1 hit
PRINTSiPR00935 BAND41
PR00661 ERMFAMILY
SMARTiView protein in SMART
SM00295 B41, 1 hit
SUPFAMiSSF47031 SSF47031, 1 hit
SSF54236 SSF54236, 1 hit
PROSITEiView protein in PROSITE
PS00660 FERM_1, 1 hit
PS50057 FERM_3, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 10 potential isoforms that are computationally mapped.Show allAlign All

E9PNV3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDAELEFAIQ PNTTGKQLFD QVVKTVGLRE VWFFGLQYVD SKGYSTWLKL
60 70 80 90 100
NKKVTQQDVK KENPLQFKFR AKFFPEDVSE ELIQEITQRL FFLQVKEAIL
110 120 130 140
NDEIYCPPET AVLLASYAVQ AKYGDYNKEI HKPGYLANDR LLPQRVLE
Length:148
Mass (Da):17,283
Last modified:April 5, 2011 - v1
Checksum:iE234C49FBA18DCBE
GO

Computationally mapped potential isoform sequencesi

There are 10 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P35241RADI_HUMAN
Radixin
RDX
583Annotation score:
A0A2R8Y5S7A0A2R8Y5S7_HUMAN
Radixin
RDX
590Annotation score:
A0A2R8Y7M3A0A2R8Y7M3_HUMAN
Radixin
RDX
534Annotation score:
E9PQ82E9PQ82_HUMAN
Radixin
RDX
116Annotation score:
A0A2R8Y4H6A0A2R8Y4H6_HUMAN
Radixin
RDX
152Annotation score:
A0A2R8Y5P0A0A2R8Y5P0_HUMAN
Radixin
RDX
115Annotation score:
E9PKN5E9PKN5_HUMAN
Radixin
RDX
51Annotation score:
E9PNP4E9PNP4_HUMAN
Radixin
RDX
52Annotation score:
E9PRS5E9PRS5_HUMAN
Radixin
RDX
44Annotation score:
E9PN07E9PN07_HUMAN
Radixin
RDX
50Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei148Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001889 Genomic DNA No translation available.
AP001981 Genomic DNA No translation available.
KF455503 Genomic DNA No translation available.
KF510350 Genomic DNA No translation available.
KF511111 Genomic DNA No translation available.
KF511113 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000532118; ENSP00000437140; ENSG00000137710
UCSCiuc058hdk.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001889 Genomic DNA No translation available.
AP001981 Genomic DNA No translation available.
KF455503 Genomic DNA No translation available.
KF510350 Genomic DNA No translation available.
KF511111 Genomic DNA No translation available.
KF511113 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliE9PNV3
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

EPDiE9PNV3
MaxQBiE9PNV3
PeptideAtlasiE9PNV3
PRIDEiE9PNV3

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000532118; ENSP00000437140; ENSG00000137710
UCSCiuc058hdk.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000137710.14
HGNCiHGNC:9944 RDX
OpenTargetsiENSG00000137710
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3529 Eukaryota
ENOG410XQFP LUCA
GeneTreeiENSGT00920000148976

Miscellaneous databases

ChiTaRSiRDX human

Gene expression databases

BgeeiENSG00000137710 Expressed in 239 organ(s), highest expression level in metanephros
ExpressionAtlasiE9PNV3 baseline and differential

Family and domain databases

CDDicd14473 FERM_B-lobe, 1 hit
InterProiView protein in InterPro
IPR019749 Band_41_domain
IPR000798 Ez/rad/moesin-like
IPR035963 FERM_2
IPR019748 FERM_central
IPR019747 FERM_CS
IPR000299 FERM_domain
IPR018979 FERM_N
IPR029071 Ubiquitin-like_domsf
PfamiView protein in Pfam
PF00373 FERM_M, 1 hit
PF09379 FERM_N, 1 hit
PRINTSiPR00935 BAND41
PR00661 ERMFAMILY
SMARTiView protein in SMART
SM00295 B41, 1 hit
SUPFAMiSSF47031 SSF47031, 1 hit
SSF54236 SSF54236, 1 hit
PROSITEiView protein in PROSITE
PS00660 FERM_1, 1 hit
PS50057 FERM_3, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE9PNV3_HUMAN
AccessioniPrimary (citable) accession number: E9PNV3
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: September 12, 2018
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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