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Protein
Submitted name:

Growth arrest-specific protein 2

Gene

GAS2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Growth arrest-specific protein 2Imported
Gene namesi
Name:GAS2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000148935.10
HGNCiHGNC:4167 GAS2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000148935

PTM / Processingi

Proteomic databases

MaxQBiE9PM28
PeptideAtlasiE9PM28

Expressioni

Gene expression databases

BgeeiENSG00000148935 Expressed in 174 organ(s), highest expression level in liver
ExpressionAtlasiE9PM28 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliE9PM28
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini34 – 155Calponin-homology (CH)InterPro annotationAdd BLAST122

Phylogenomic databases

eggNOGiENOG410IQBT Eukaryota
ENOG4111BF1 LUCA
GeneTreeiENSGT00390000002205

Family and domain databases

CDDicd00014 CH, 1 hit
Gene3Di1.10.418.10, 1 hit
InterProiView protein in InterPro
IPR001715 CH-domain
IPR036872 CH_dom_sf
IPR029932 GAS2L3
PANTHERiPTHR44885 PTHR44885, 1 hit
PfamiView protein in Pfam
PF00307 CH, 1 hit
SMARTiView protein in SMART
SM00033 CH, 1 hit
SUPFAMiSSF47576 SSF47576, 1 hit
PROSITEiView protein in PROSITE
PS50021 CH, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

E9PM28-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MCTALSPKVR SGPGLSDMHQ YSQWLASRHE ANLLPMKEDL ALWLTNLLGK
60 70 80 90 100
EITAETFMEK LDNGALLCQL AETMQEKFKE SMDANKPTKN LPLKKIPCKT
110 120 130 140 150
SAPSGSFFAR DNTANFLSWC RDLGVDETCL FESEGLVLHK QPREVCLCLL

ELGRI
Length:155
Mass (Da):17,390
Last modified:April 5, 2011 - v1
Checksum:i3094A3BF601161F8
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
O43903GAS2_HUMAN
Growth arrest-specific protein 2
GAS2
313Annotation score:
E9PQ74E9PQ74_HUMAN
Growth arrest-specific protein 2
GAS2
181Annotation score:
E9PRR5E9PRR5_HUMAN
Growth arrest-specific protein 2
GAS2
205Annotation score:
E9PQ37E9PQ37_HUMAN
Growth arrest-specific protein 2
GAS2
136Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei155Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC006299 Genomic DNA No translation available.
AC103801 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000534801; ENSP00000433182; ENSG00000148935
UCSCiuc057zwa.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC006299 Genomic DNA No translation available.
AC103801 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliE9PM28
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiE9PM28
PeptideAtlasiE9PM28

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000534801; ENSP00000433182; ENSG00000148935
UCSCiuc057zwa.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000148935.10
HGNCiHGNC:4167 GAS2
OpenTargetsiENSG00000148935
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IQBT Eukaryota
ENOG4111BF1 LUCA
GeneTreeiENSGT00390000002205

Miscellaneous databases

ChiTaRSiGAS2 human

Gene expression databases

BgeeiENSG00000148935 Expressed in 174 organ(s), highest expression level in liver
ExpressionAtlasiE9PM28 baseline and differential

Family and domain databases

CDDicd00014 CH, 1 hit
Gene3Di1.10.418.10, 1 hit
InterProiView protein in InterPro
IPR001715 CH-domain
IPR036872 CH_dom_sf
IPR029932 GAS2L3
PANTHERiPTHR44885 PTHR44885, 1 hit
PfamiView protein in Pfam
PF00307 CH, 1 hit
SMARTiView protein in SMART
SM00033 CH, 1 hit
SUPFAMiSSF47576 SSF47576, 1 hit
PROSITEiView protein in PROSITE
PS50021 CH, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE9PM28_HUMAN
AccessioniPrimary (citable) accession number: E9PM28
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: September 12, 2018
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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