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Protein
Submitted name:

Transforming growth factor beta regulator 1

Gene

TBRG1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Transforming growth factor beta regulator 1Imported
Gene namesi
Name:TBRG1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000154144.12
HGNCiHGNC:29551 TBRG1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000154144

PTM / Processingi

Proteomic databases

PeptideAtlasiE9PK87

Expressioni

Gene expression databases

BgeeiENSG00000154144 Expressed in 196 organ(s), highest expression level in small intestine Peyer's patch
ExpressionAtlasiE9PK87 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini35 – 94FYR N-terminalInterPro annotationAdd BLAST60

Phylogenomic databases

eggNOGiENOG410ITPM Eukaryota
ENOG410XTBM LUCA
GeneTreeiENSGT00390000013374

Family and domain databases

InterProiView protein in InterPro
IPR003888 FYrich_N
PfamiView protein in Pfam
PF05964 FYRN, 1 hit
SMARTiView protein in SMART
SM00541 FYRN, 1 hit
PROSITEiView protein in PROSITE
PS51542 FYRN, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

E9PK87-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSLLDGLASS PRAPLQSSKA RMKKLPKKSQ NEKYRLKYLR LRKAAKATVF
60 70 80 90 100
IITDRPGFHD ESAIYPVGYC STRIYASMKC PDQKCLYTCQ IKDGGVQPQF
110
EIVPEDDPQN AI
Length:112
Mass (Da):12,655
Last modified:October 5, 2016 - v8
Checksum:i49C8E48F9A4425CE
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q3YBR2TBRG1_HUMAN
Transforming growth factor beta reg...
TBRG1 NIAM
411Annotation score:
E9PI10E9PI10_HUMAN
Transforming growth factor beta reg...
TBRG1
101Annotation score:
F8W6N5F8W6N5_HUMAN
Transforming growth factor beta reg...
TBRG1
160Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei112Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001524 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000531667; ENSP00000435448; ENSG00000154144
UCSCiuc058iqr.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001524 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiE9PK87

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000531667; ENSP00000435448; ENSG00000154144
UCSCiuc058iqr.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000154144.12
HGNCiHGNC:29551 TBRG1
OpenTargetsiENSG00000154144
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410ITPM Eukaryota
ENOG410XTBM LUCA
GeneTreeiENSGT00390000013374

Miscellaneous databases

ChiTaRSiTBRG1 human

Gene expression databases

BgeeiENSG00000154144 Expressed in 196 organ(s), highest expression level in small intestine Peyer's patch
ExpressionAtlasiE9PK87 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR003888 FYrich_N
PfamiView protein in Pfam
PF05964 FYRN, 1 hit
SMARTiView protein in SMART
SM00541 FYRN, 1 hit
PROSITEiView protein in PROSITE
PS51542 FYRN, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE9PK87_HUMAN
AccessioniPrimary (citable) accession number: E9PK87
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: October 5, 2016
Last modified: September 12, 2018
This is version 54 of the entry and version 8 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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