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Protein
Submitted name:

Aldehyde dehydrogenase family 3 member B2

Gene

ALDH3B2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei129PROSITE-ProRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductaseUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Aldehyde dehydrogenase family 3 member B2Imported
Gene namesi
Name:ALDH3B2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000132746.14
HGNCiHGNC:411 ALDH3B2

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000132746

PTM / Processingi

Proteomic databases

EPDiE9PJV0
PeptideAtlasiE9PJV0
PRIDEiE9PJV0

Expressioni

Gene expression databases

BgeeiENSG00000132746 Expressed in 101 organ(s), highest expression level in esophagus mucosa
ExpressionAtlasiE9PJV0 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliE9PJV0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini17 – 145AldedhInterPro annotationAdd BLAST129

Sequence similaritiesi

Belongs to the aldehyde dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG2456 Eukaryota
COG1012 LUCA
GeneTreeiENSGT00390000002825

Family and domain databases

Gene3Di3.40.309.10, 1 hit
3.40.605.10, 1 hit
InterProiView protein in InterPro
IPR016161 Ald_DH/histidinol_DH
IPR016163 Ald_DH_C
IPR029510 Ald_DH_CS_GLU
IPR016162 Ald_DH_N
IPR015590 Aldehyde_DH_dom
PfamiView protein in Pfam
PF00171 Aldedh, 1 hit
SUPFAMiSSF53720 SSF53720, 1 hit
PROSITEiView protein in PROSITE
PS00687 ALDEHYDE_DEHYDR_GLU, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

E9PJV0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKDEPRSTNL FMKLDSVFIW KEPFGLVLII APWNYPLNLT LVLLVGALAA
60 70 80 90 100
GSCVVLKPSE ISQGTEKVLA EVLPQYLDQS CFAVVLGGPQ ETGQLLEHKL
110 120 130 140
DYIFFTGSPR VGKIVMTAAT KHLTPVTLEL GGKNPCYVDD NCDPQTV
Length:147
Mass (Da):16,078
Last modified:October 5, 2016 - v8
Checksum:iB4121EB297399A3A
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P48448AL3B2_HUMAN
Aldehyde dehydrogenase family 3 mem...
ALDH3B2 ALDH8
385Annotation score:
H0YEC0H0YEC0_HUMAN
Aldehyde dehydrogenase family 3 mem...
ALDH3B2
128Annotation score:
E9PKY9E9PKY9_HUMAN
Aldehyde dehydrogenase family 3 mem...
ALDH3B2
94Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei147Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP003385 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000525827; ENSP00000433718; ENSG00000132746
UCSCiuc058ejy.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP003385 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliE9PJV0
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

EPDiE9PJV0
PeptideAtlasiE9PJV0
PRIDEiE9PJV0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000525827; ENSP00000433718; ENSG00000132746
UCSCiuc058ejy.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000132746.14
HGNCiHGNC:411 ALDH3B2
OpenTargetsiENSG00000132746
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2456 Eukaryota
COG1012 LUCA
GeneTreeiENSGT00390000002825

Miscellaneous databases

ChiTaRSiALDH3B2 human

Gene expression databases

BgeeiENSG00000132746 Expressed in 101 organ(s), highest expression level in esophagus mucosa
ExpressionAtlasiE9PJV0 baseline and differential

Family and domain databases

Gene3Di3.40.309.10, 1 hit
3.40.605.10, 1 hit
InterProiView protein in InterPro
IPR016161 Ald_DH/histidinol_DH
IPR016163 Ald_DH_C
IPR029510 Ald_DH_CS_GLU
IPR016162 Ald_DH_N
IPR015590 Aldehyde_DH_dom
PfamiView protein in Pfam
PF00171 Aldedh, 1 hit
SUPFAMiSSF53720 SSF53720, 1 hit
PROSITEiView protein in PROSITE
PS00687 ALDEHYDE_DEHYDR_GLU, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE9PJV0_HUMAN
AccessioniPrimary (citable) accession number: E9PJV0
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: October 5, 2016
Last modified: September 12, 2018
This is version 50 of the entry and version 8 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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