Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Nuclear pore complex-interacting protein family member A7

Gene

NPIPA7

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Nuclear pore complex-interacting protein family member A7
Gene namesi
Name:NPIPA7
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 16

Organism-specific databases

EuPathDBiHostDB:ENSG00000214967.5
HGNCiHGNC:41982 NPIPA7
neXtProtiNX_E9PJI5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000214940
ENSG00000214967

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004239251 – 369Nuclear pore complex-interacting protein family member A7Add BLAST369

Proteomic databases

PaxDbiE9PJI5
PRIDEiE9PJI5
ProteomicsDBi21151

PTM databases

iPTMnetiE9PJI5
PhosphoSitePlusiE9PJI5

Expressioni

Gene expression databases

BgeeiENSG00000214967 Expressed in 89 organ(s), highest expression level in pituitary gland
ExpressionAtlasiE9PJI5 baseline and differential
GenevisibleiE9PJI5 HS

Organism-specific databases

HPAiHPA053611

Interactioni

Binary interactionsi

Protein-protein interaction databases

IntActiE9PJI5, 2 interactors
STRINGi9606.ENSP00000435325

Structurei

3D structure databases

ProteinModelPortaliE9PJI5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi247 – 361Pro-richAdd BLAST115

Sequence similaritiesi

Belongs to the NPIP family.Curated

Phylogenomic databases

eggNOGiENOG410J0WZ Eukaryota
COG5069 LUCA
InParanoidiE9PJI5
OMAiCNSHSRE
OrthoDBiEOG091G0ETR
PhylomeDBiE9PJI5
TreeFamiTF333389

Family and domain databases

InterProiView protein in InterPro
IPR009443 NPIP
PANTHERiPTHR15438 PTHR15438, 2 hits
PfamiView protein in Pfam
PF06409 NPIP, 2 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

E9PJI5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFCCLGYEWL SGGCTTWHSA WVINTLADHR HRGTDFGGSP WLLIITVFLR
60 70 80 90 100
SYKFAISLCT SYLCVSFLKT IFPSQNGHDG STDVQQRARR SNRRRQEGIK
110 120 130 140 150
IVLEDIFTLW RQVETKVRAK IRKMKVTTKV NRHDKINGKR KTAKEHLRKL
160 170 180 190 200
SMKEREHREE ERQVSEAEEN GKLDMKEIHT YMEMFQRAQA LRRRAEDYYR
210 220 230 240 250
CKITPSARKP LCNRVRMAAV EHRHSSGLPY WPYLTAETLK NRMGHQPPPP
260 270 280 290 300
TQQHSIIDNS LSLKTPSECV LYPLPPSADD NLKTPPECLL TPLPPSALPS
310 320 330 340 350
ADDNLKTPAE CLLYPLPPSA DDNLKTPPEC LLTPLPPSAP PSADDNLKTP
360
PECVCSLPFH PQRMIISRN
Length:369
Mass (Da):42,230
Last modified:April 5, 2011 - v1
Checksum:i2046ED0883FA82B2
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H0Y2X3H0Y2X3_HUMAN
Nuclear pore complex-interacting pr...
NPIPA7
56Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC136619 Genomic DNA No translation available.
AC138969 Genomic DNA No translation available.
CCDSiCCDS61864.1
RefSeqiNP_001269436.1, NM_001282507.1
NP_001269440.1, NM_001282511.1
XP_016878323.1, XM_017022834.1
XP_016878324.1, XM_017022835.1
XP_016878331.1, XM_017022842.1
XP_016878332.1, XM_017022843.1
UniGeneiHs.634612
Hs.636569
Hs.720303

Genome annotation databases

EnsembliENST00000530217; ENSP00000431814; ENSG00000214967
GeneIDi101059938
101059953
KEGGihsa:101059938
hsa:101059953

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC136619 Genomic DNA No translation available.
AC138969 Genomic DNA No translation available.
CCDSiCCDS61864.1
RefSeqiNP_001269436.1, NM_001282507.1
NP_001269440.1, NM_001282511.1
XP_016878323.1, XM_017022834.1
XP_016878324.1, XM_017022835.1
XP_016878331.1, XM_017022842.1
XP_016878332.1, XM_017022843.1
UniGeneiHs.634612
Hs.636569
Hs.720303

3D structure databases

ProteinModelPortaliE9PJI5
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiE9PJI5, 2 interactors
STRINGi9606.ENSP00000435325

PTM databases

iPTMnetiE9PJI5
PhosphoSitePlusiE9PJI5

Proteomic databases

PaxDbiE9PJI5
PRIDEiE9PJI5
ProteomicsDBi21151

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000530217; ENSP00000431814; ENSG00000214967
GeneIDi101059938
101059953
KEGGihsa:101059938
hsa:101059953

Organism-specific databases

CTDi101059938
101059953
EuPathDBiHostDB:ENSG00000214967.5
GeneCardsiNPIPA7
HGNCiHGNC:41982 NPIPA7
HPAiHPA053611
neXtProtiNX_E9PJI5
OpenTargetsiENSG00000214940
ENSG00000214967
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410J0WZ Eukaryota
COG5069 LUCA
InParanoidiE9PJI5
OMAiCNSHSRE
OrthoDBiEOG091G0ETR
PhylomeDBiE9PJI5
TreeFamiTF333389

Miscellaneous databases

ChiTaRSiNPIPA7 human
PROiPR:E9PJI5

Gene expression databases

BgeeiENSG00000214967 Expressed in 89 organ(s), highest expression level in pituitary gland
ExpressionAtlasiE9PJI5 baseline and differential
GenevisibleiE9PJI5 HS

Family and domain databases

InterProiView protein in InterPro
IPR009443 NPIP
PANTHERiPTHR15438 PTHR15438, 2 hits
PfamiView protein in Pfam
PF06409 NPIP, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiNPIA7_HUMAN
AccessioniPrimary (citable) accession number: E9PJI5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 16, 2013
Last sequence update: April 5, 2011
Last modified: September 12, 2018
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 16
    Human chromosome 16: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again